After trying basically everything, here's the combination that finally fixed my Mounjaro constipation
I've struggled with the GLP-1 constipation for over a year, and I've tried it all. Psyllium fiber made things worse because I wasn't drinking enough water. Senna worked but gave me cramping and I worried about dependency. Linzess was too strong and unpredictable.
But what finally worked for me was a two-part approach that my gastroenterologist suggested: a capful of Miralax (polyethylene glycol 3350) mixed into my morning coffee every single day, even if I felt fine, plus one 200mg capsule of magnesium glycinate at night. The Miralax draws water into the bowel, and the magnesium helps with muscle relaxation and motility. It took about a week to become regular, but now I go every morning without fail and without cramping. For anyone else who has been suffering, what combination has worked for you?