r/Biohacking

I'm new at this, I'm 60 pounds overweight, a metabolic disaster, I've lost 20 lb in 2 months just doing tirz no exercise whatsoever apart from 8k steps daily. What do you think of this cycle? Planning on doing KB training at home.

I'm new at this, I'm 60 pounds overweight, a metabolic disaster, I've lost 20 lb in 2 months just doing tirz no exercise whatsoever apart from 8k steps daily. What do you think of this cycle? Planning on doing KB training at home.

u/burgerdiego — 3 hours ago

black speck in bac water

just ordered bac water from amazon canada. it’s a two pack with 2 10mL vials. one vial is completely fine and the other has a black speck. obviously not going to use that vial but do you think the other one is okay or should i just order from a different brand. also if anyone has canadian recommendations i would appreciate.

u/Fickle_Object8297 — 7 hours ago

Unbearable fatigue on Reta

I started Reta about 2 and a half weeks ago. I’m taking 1mg once a week, so I have only done two injections so far. The first 3 days after injecting I am almost non-functional. Like I can’t even get out of bed (which is not ideal because I have a very energetic toddler). I am really trying to prioritize getting enough protein, electrolytes, etc. but that doesn’t seem to help much. I’m interested to hear from people who have tried Reta.. do side effects typically diminish over time? Or will I likely continue to feel like this?

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u/Comfortable-Cloud342 — 10 hours ago

Possible endotoxin reaction?

Hello fellow biohackers!

So i have have been using HGH for some time and had some very unpleasant reactions the last 2 days when injecting 3iu.
On Sunday 30 minutes after i pinned i had severe shaking and shivers down my spine. The shivers were like every 3 or 4 seconds. Scary as fuck.
And the shaking was so intense that i was barely able to move. I felt an incredible coldness, as if i had a severe fever.
Sunday was also the first day of taking Quviviq to help me sleep. I thought i had some bad reaction to that medication - the HGH didnt even come to mind.
After stopping Quviviq immediately and proceeding to pin my usual 3iu like always, i had the almost exact same reaction yesterday again. Right after shooting my daily HGH.

Is it possible, that the reaction is caused by degradation of the peptide?
Endotoxin accumulation maybe?
I will be throwing that vial away obviously and start a new one. Same batch though, hopefully it was just this one.
The one i used Sunday and yesterday has been used for about 20 days at that point and was recon'd, desinfected and stored properly....

Anyone here with similar experiences when it comes to endotoxin reaction?
And what would you do in my case?

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u/edmspecialist — 6 hours ago
▲ 12 r/Biohacking+2 crossposts

Finnrick Becomes a Paid Subscription

This is the reason why they offer FREE testing to some basic peptides. WE are the product. WE are the data they needed for this subscription model.

u/Interesting-Roll9114 — 7 hours ago

Traveling w pep

Traveling to st Lucia soon - anyone have experience with traveling with peptides? Carry on? Ice packs? Are they going to ask questions?? Keep everything in a separate bag for easier security?

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u/Grand-Obligation971 — 10 hours ago

Gaining weight/remaining the same weight while on Reta

I have started Reta about a month ago, I just started a 3mg dose. I have the appetite suppression and the reduced food noise from it but I don’t seem to be losing any weight. I was 205 with a goal of reaching 170. I lost 7 lb since I started and I never lost more or gained more, but I looks like I lost weight and my clothes are fitting better than before where my belly would stick out I workout 3-5 times a week and I’m on a calorie deficit. I keep my protein intake at least 160g a day. Am I doing something wrong here?

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u/Agreeable_Pause8223 — 8 hours ago

Reta questions

Me and my wife are both on Reta we are on week 10 I 40yo M started at 290 now at 260 current dose is 2mg (also on 200mg topical testosterone twice daily MD prescribed) my wife 49yo F started at 340 and is now at 329 her current dose is 3mg (also on estrogen and progesterone MD prescribed). I am quite happy with the weight loss I have had. I stick to an 1800cal daily and we both go to the gym 1.5-2hr 3 times a week mostly strength training and some cardio each trip. My wife’s weight loss is stagnant for weeks then drop 5lb then stagnant again. She struggles to get 1000-1200cal daily with some days less than 1kcal. She struggles to even drink 8-10oz of protein shake made with milk in 1-2hr. Any suggestions or observations to help her with her weight loss.

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u/FlatwormBeneficial65 — 9 hours ago

[UPDATE] 6 weeks in: Retatrutide + CJC-1295 (no DAC)/Ipamorelin — body recomp progress + the appetite thing nobody prepared me for

Physician here, self-administering and tracking labs along the way. Sharing numbers + honest experience.

Protocol:
• Retatrutide: started 1.5mg/week (5/25), currently at 4mg/week
• CJC-1295 (no DAC) + Ipamorelin: 300mcg, Mon–Fri, before bed
• Resistance training 5x/week + 30min low-intensity fasted cardio post-workout
• Eating window: 12pm–6pm (~6h), protein-forward first meal at noon, whey shake at 6pm
• Daily intake: 800–1200 kcal, ~1–1.6g/kg protein

Numbers:
Day 1 (5/25) ————Now (6 wks)
Weight 97.7 kg ———————89.3 kg
Fat mass 30.6 kg (31.3%)——23.6 kg (26.4%)
Muscle mass 39.8 kg ———- 38.4 kg

−8.4 kg total, −7.0 kg fat, −1.4 kg muscle. Roughly a 5:1 fat-to-muscle loss ratio, which I’m
happy with given how aggressive the deficit has been.
What surprised me most: The food noise is just… gone. Not “under control” — gone. The
anxiety/craving loop around eating that used to sabotage every diet I tried isn’t there
anymore. I eat because I need to protect muscle mass, not because I’m hungry or anxious.
No fighting cravings for sugar or carbs, no “cheating,” none of the emotional labor dieting
usually costs me. Ironically I eat healthier now and enjoy it more, because the decision-
making is rational instead of driven by appetite.
CJC/Ipa’s contribution seems to be mostly sleep — noticeably deeper and longer, which I
think is helping the recomp side more than I expected.
Progress pics (day 1 vs now) attached.

Labs at week 4-5 (fasted panel):

•	Fasting glucose 4.2 mmol/L, HbA1c 4.9% — excellent, no signs of insulin resistance  
•	Fasting insulin 2.3 mIU/L (ref 2.6-24.9) — actually below range, reflecting how insulin-sensitive this combo makes you  
•	Lipids clean across the board: total cholesterol 3.93 mmol/L, LDL 2.36, HDL 1.11, triglycerides 0.81 mmol/L  
•	Thyroid panel euthyroid (TSH 4.05, FT3/FT4 normal), thyroid antibodies negative — no autoimmune flags  
•	Liver enzymes normal, kidney function within range  
•	Vitamin D sufficient, B12 elevated (expected — I supplement methylcobalamin injections)  
•	Total testosterone mid-range normal  
•	Mild low-normal WBC/neutrophil count, rechecking next panel just to trend it  

Nothing alarming, and honestly reassuring given how aggressive the deficit has been.
Happy to answer questions on dosing, timing, or labs.

u/Free-Requirement-777 — 14 hours ago

Should I get another KLOW or straight ghk-cu

Hello, I have taken two vials of KLOW (80mg), taking a third now, probably a week left of it, so 11-12 weeks total. My friend who supplies me is out of straight ghk-cu for now, so it’s either another KLOW from him or straight ghk-cu from a site I know that’s reliable.

I planned on ghk after this klow, but now I am unsure. Definitely think the ghk has had positive effects on skin and hair. Hair likeliest. Tough to say since I take fin and minox.

Left wrist is way better from surgery from 2021 for a scaphoid bone break, wrist had bad mobility and arthritis. Right elbow had bad golfers elbow from lifting. Calmed down SUBSTANTIALLY, can barely tell it’s there. Right knee got pretty rough from quad tendon inflammation from lifting. That’s better, but aggravation persists somewhat.

What do you think, would 15-16 weeks of bpc/tb/kpv be too long?

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u/scarchelli — 11 hours ago
▲ 53 r/Biohacking+1 crossposts

6-Month Transformation (209.4 → 160.6 lbs) | Started Peptides 2 Months In

I’ve been lurking here for a while, so I figured I’d finally share my progress.
Starting (May 2025)
Weight: 209.4 lbs
Body Fat: 32%
BMI: 34.9
Visceral Fat: 17
Current
Weight: 160.6 lbs
Body Fat: 14.6%
BMI: 26.8
Visceral Fat: 9
Total Lost
48.8 lbs from my first InBody scan
55 lbs total from my highest weight of 215 lbs
I trained naturally for the first 2 months of my journey while beginning my preparation for Navy Special Operations. During that time I focused on lifting, running, swimming, rucking, and eating in a calorie deficit.
After those first two months, I decided to incorporate peptides into my routine.
Current protocol has included:
Retatrutide (4mg q4d)
MOTS-c (2mg q2d)
GHK-Cu (1mg qd)
TB-500 / BPC-157 (250mcg q2d)
Tesamorelin (2mg qd)
Any tips are greatly appreciated. I want to be fully shredded by the end of August.

u/No-Hovercraft1995 — 16 hours ago

Please help…triz to what?

I’ve been on trizepatide for a while and now I just micro dose when I feel food noise. Lately I feel lathargic when I take it. I work out and initially on triz I noticed muscle loss. Is there something you recommend switching to? Thank you!

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u/olive_rae1 — 8 hours ago

BAC Water

From the UK, we can't get hospira bac water over here but otherwise I'd love to. Anyway, why do you all say stay away from Chinese bac water. You use their peptides well enough. And in UK I'm 99% sure all the sellers of bac water are just selling china with their own label slapped on it, unless I'm wrong? So yh, what's with all the hate. I'm not paying $8 for one vial when I can get ten for that price

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u/Disastrous-Steak-982 — 15 hours ago

Peptides okay???

I accidentally left my case of peptides out this morning before I went to work. I just got home so they have been out for 10 hrs are they no good or are they still salvageable. I just stuck them back in the fridge. Reta, ghk cu, mots c, and calg.

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u/Nice_Flight6667 — 13 hours ago

TRT and Reta

I am currently taking TRT and Reta for those of you who are also taking both of these my question to you is do you alternate the days that you take them or do you do them on the same days? I use TRT twice a week and went to use Reta two times a week as well, but I don’t know if they should be on alternating days or not

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u/S4LTIZM — 17 hours ago

question about cycling ipa/cjc

Hi there,

Experienced peptide user but was new to ipa/cjc before now. Realizing I stayed on it longer than I should have BUT I also took it at a much lower dose and less days per week than directed. Example, I have been cycling this for 6 months I realized (oops!) but at a dosage of 75 mcg to 100 mcg, the last month I may have gone up to 150 mcg and I've been taking this 2-3 times a week max. I have a 10/10 vial that is still maybe ⅛ full for context.

I'm 45 so....I didn't really want to eff with this class of peptides until I "needed to" (no judgement) - it's a great peptide but I do really want to be able to use this one long term (meaning properly cycling starting and stopping) without burning out receptors. I should stop right? Did anyone else do this long of a cycle and what happened? I'm very thin and was to start, I haven't really put on muscle at this dosage nor was I trying super hard to do that but I experienced improvements in sleep and skin, (my skin was really dry), and improvements in energy maybe, hormones and with autoimmune issues. How long should I stop for to optimize pituitary function? Thanks

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u/Jomobirdsong — 8 hours ago

3 month progress. Seeking advice

26M, 6’0”. Looking for some advice on where to go from here.

I’ve been on reta for about 3 months (missed a couple weeks along the way). I’m currently at 2 mg/week and have gone from 233 lbs to 213 lbs, so down 20 pounds. Overall happy with the progress, but I feel like it’s stalled over the last few weeks.

I know I haven’t been maximizing it. My nutrition has been inconsistent, I haven’t consistently hit my protein goals, and my lifting has been hit or miss.

My goal is to lose body fat while preserving (or ideally building) muscle.

If you were in my shoes, what would you do next?

•	Stay at 2 mg and get more disciplined with diet and lifting?

•	Increase the Reta dose?

•	Add anything else that’s actually worth it?
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u/Free-Ad-9973 — 12 hours ago

Is this safe to pin ? It’s like clumped up at the bottom after recon

I was just about to start ghk I’m not sure if this is normal?

u/genevaluv — 13 hours ago