r/BiohackingU

Would greatly appreciate some advice. 5’10 47yo. 188 to 159. Next steps?

Would greatly appreciate some advice. 5’10 47yo. 188 to 159. Next steps?

So many knowledgeable folks here and I’m hoping to get some guidance from you all. These photos are 188 to 159. Few years ago I was pushing 240. I’ve been heavy all of my life.

I started tirz this April and lost the almost 30lbs from April to now. I focus my diet heavily on protein intake. I’m a tennis addict and in our short Vermont summer I play 5-6 days a week. Usually 90min to 3hours a session. I strength train with my trainer twice a week but struggle to push the strength work too hard in tennis season because the fatigue impacts my match play. I’m super proud of the changes and I feel better and more athletic than ever. I can do sets of pull ups for the first time in my life! Can move so much faster on the court.

I’m still struggling with the lower stomach though. It’s truly a slow process. I appreciate that. Some of the progress pics on here blow my mind though. So my question is what should be my next steps to getting the body to look the way I want?

Do I need to stay the course and be patient?

Crank up the strength training come September when tennis season ends? I could go up 4 dedicated strength days a week easily.

Need to consider any other meds etc?

What would you do?

Sincerely appreciate any wisdom.

Edit. I’m 5’10 and 47yp

u/StudioatSFL — 14 hours ago

What peptides will help raise testosterone?

I had my doctor get my testosterone checked and it came back as:

Total Testosterone: 317
Free Testosterone: 59.9
Sex Hormone-binding Globulin: 35.8

Doc said I didn’t need TRT but I feel differently.

So I started to look into peptides and I’m currently taking tirzepatide 5mg 1x/week. It’s been a month and I’ve lost 11lbs. I started at 219lbs and now I’m at 208. I’m 5’11” and I’m 40 years old.

There’s SO MANY different peptides out there and I honestly have no idea if ANY websites are legit or if they’re scams. So before I find a legit website to purchase peptides I want to figure out exactly what peptides I should try.

From what I’ve researched I’ve been thinking about these peptides to help raise my testosterone:

  1. cjc/ipa NO DAC
  2. Kisspeptin
  3. Gonadorelin

Which one would you guys recommend? Or are there other effective options out there?

I’d love to do TRT out of pocket from one of those online telehealth places but I can’t afford to do that ATM.

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u/RedWoodworking16 — 18 hours ago
▲ 1 r/BiohackingU+1 crossposts

Tesa and bilateral hand numbness

I’ve been on a micro-dose of Reta (12 units) and Tesamorelin (1mg 5 days per week) for 6 weeks now. As I titrated up on the Tesa I started getting hand numbness during sleep. I know this is a common side effect but does it hasn’t gone away, it’s every night now. Has anyone else experienced this and what did you do about it?

Could it be quality of the peptide?

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u/HopefulSpeech4842 — 21 hours ago

reta to triz

personal info: 19, female, 5’5” and 125 lb

i did reta for like 3 weeks at a 0.5 mg dosage but then my heart rate like sky rocketed so i thought about getting on triz instead. i was wondering if the dosage is like basically the same?? like i could also do 0.5 mg of triz?

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u/salmipantz — 2 days ago

Are these Reta20 vials looks okay?

Hi guys do you think they look okay? They are solidified as cylinders not powder like and i am not sure but top part looks shiny as well. I am scared of humid in it since it looks shiny.

u/patrona_halil — 2 days ago

Are there any substances that substantially improve vision, hair, overall physical performance and aesthetics?

I know taking multivitamins “improves” all of the mentioned categories but Im looking for something that offers more ROI. I’ve taken peptides before , however most of the benefits from them feel pretty mid. I’m thinking about hopping on test to gain some more muscle but I am worried about sides such as hairloss and dont like the idea of pct or lossing all the muscle gained cycling off. Whats even the point of spending a lot of money on roids just to go bald lose all your hair and have zero test?

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u/Valuable_Luck_946 — 2 days ago

selank/semax vs na selank/max vs na selank/max amidate vs adalank/max

heyo,

i was curious what is the difference between these. I tried researching it on here and most posts are 11 years old. So i figured i would ask again for perhaps better answers.

anyone who used different kinds and compared? intranasal vs subq injections differ per or are all the same?

so far i read that each one is more potent than the other and that adalank/adamax are the strongest. But some people felt nothing with adalank/max nor na /na amidate.

thanks.

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u/espresso_maniac — 2 days ago
▲ 3 r/BiohackingU+2 crossposts

Test?

I want to add about 10lbs of muscle could I do 1 16 week testosterone cycle and go back to not being on it after doing PCT? I feel I am at my natural limit. Been lifting for 5 years and progress has slowed significantly in the last 2

u/liftingfireman — 2 days ago

Grey In the UK?

Has anyone from the UK gone grey and bought directly from a Chinese vendor? I have recently moved to the UK, and am in need of new batches.

However, I am a bit scared of customs and of my package being seized. Has anyone from the UK had any issues with their packages from Chinese vendors lately?

I don’t know why I’m so paranoid lol. I read a dude who had cops show up to his door? Like wtf!

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u/withivi — 3 days ago
▲ 0 r/BiohackingU+1 crossposts

No more gray for me.

Over the last 4 months I have spent hundreds thousands dollars on glp's off the gray. I've not lost the weight I thought I would lose nor have I even come close to the weight my friends have lost. I walk nd go to the gym, and I'm always in a calorie deficit. In 4 months I lost only 14 lbs. I have been consistently on Reta. My first batch was from Oath I lost 10 lbs in two weeks. Then I ordered from the gray. It was trash. So I bought another batch and it was trash. I am on 10units and I still have food noises like crazy. It's only helping me maintain not lose.

I said all of this to say. I need help!

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u/False-Truths — 3 days ago

Reta and MOTS-c

Hi folks. 32-year-old woman with T2D and obesity here. I’m in my first month on Reta, and the adaptation has been a bit difficult so far, mainly because of a lot of fatigue.

I’ve seen that quite a few of you are adding MOTS-c to improve energy levels and mitochondrial function.
What protocols are you using? What doses? Any side effects? What are your overall impressions? Any dos and don’ts?

Thanks!

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u/No_Bowler_2982 — 3 days ago

Could transdermal peptide delivery make sense for people who want to avoid injections?

I’ve been looking into different peptide delivery methods lately, and the transdermal side seems especially interesting. A lot of people are curious about peptides but aren’t necessarily comfortable with regular injections. If transdermal delivery could offer a reliable way to administer certain compounds, do you think that would make peptides more accessible to a broader group of people? I’m curious whether people here see patches and other transdermal options as a meaningful direction for biohacking, or mostly as a convenience feature unless the delivery data becomes stronger.

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u/AbbreviationsNice771 — 3 days ago

Bringing research triz to prague from U.S.

I’m a U.S. student who will be staying in Prague for several months for study abroad, and I’m trying to figure out the Czech rules before I travel.

I have a vial of tirzepatide purchased from a U.S. peptide supplier. It is labeled “research use only / not for human consumption” and is not pharmacy-dispensed Mounjaro. I would only have like two personal-use vial and would not be selling or distributing it.

I know pharmaceutical tirzepatide (Mounjaro) is legally available in Czechia by prescription, but I’m specifically wondering about research-grade tirzepatide.

Does anyone here know:

  • Is simply possessing a research-grade tirzepatide vial legal in Czechia?
  • Can I legally bring one vial with me through Prague Airport from the U.S.?
  • Has anyone actually traveled into Czechia with a research peptide?
  • Would Customs confiscate it, or could there be more serious consequences?
  • Is there a Czech authority (Customs/SÚKL) that I should contact for written confirmation?

I’m trying to make sure I’m following the rules before I travel rather than finding out at the airport.

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u/salmipantz — 3 days ago

Recently sides (Reta/ARA-290/MOTS-C

So I've been pinning Reta for x5 weeks now, went from 2mg to 3mg last week. At that time I also started ARA-290 4mg daily and I pinned 3mg MOTS-C day one and then 4mg last Thursday and Friday having not done any Tuesday.

I started both last Saturday.

I ran a strange fever last Monday, and all my joints and my "skin" started hurting around Thursday, and it has increased in intensity. I completely stopped the MOTS-C and ARA-290 on Saturday, last dose Friday.

What in the hell is happening to me? Tha pain feels like needles when anything touches my skin and walking really sucks.

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u/DoubtEmbarrassed5709 — 3 days ago
▲ 36 r/BiohackingU+2 crossposts

Did I just ruin my hair with MT-2?

Hi, natural redhead here! I started MT-2 (2ml BAC, built up to 20 units a day) for the entire 80 ML vial. I noticed my body hair turning a greyish black and didn’t think much of it, ordered a new vial, and then I noticed my roots are coming in a gray black as well. I actually just threw out a whole brand new vile, as I love my hair colour. I’ve been off for two weeks now.

I still notice greyish roots. Is this something that might be permanent??? Will my colour grow back in? **I know this is very minor so far** but I’m quite nervous so reassurance would be awesome!

u/Temporary-Peanut6707 — 4 days ago

Beginner

Hey all! I am new to biohacking but am super hopeful about this as the future of holistic healing! I currently inject KLOW 10mg/10mg/50mg/10mg total 80 mg reconstituted with 2 ML BAC, 10 units per shot. I’ve been taking this for a month and feel pretty good on it! I’ve been taking semaglutide for over a year now. Off and on. I also started TA-1 5mg reconstituted with 2 ML BAC, 40 units twice per week. I am using these for systemic inflammation, pain, immunity (I have hashimotos) and the cosmetic effects are a plus as well. Is anyone on this stack as well and what are your thoughts? Does anyone use these for inflammation and immunity purposes and do you recommend staying on this regimen? What are some other peptides that may help me heal? Thank you!!

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u/Slooththehousedown — 3 days ago

if retatrutide becomes fda approved and regulated what happens to the grey market pricing?

Stocking up doesn’t seem wise when it’s shelf life is 3-4years before recon

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u/Negative_Sprinkles77 — 6 days ago
▲ 5 r/BiohackingU+1 crossposts

Coming off of Reta!

I have only managed 6 weeks on Reta and I’ve frustratingly had to come off of it. I titrated up slowly over 6 weeks up to 1.5mg which I know is still a low dose but the side effects have been unbearable and I’m no longer able to just “push through” it. I didn’t have any appetite suppression, in fact, quite the opposite, I’ve put half a stone on and the constant distended bloating was the icing on the cake for me.

I literally would wake up every morning looking 6 months pregnant, it didn’t matter if I had a bowel movement everyday, exercised, or avoided foods that trigger bloat, and by the end of the day I looked like I was ready to give birth. The pain from the bloating completely radiated through my back, the pain and discomfort has been extremely depressing.

I am just so disappointed because hundreds of you rave about how well it works for you…I very much feel like “why not me” 😩 So I’m going to have to try and find the money to go back on mounjaro as this massively helped with any inflammation I had. I just feel so disheartened, has anyone else had to come off of Reta due to unbearable side effects without having any benefits?

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u/Beehive-honey — 5 days ago
▲ 535 r/BiohackingU+3 crossposts

9 months of GLP and peptides

Started at 245 lbs 44 percent body fat on 1st Dec 2025. Currently at 166 lbs 18.8 percent body fat. Started with triz titrated from 2.5 to 10. 10 was too much for me so went back to 7.5. Added cjc+ipa 12 weeks back. That helped me with some good sleep. Currently at 5 mg triz and aod. Aod helped me break the 20% body fat. I was struck there for 4 weeks. Planning to hit 15 percent body fat at 170 lbs by December 2026. Fingers crossed

u/Bright_Register6812 — 6 days ago