So this is the third time I'm watching it. I stopped watching it because of the trauma the characters go through.
However, this show is just too good so I'm rewatching it. Oops.
They're highly effective for insomnia but it seems like no provider is willing to prescribe them since they're so rare.
However, I think they could really help me.
I've tried 1.5mg Xanax, 4mg Klonopin, 4mg Ativan, and right not I'm on 40mg diazepam which helps sometimes but not always.
Could flurazepam, estazolam, triazolam, or quazepam help?
Ok, so I know that he's taken a break from the spotlight, but what do you think he's actually doing now?
After Henry Danger ended, he became a producer for Danger Force.
Once that ended, he went on a Podcast with Jake Short & Bradley Steven Perry where he talked about quitting social media and going away from the spotlight since it was unfulfilling.
He last posted on instagram in 2024.
We saw him in the Henry Danger Movie in 2025.
And that's it.
He started Creator Edge Media in 2018 but that's not active anymore.
He opened up a restaurant in his hometown but I'm not sure what the status of that is or if he stills works there
I wonder if he's doing any work or if he's taken a permanent hiatus from the spotlight. What do you guys think?
Either way, being a child star can be toxic and I hope he's doing well.
For context, I’m prescribed a stimulant (methamphetamine, yes it’s a prescription drug).
I seldom take it but when I do it works quite well. The only downside if that there’s a crash in the evening when I talk it.
Do you have any tips/supplements/medication that prevents that? I feel like some people take vitamins, or they drink water, or they take anticonvulsant.
There’s so many methods but none of them help.
Hey guys, this is for anyone who's worked at IQVIA. Specifically, people who came in as a CRA I at IQVIA. How much is the salary increase for the CRA II promotion.
I've heard that internal promotions/raises aren't that big. Can anyone who's gotten promoted internally at IQVIA tell me what position you were at, which position you got promoted to, and how much the salary increase was?
I’ve seen a lot of CRCs (and sometimes CTAs) get frustrated when I ask them to do tasks or they can get antagonistic.
Obviously the reason is because as a CRA most times when we ask for something it’s because upper leadership asked for it or we’re just trying to help you get back into compliance.
As a previous study coordinator, I understand how challenging the job can be so to and CRCs or CTAs out there just know that we are so grateful for all that you do and you’re a very important part of clinical research.
Here’s a wonderful basket of fruits.
Here you see some plums, kiwis, blueberries, and raspberries.
I feel like the plums resemble Ren. The crimson color represent her pretty but evil nature.
The raspberries resemble Akito. The brighter red color represents pain and hope - which is a perfect description of Akito.
The kiwi resemble Shigure for no other reason than it kind of looks like the clothes he wears.
The blueberries resemble Yuki because I feel like his aura is a dark blue. Not that that’s a bad thing.
Thanks for listening 😁.
Since when is remote monitoring “half the industry”. Thats ridiculous.
In-house CRA roles are scarce and make up <5% of all CRA job postings.
Most CRA job postings require travel and on-site monitoring.
Sure, remote monitoring was more prevalent after 2020, but it’s gone down a bit.
Hi guys,
I have stage 5 treatment resistant depression, and I'm wondering what options I have.
I’ve tried SSRIs, SNRIs, TCAs, MAOIs, ketamine, ECT, rTMS, psychedelics, neurofeedback, and dTMS.
Of them, I didn’t do a complete trial with ECT and dTMS.
For ECT I did 4 sessions 5 years ago My seizures were extremely long and the first two had to be stopped with midazolam. The next two were very long but stopped within 80 seconds. ECT made my depression worse and gave me profound anhedonia and sexual dysfunction for eight months after. The ECT psychiatrist said that even though that I did 4 sessions, that more wouldn’t help.
My current psychiatrist says that a full course of 6-12 sessions may be more appropriate and that me feeling worse was just because of the seizures, but I feel like given how bad it made me feel that doing a full course isn’t worth it/won’t work?
For dTMS, the psychiatrist did a qEEG and found that my frontal cortex was overactive. She prescribed an inhibitory protocol using the H1 and H7 helmet. It made my mood feel worse and she stated that the standard FDA protocol wouldn’t help either.
I also tried psychedelics (LSD) and it didn’t help and I had a bad trip with no visuals.
My questions are:
Hi guys,
I have stage 5 treatment resistant depression, and I'm wondering what options I have.
I’ve tried SSRIs, SNRIs, TCAs, MAOIs, ketamine, ECT, rTMS, psychedelics, neurofeedback, and dTMS.
Of them, I didn’t do a complete trial with ECT and dTMS.
For ECT I did 4 sessions 5 years ago My seizures were extremely long and the first two had to be stopped with midazolam. The next two were very long but stopped within 80 seconds. ECT made my depression worse and gave me profound anhedonia and sexual dysfunction for eight months after. The ECT psychiatrist said that even though that I did 4 sessions, that more wouldn’t help.
My current psychiatrist says that a full course of 6-12 sessions may be more appropriate and that me feeling worse was just because of the seizures, but I feel like given how bad it made me feel that doing a full course isn’t worth it/won’t work?
For dTMS, the psychiatrist did a qEEG and found that my frontal cortex was overactive. She prescribed an inhibitory protocol using the H1 and H7 helmet. It made my mood feel worse and she stated that the standard FDA protocol wouldn’t help either.
I also tried psychedelics (LSD) and it didn’t help and I had a bad trip with no visuals.
My questions are:
Hi guys,
I have stage 5 treatment resistant depression, and I'm wondering what options I have.
I’ve tried SSRIs, SNRIs, TCAs, MAOIs, ketamine, ECT, rTMS, psychedelics, neurofeedback, and dTMS.
Of them, I didn’t do a complete trial with ECT and dTMS.
For ECT I did 4 sessions 5 years ago My seizures were extremely long and the first two had to be stopped with midazolam. The next two were very long but stopped within 80 seconds. ECT made my depression worse and gave me profound anhedonia and sexual dysfunction for eight months after. The ECT psychiatrist said that even though that I did 4 sessions, that more wouldn’t help.
My current psychiatrist says that a full course of 6-12 sessions may be more appropriate and that me feeling worse was just because of the seizures, but I feel like given how bad it made me feel that doing a full course isn’t worth it/won’t work?
For dTMS, the psychiatrist did a qEEG and found that my frontal cortex was overactive. She prescribed an inhibitory protocol using the H1 and H7 helmet. It made my mood feel worse and she stated that the standard FDA protocol wouldn’t help either.
I also tried psychedelics (LSD) and it didn’t help and I had a bad trip with no visuals.
My questions are:
Kyoshi and Yangchen one on the most overpowered Avatars in the franchise (not the most powerful).
Kyoshi casually split an entire peninsula from the mainland and created Kyoshi Island, while also living for over 200 years and displaying some of the most devastating large-scale bending feats ever seen.
Yangchen’s power is crazy. Her airbending is so powerful that it could move the entire sky and create literal natural disasters like hurricanes.
In my opinion, Aang is the most powerful because he learned all the elements so fast and we don’t see him in his prime, but Kyoshi and Yangchen don’t think twice about using brute force to beat their opponent.
With the exception of Aang, Kyoshi and Yangchen are in a tier of their own in terms of raw power.
I have anhedonia and have tried MAOIs, ECT, Ketamine, TMS, EMDR, Neurofeedback and all other medications.
I wonder if psychedelics will help? I see a bunch of clinical trials for them. However, I know there’s risks of worsening depression, depersonalization, and HPPD.
Has anyone with my level of treatment resistance tried psychedelics and have they helped you specifically with anhedonia and dulled senses?
I forgot to say I tried LSD years ago. There's no way of knowing that it was LSD but I'm pretty sure it was as I had a panic attack with no visuals. So I feel like they won't help but want your guys' opinions.
I have anhedonia and have tried MAOIs, ECT, Ketamine, TMS, EMDR, Neurofeedback and all other medications.
I wonder if psychedelics will help? I see a bunch of clinical trials for them. However, I know there’s risks of worsening depression, depersonalization, and HPPD.
Has anyone with my level of treatment resistance tried psychedelics and have they helped you specifically with anhedonia and dulled senses?
I forgot to say I tried LSD years ago. There's no way of knowing that it was LSD but I'm pretty sure it was as I had a panic attack with no visuals. So I feel like they won't help but want your guys' opinions.
Ok, so my Nickelodeon/Disney days came to an end around 2014, right when this show started.
I started watching it about a month ago and in my opinion it's the last good Nickelodeon show after 2014.
iCarly, Victorious, Zoey 101, Drake & Josh all came to an end before 2014 and in my opinion Nickelodeon's prime ended.
However, this show brought it back. From 2014-2021 this show and Jace Norman was the face of Nickelodeon. Some people say that 2016 was Nickelodeon's prime, and I respectfully disagree, but this show brings it close to its prime.
After the show ended Jace appeared in a few episodes of Danger Force (I don't like that show), and in the movie (it was good but open ended). We didn't get a good ending to Henry Danger. It was left open ended like the iCarly reboot. The movie would've been great if Captain man didn't appear at the end.
He kind of faded away from the spotlight and went into entrepreneurship and producing. However, it seems he's taken a hiatus from everything and won't be coming back. It's so sad because I'm such a huge fan of his and I don't think he's working on any projects right now. Regardless, I'm sure this is good for his mental health because being a child star on Nickelodeon (with Dan Schneider) probably wasn't the best thing. He mentioned he had mental health issues and I hope he's doing well.
Edit: I think he wanted to star in more grown up shows and movies (referencing the Golden State Pilot which left me shook) but didn't get his big break like other Nickelodeon/Disney stars.
I wonder what he's up to these days. What do you think?
Does anyone know why AstraZeneca's CRA and Global Study Manager Salaries are the same?
Ok, so as a CRA I feel like I have a good hold on most of my job tasks - except for TMF/ISF reconciliation.
Basically, I pull the TMF docs from a site and check it with the ISF and see what's missing. However, I find it to be very time consuming and worry that I might miss something given the sheer volume of documents.
Do you guys have any tips on how to streamline this? And if I happen to miss documents, would anyone realistically find out? I know that's not the best way to think about it but I'm just curious.
Spy x Family is one of the greatest anime of all time. I just finished the show a week ago.
Spy x Family combines action, comedy, romance, and drama into a cohesive storyline. The premise is so unique entertaining, and it's a surprisingly heartfelt story about loneliness, found family, and people learning how to care for one another.
Loid is one of the best modern protagonists and a very well written character, Anya is just iconic, and Yor is the most hilarious and deadly character on the show.
It may not be as complex or deep as other anime, but the show is perfectly executed as a slice of life/action anime simultaneously.
The only bone I have to pick with the show is that 1) I want Loid and Yor to confess their love 2) I want them to know their true identities and 3) I want all of them, but especially Loid, to find peace.
Ok so at the end of SpyxFamily Melinda Desmond, Damian Desmond’s mom is introduced.
Her character is so interesting. She seems like a normal woman at first but you see she almost has a split personality. She’s warm and inviting at first but then she shows dark, vindictive sides to herself as well.
Especially towards Damian.
I’m not all that surprised as I’d expect the spouse of someone with so much power to have a duality to their personality.
I feel like the answer is obvious, but do you guys know why that is?
I know it has something to due with the fear of Donovan Desmond and his sudden personality change, but I still can’t understand why she’s so extreme.
Not that I’m complaining, she’s one of my favorite characters.