14 months on Zepbound, hit my goal, doctor and then I agreed to stop. My first two weeks felt fine, by week four the food noise was back in a way I hadn't felt in over a year.
Up 4 lbs now:( not panicking but also not pretending it's not happening.
Seriously looking at Foundayo as a maintenance option. Guide me in!
11 weeks on. Food noise seems to come a waves. Ok most of the day, then suddenly wanting to eat everything. Thankfully, now that i dont store snacks at home, i simply dont have a source to binge on. But definately recognise it, and try and distract thoughts. Missing the MJ effect of just obliterating that desire. Total weight gain = 1.5kg since stopping. Some of it intentional. On 2900 cal atm (54 M 177 cm 74 kg). Miss being super lean (ie at end of MJ), but lifestyle wasnt sustainable. I feel chunkier, but prob dont look it. Eating has changed for me. Start w a high prot breakfast. Then a big lunch box that i take to work, which i split eat through the work day - 11am, 1pm and 3pm (ish). Still maintaining 8k steps, 3 resist training a week(just dumb bells at home). And yoga 3x /week - just at home w my own routine.
Had big weekend event just past. 2kg weight gain. And eventhough i knew that the science said it was water and salt, so much panic and anxiety in my head. 3 days later back to base line.
So far, so good. I think. Apparently 1st few months are toughest. Hoping its coming to the end of it!
Dietitian here. I've worked with GLP-1s for many years and have published research on them. My focus is the long-term side: maintenance dosing, tapering, and for those who want to try it, offboarding.
I've built a program for that phase and I'm looking for 10-15 beta testers in exchange for honest feedback. Free, no upsell.
If you're currently on a GLP-1, near your goal weight, and thinking about what comes next, DM me. I can send a short video of what's in the program, share more detail, and point to my work if you'd like to check me out first.
Let me preface this by saying I have lost 100Ilbs on MJ and it’s transformative. I work in central government with NHS, politicians and policy leaders. I’m frankly getting sick and tired of some Doctors in-built prejudice. E.g. today a doctor said that prior to surgery, they were shocked by a patient taking GLP1 who had stomach content from seven days ago, and that evidence showed people put at least 20% of the weight back on and everyone had to be on GLP’s for life. She was also very agitated about muscle loss being unavoidable and that poor people who lose weight won’t keep it off because of ultra processed food and lack of opportunity to exercise (her point being you can’t prescribe the drugs if you don’t address the other factors). A year ago I said to a room full of orthopaedic surgeons that they should prescribe GLP1s for all weight related/exacerbated conditions. I was laughed at, but those same clinicians are now saying the exact same thing so it is possible to change peoples minds. By the way the NHS pays between £6000 and £14,000 for a knee operation.
I would love to know the thoughts of you lovely people with actual ‘ lived experience’ and any ideas of how I can combat these attitudes next time I encounter them.
Was on sema first, didn't really take for my body. Switched to tirz, dropped 44 lbs over about 6 months. Felt unstoppable. Then around month 3 I started losing serious muscle. Bone too, I found out later. Nobody had warned me about either.
I figured I'd done the hard part, so I stopped the med. Six months off, thinking I'd keep what I'd built. Gained all 44 back. It broke me. Watching it come back like that with no off switch in my brain. Done the thing, then undone the thing.
Back on now at a maintenance dose. Second time around I had to actually learn the nutrition piece. Eating my protein daily, lifting, actually sleeping. The medication does its job. Everything else was on me to figure out. I'm 45 and I feel better than I did at 30.
Quick PS, hope this is okay to post here. Today there's an AMA with Ashley Koff RD (super well known RD) running on Ozempic sub from 11am to 2pm PT, on the nutrition side of all this (maintenance, muscle, bone, hair, food noise, the stopping question). If you have anything you've been wondering about, drop it in there.
Anyone else here gone through a regain after stopping?
So in Dec 2024 I went on Zepbound my initial weight was 201lbs (heaviest I've ever been) and as of today I weigh 137lbs. Now I'm figuring out where to go from here? Without getting too deep into I have a lot of health issues one that specifically needs food restrictions that I've been doing since birth. Before Zepbound I was struggling with basically two diets ( Medical and Weight Loss) and I only saw weight loss progress if I was doing the weight loss/ exercise diet in extreme and unhealthy ways.
So now I'm in maintenance territory but I want to come off injection and maybe do a pill and I heard of the Wegovy pill and I believe metformin is another option but I'm so scared that it's not going to be as affective and my food noise and craving are going to come so I want to know what everyone's experience is and if they have any recommendations I should talk to my Zepbound dealer about. Like Zepbound was so freeing with the way I had ZERO craving not even a tummy gurgle and I would like to keep that up so I can not be in this controlling battle with food.
My last shot was around the end of April. I’d been on and off tirz for a little over a year and finally agreed to stop refilling after having a long and hard conversation with my partner about finances and possible long-term side effects even thought I’m not at my GW yet (40 down, ~30 away). She’s worried that the cons outweigh the pros. We both saw articles on long-term (bad) effects on the heart once you come off glp-1.
I’ve always had trouble keeping the weight off no matter what. Starting tirz was the first time I felt like something worked. Now that I’ve been off a while, I feel the confidence slipping away, especially the days when I don’t feel motivated to keep up with my work outs.
How do I keep it off? The food noise is bad but I do my best to keep it at bay. I try my best to watch what I’m consuming.
I feel somewhat defeated and I’d love some guidance.
A little backstory I was on reta for eight weeks I was on the dose of .5
I didn't really have any side effects while on the medication other than the occasional bloating which went away after taking gas X ECT I got extremely ill one night and ended up going to the hospital by ambulance where they ran all kinds of tests and did an x-ray and a scan pretty much told me I still had food in my stomach but everything looked fine I ended up coming home and was okay for a few days woke up 3 days after first hospital visit and felt okay so started doing a lot of stuff around the house instantly felt like I was going to pass out or throw up or both so ended up going back to the hospital all my blood work everything was fine this has been an ongoing battle but it is getting better today is 23 days since my last shot which I quit cold turkey and a lot of my GI issues have subsided I still will get slightly nauseous every now and then or every few days for just a few hours but I have pretty much been on the extended BRAT diet for almost two and a half weeks I have added in some lean proteins ECT and my pcp says thats fine just to slowly reintroduce things as the shot leaves my body is anyone else experiencing things similar to this I'm also noticing now that some days I'll be really hungry and some days I will be hardly hungry at all which from what I've read is normal as the shot is leaving your system I was waking up in the morning feeling kind of shaky and weak and just out of it a little bit that is becoming better as well just looking for anyone that might be going through anything similar it's always good to have some support
I have an appointment with my anesthesiologist next week, so I will be discussing this with them and following their medical advice. I’m not looking for medical advice here - more for personal experiences, reassurance, and things I may not have thought of.
I’ve been on Mounjaro for about 7 months. My highest dose was 6 mg. My last dose was May 2, so it has been a little over 2 weeks since my last injection. I was traveling during that time, so I didn’t inject while away.
I’m now back home and have a laparoscopic surgery scheduled for June 10, which is about 3 weeks from now. According to Shotsy, my estimated medication level is currently around 1.47 mg.
I’m almost at my goal weight, so my instinct is to stay off Mounjaro until after surgery, especially because my levels are already quite low. My main concern with restarting now is not the medication level on surgery day, but whether even a low dose could trigger side effects again - nausea, constipation, reflux, delayed gastric emptying, etc. - and complicate anything before anesthesia.
The only alternative I’m considering is taking one low dose of 2.5 mg this week, then stopping again until after surgery. I would not continue weekly injections before surgery.
For context:
SW: 75 kg / 165 lb
CW: 57 kg / 125 lb
Height: 163 cm / 5’4”
I didn’t lose or gain weight while traveling, but eating was irregular and a bit “weird,” so I’m not sure yet what my appetite will be like now that I’m back to my normal routine.
I’d really appreciate hearing from people who had surgery while on Mounjaro/tirzepatide or who paused and restarted around surgery. Did you stay off completely? Did you take one last low dose weeks before? Did restarting after a pause bring back side effects for you?
Again, I’ll be asking my anesthesiologist next week and following their guidance — I’m just trying to think this through before the appointment.
Did anyone get constipation when stopping a GLP1? If so, how long did it last? Didn't expect this one!
** I don’t hear much about ppl getting wls AFTER glp-1s I’ve searched a few subs and nothing concrete
I’ve been on compounded tirz for about 8 months now and I’m down 45 lbs. from 280 to 235 , 5’1 F 23 No major lifestyle changes, though I did move out of my parents house so a lot of my stress eating subsided naturally after gaining a sense of agency over life.
I have very light exercise, I walk dogs 3x a week at my local spca for a few hours and I love it. I’m trying to incorporate weight training now to help as well.
About a year before I started tirz I was approved for WLS and even had a date set. About 1 week to my surgery date my parents sat me down and told me not to do it and that I was too young and I still had the ability to lose weight on my own and that surgery was permanent. I was 22 at the time.
I’m now 23 and have since moved out and I’m not sure if I want to continue with tirz long term. Though im responding relatively well with no major side effects, I’m still thinking if I’d really want to take this long term. I see things like rebound weight gain after stopping and they are concerning of course. Especially for me give that I haven’t done anything super intense in terms of lifestyle changes that would mitigate that. I also am just not the best at taking medication. I often sometime stretch my doses 11-12 days apart because of my adversion. Nonetheless tirz has helped me so much, I feel more confident almost 50lbs down I no longer need a seatbelt extender on flights and I can cross my legs.
My goal is to be in the 155- 170 range. So I still have some ways to go. Now that I’ve moved out I am considering the surgery in the future, maybe in the next year or so? I haven’t found much about ppl getting the surgery post glp, it’s usually the other way around. Can anyone pls share their experience??
Has anyone quit for pregnancy? So worried about gaining it back and everyone else tells you that you will so it’s extra discouraging. Any tips/motivation/etc would be helpful. Does the rebound noise level out over time?
Even if you’re not pregnant, if you’ve maintained I’d love to hear your story.
49 year old, female, post menopause, with Hashimotos. Have been pretty fit and healthy my whole life. Nothing obvious changed in my life but all the sudden I had put on about 15 pounds in what seemed like overnight. This may sound like vanity weight but I am 5 ft tall and that’s a lot for my petite frame! I also was told to get on cholesterol medication for extremely high cholesterol and could not drop the weight. Started microdosing February of 2025. My goal was 12-15lbs. I ended up dropping about 18lbs and have subsequently put on at least a pound of muscle. My starting dose was 1.25 mg and I never went over 2.5 mg. Am currently maintaining at 2 mg. I lift heavy weights, eat protien and sleep! I feel strong and back to myself!
I came off mounjaro months ago and I am still absolutely freezing all the time. Electric blanket at night, thermals in the day. My BMI is 28ish so I'm not skinny (although happy with where I've landed), there's still some meat on me! But I am shivering. Will my body's thermostat ever rebalance?!
Its been almost a month i am on sema 5mg .. i hv lost 20 lbs but i feel very tired with constant cravings and food noise. Is it normal? Do i have increase dose?
After coming off a GLP1, how long did it take for your weight to settle down after the fluid/inflamation returns please?
Edit: I tapered down very quickly.from the highest dose. The weight gain started almost immediately - it's been about 12 weeks of gain and I mnlw from my calories the majority cannot be fat
I’ve been trying to space out doses of 5mg for several months now. I started zeroing in late July 2024, and stayed at 5mg most of the time. I hit my goal weight in January, even went a bit below after trying a few doses of 7.5 (but didn’t like it), and have been trying to space them apart since February. I was at almost 2 weeks between doses and while my weight went up a few pounds, it was still below goal. I’m closer to 3 weeks apart now but struggling with food noise. I know I’m eating too much, which some of the hunger is driven by me adding in more running to my exercise, but it’s really making me realize I don’t have any good coping mechanisms for the food noise.
For background, I was never one who struggled with my weight until after I had kids, so it’s only been the last 8 or so years where I’ve been overweight. I’m 41, 5’7, and trying to maintain between 140-145. My starting weight was just under 180. I was really hoping that staying on a low dose for a short amount of time would help me be able to transition off more successfully.
What worked for you in order to stop taking it entirely and maintain your loss?
Recently found out I’m pregnant so have to stop using my GLP1 after a year of being on.
The pregnancy is definitely wanted but of course I’m nervous about all the weight I’m about to regain and undo all my progress. I gained so much weight my first pregnancy, I want to make sure I don’t repeat the same mistakes I did the first go around.
Any mommas out there in the same boat or have been in the past? Did the GLP1s work again after the pregnancy if/when you went back on?
Am I the only one who kept losing a few more pounds after I stopped my weekly shot and have not taken a dose in over 6 months and still have not gained weight ? Like I’m seriously not trying to be funny. Same thing happened with my sister. I was telling my mom. It’s like it fixed something in us that was broken. with being on zepbound for 10 months I lost 55 pounds then lost an additional 5 pounds over a 2 month period after I stopped. I didn’t even need to lose the 5 extra pounds I’m 5’6” and sitting at 126. I went down to 125 when my weight loss finally stopped. In fact I want to gain 5 more pounds. Has this happened to anyone else ? I see a lot of people talking about gaining back the weight. I was fully prepared to continue with this for a lifetime if needed with maintenance because of everything I read, but I’m not getting that experience. Anyone else out there like that or know someone like that is something wrong with me my sister like I’m actually kind of concerned in a way. Is this normal?