u/Daniel-Plainview96

This isn’t good. I’m generally a healthy person. Taking 75mg. Been on nardil about 3 months.

First couple months really didn’t have a problem with overeating. Mild cravings but nothing insane.

Did a keto diet for a few weeks up until last week, not for losing weight but losing the water weight/edema associated with nardil.

Well, last week, after a stressful day, I went and picked up some donuts. Said fuck it. Ate all 12. Since then I’ve been doing the same thing every night, and some days I’ve been eating as much as 10k calories, making myself sick but my mouth/body keeps wanting more.

Never dealt with binging on food like this. It’s bad. As you might imagine I’m gaining weight pretty rapidly. It’s like once I put something with carbs in my mouth, I just want more and more.

What are we doing to deal with this?

29-year-old male.

Used to hyper-fixate on testosterone as a teen, convinced low T caused every problem in life. These days I don’t really care, but of course, all else equal, I’d rather have higher levels.

(Obviously not the end-all-be-all of hormonal health.)

For reference, the standard range for total testosterone in adult males varies, but it's generally around 250-900 ng/dL. Mostly out of curiosity, periodically, I get my levels tested (I'm a certified data-fiend) and I usually land around 250–400 ng/dL. 500 at best. What are ya gonna do?

Well so recently I had bloodwork done to check my liver and kidneys on Nardil. Asked my doctor to include a hormone panel. If anything, I expected to see my testosterone levels in the gutter what with the Nardil insomnia.

Instead, it was nearly 800—easily my highest reading ever! Hooplah! My usually-high estrogen was also near the low end of normal. Go figure.

No idea whether Nardil caused it, but if so, my guess is that the huge reduction in stress has finally let my hormones sort themselves out... that still seems dubious though.

Niche question, but has anyone else had this same experience—or know what might explain it?

Thanks

Recently realized my life long heavy duty fear of spiders has lifted quite a bit since starting nardil. No reaction to small to midsized ones and very large ones only mildly disgusted.

I did encounter the largest one I’ve ever seen in North America recently—some genetic abomination supposed to be a wolf spider, speedy, probably a result of Chernobyl, fond of hide and seek (continuously darting behind things I had to pick up)—So I’ll admit, that guy still had me a little nervous…

But the rest of monstrosities I cross paths here in the pnw ain’t no thing.

And this is coming from someone who used to panic to the point I’d stop breathing when I saw a spider.

Relatively minor win, but goes to show how well this stuff helps with anxiety.

Feel free to roast me

So you’re not supposed to let nardil get hot. I know this, but I had some I’d left in my hot car, and when I realized I’d forgotten my dose, I took the car-nardil (car’dil) on my way to a function. Thought at worst it just wouldn’t work. I’ve done this twice, both times the same thing happened, but ofc I didn’t realize it was the heat-expired/denatured nature of the nardil till it happened again the second time, earlier today.

Within 20 min of taking, my face got all red, my cheeks, and all around my eyes. I looked like an opiate addict or someone experiencing an allergic reaction. I looked like an anemic Victorian era child, except somehow more disturbing, like I had face paint on. During my meeting people kept looking over at me. My face felt flushed but I didn’t realize how bad it was till I checked my reflection. Woulda been embarrassed except nardil makes me not care haha.

I was under the impression Nardil simply lost potency if you let it get hot. Clearly there’s a little more going on.

Anyone else experience this?

The pills also tasted sour btw, absolutely nasty.

Thanks

This might be an unusual post, and sorry if it’s TMI, but it’s been bothering me lately. It’s more of a psychological question than a skincare one, and I’m wondering if anyone else experiences this.

Ever since I first started getting pimples as a teenager, I thought you were *supposed* to pop them. By the time I learned you weren’t, the habit was already deeply ingrained.
The problem is the job doesn’t feel “done” till I’ve gotten *everything* out—which usually means damaging the skin and leaving a red mark that’ll take days to heal. It’s not enough to get the pus out; I compulsively squeeze until the hard “core” comes out, sometimes even until the fleshy lining of the pore does too…

If I pop one, it’s difficult not to pop the rest. I’ll tell myself it’s the last one, then suddenly I’m back in front of the mirror squeezing. It honestly makes me feel like a frenzied drug addict picking at their face. If I notice a pimple that looks or feels poppable, it nags at me until I eventually give in.

What’s strange is I don’t have this kind of compulsive, self-destructive behavior in other parts of my life, so afterward I mostly just feel disgusted with myself and confused why I did it.

Can anyone relate?

Hello fellow meat lovers,

I’ve done this diet in the past and I usually only get a few days of flu like symptoms before my gut re-normalizes.

This time around, for some reason, it took 5 days for the flu symptoms to even show up (quite odd) and since then they’ve persisted for a week now.

On the bright side my energy is higher than past times I’ve transitioned to carnivore. In the past there’s been a definite drop in energy, this time it’s stayed pretty much consistent.

Any insight?

Thanks

Currently titrating up rather slowly. At 1mg now, shooting for 2.5.

Reports of it working well for anhedonia and depression. Seems like it should be a pretty good adjunct to the 75mg nardil (phenelzine) I’m also taking.

However, currently at 1mg pramipexole, and so far it’s not doing much for me. Actually seems to put me in a crabbier mood if I take it in the morning. Been at this dose 4 days now. I’ve heard it takes a while to work though. I’ve heard some success stories and also heard some people who gave up.

Any success stories in treating anhedonia / depression with it? Advice? Cautions?

Thank you 🙏

Currently titrating up rather slowly. At 1mg now, shooting for 2.5.

Reports of it working well for anhedonia and depression. Seems like it should be a pretty good adjunct to the 75mg nardil (phenelzine) I’m also taking.

However, currently at 1mg pramipexole, and so far it’s not doing much for me. Actually seems to put me in a crabbier mood if I take it in the morning. Been at this dose 4 days now. I’ve heard it takes a while to work though. I’ve heard some success stories and also heard some people who gave up.

Any success stories in treating anhedonia / depression with it? Advice? Cautions?

Thank you 🙏

Currently on 75mg nardil. little over 2 months now. Got prescribed ambien for the insomnia. I've taken ambien before and it's always put me to sleep, but on Nardil I didn't even notice a difference. I was still waking up every hour or two.

Additionally, if it kicks in while you're still awake, ambien is known to give you a sort of pleasurable "high." This dreamy, hypnotic state known for causing unusual behavior is responsible for ambien's infamy.

Well, that pleasurable state of mind never occured on Nardil. Could barely tell I'd taken it.

Then, to my great surprise and dissatifcation, I awoke the next day to find my depression had/has competely returned (and then some) and it was as if my Nardil pills had no effect at all. Unfortunately, by the time I read another nardil-user describe the same thing with ambien, I'd already dosed the ambien for the second night in a row. Following a single dose of ambien, this user described a serious relapse of depression/anxiety lasting a couple days.

Haven't been able to find the comment again.

Has anyone else experienced this? It's awful and I'm praying it is, in fact, the ambien. Can't find much more info on this specific combination of drugs.

Thanks

I'm back in the gym after some time off, and motivated to get as scientific as possible with training and recovery to maximize growth while minimizing overtraining/unhealthy stress on the nervous system, etc.

I once listened to a 2 hour recording of Mentzer explaining "rest-pause" and the method's results. I guess Dorian Yates basically used his method (although adapted it a bit) to get as big as he did. For both of them, it was very effective. The idea behind it makes sense, but it's so easy to overtrain apparently, and having to take off up to a week from a muscle group after what seems like not even that much training is tough and just seems like its gotta be a bit much. Hard to not want to get at least a couple more sets in, especially when you're lowkey addicted to lifting, like i am.

Here's a video explaining it:

[https://www.youtube.com/watch?v=\\\_Rls8F9PGnc&t=1s\](https://www.youtube.com/watch?v=\_Rls8F9PGnc&t=1s)

What do you guys think?

Some of y’all will probably think a zero carb diet like keto or carnivore isn’t healthy. That it’s a fad diet or associated with right wing nut jobs (and that might be true).

Preconceived notions aside. I’ve done it before and compared blood work. Also done my research. It’s not a fun diet but it’s healthy, and it’ll clear up a lot of health problems you’d be surprised about. Gets rid of bloating entirely (at least before nardil). Makes me look like a new man.

Anyone done this diet on an MAOI, specially nardil?

Nardil’s bloated me up like a balloon. It’s bad. Nobody will lend me their chapstick cause they think I’m gonna eat it now. The neighborhood kids beat me with sticks every time I try to step outside, calling me “La beastia.” This dude I squared up to the other day just pushed me and I rolled away, there was nothing I could do.

That last part might not be true, but keto/carnivore will make you drop water weight like nothing else. However, I’m curious how the metabolic changes on nardil affect the experience, if anyone has or is doing it.

Thanks

Something about the combination of sleep deprivation and this med (been on 2 months, at 75mg now) has destroyed the filter on what I say. It’s always been kind of bad, but it’s just gotten to the point where I’m finding everything funny and a couple times now I’ve made jokes which I think are funny but they’re kind of dumb, leaving me feeling embarrassed and not sure why I said that. It’s not like I can’t tell it’s an inappropriate context, in the moment I just dont care. It’s like my typical zaniness, along with every other “positive” aspect of my personality, has been amplified by the nardil and there’s been some “pixelation,” or loss of discernment, in the process of upscaling. Idk if that makes sense.

Anyone else experience this? Do I just need sleep?

Been on ‘bout 2 months, titrated up to 75mg.

Always had the most vivid dreams before. I’m talking about shit I could recall for hours (much to the displeasure of my captive audience.)

Now I literally have none. Closest thing is slightly more visual thoughts as I’m waking up, but really I think that’s just the result of thinking against the black background of my eyelids.

It’s unnerving. I don’t feel super deeply asleep either so I get up just like “what was doing the past 8 hours? Lying there?”

Does this go away? And to the extent it does, is that just the extent the nardil stops working as the body adjusts?

This Nardil sure is a game changer for depression and anxiety… but not dreaming feels pretty unhealthy. Dreams are a wild phenomenon and I’m a big believer that they aren’t just random. Feel like a mechanism by which my brain rejuvenates has got to be on pause or something.

I also wake up in the middle of the night stretching n shit which tells me my body isn’t really asleep.

Your thoughts?

Thanks

On 75mg now. Been on for about 1 month and 3 weeks. Started at 15mg, going up about 15mg every week (180lb male—did I titrate up too fast?)

Basically it’s all good. Like this stuff is really working in a way no other antidepressant has even come close to. My social anxiety is like GONE gone, and that was a big problem for me.

It’s to the point where all I want to do is go out and see friends. Being able to interact and socialize without being super self conscious or feeling like a timid little imp is super enticing. I always thought I was just a shy extrovert and that’s proving to be the case.

It’s to the point where I’m neglecting other things I seriously need to take care of. Job stuff. Health stuff. Suddenly life just seems super chill and the anxiety that causes me to objectively look at myself and take care of business is just gone.

I’m also having a tough time focusing. I always have, but it definitely almost feels like the nardil is making me less quick. My brain feels less willing to think along intellectual lines, which, not to toot my own horn here, but, that’s always been something I’m good at. I haven’t taken an iq test on nardil vs off, but it somehow feels like I’m not as smart. Sort of a separate issue though.

Did anyone experience something similar on nardil? And how to overcome? I’m taking .25mg pramipexole to combat sexual side effects, maybe I need to up the dose?

Overall it’s like a good problem to have, but if I continue like this my objective quality of life is gonna go to shit while I’m just frolicking in la la land, and I’d prefer if that wasn’t the case.

Thanks

Been taking 50mg hydroxyzine, 20mg melatonin, and now doxylamine succinate for sleep. Still barely sleeping and since taking the doxylamine last night felt so out of it today. (Too much antihistamines? I also take loratadine and Zyrtec during the day)

Someone recommended daridorexant for sleep on Nardil. Reading about it I’ve heard mixed things though. Bout to pick up my prescription tomorrow. What’s the verdict on this stuff?

Thanks

Really need input here

First post here. Let me know if I should be posting somewhere else.

Was going to post this in the physical therapy subreddit but I guess you're not allowed to solicit advice.

Been trying to fix a systemic asymmetry in my body for 10 years, learning about anatomy in the process.

It seems like every time I notice an asymmetry and work on it, it pops up elsewhere if that makes sense.

I'm aware there's patterns in the body that can become exacerbated from poor posture over time. I've seen many physical therapists to try and fix this. They don't do much for me I can't figure out on my own and seem to mostly just give me exercises that aren't super specific or targeted to what i'm dealing with.

Recently I've been working on fixing an anterior pelvic tilt and flat footedness. The left side is much more anteriorlly tilted, the left iliac crest being more flared out and down, and the outside of the left leg tighter, particularly in the medial glute and the muscles on the left side of the pelvis. The left side of my lumbar erectors are understandably tight. Additionally, of course, my left foot is much more flat and wants to flare out. I'm more knock-kneed on the left side, and it seems like i have a much more prminent valgus ankle deformity on that side. I can't lift my pinky toe on the left side without collapsing the arch. I'm working on that with stretching and strength training.

As I've been working to stretch the Rectus Femorus, the Tensor Fasciae Latae and Sartorius. Addiionally the lumbar erectors. This is helping but, perhaps unsurprisingly, exacerbating the assymetry, with an increase in tightness/increase in strength/compensation on the right side abdominals that extends down into the groin area. This would be a great sign if I was experiencing that on the left side too, but I really can't seem to find a way to target the left side of my abdominals unilaterally. Any exercise I do, my right side abdominals just wants to bear oll the weight, and I can't seem to focus to get them to stop. Right now, writing this, doing my best to relax them, the muscles around the lingual ligament on the right side are burning right now from being contracted, and yet those same muscles on the left side are flacid and uncontracted. The muscles on the inernal oblique/rectus abdominis on the right side are so much more pronounced, bulging out right above the pubis where the other side has no definition (don't care about the differency visually, but it demonstrates how much stronger something on this side is)

I think I need to somehow target that left side inner abdominals. I was hoping they'd "come online" along with the Gracilis, abductor magnus, abductor longus, abductor brevis, pectineus, and the other muscles in that area on the left side. In addition to the other asymetries described, i recently noticed while I'm walking, those muscles on the left side are just kind of loose and not firing. Or at least thats what it feels like.

How can I unilaterally fix this problem and influence that left side of my pelvis to rotate posteriorally? Any bilateral exercise or stretch i do seems to fail to correct this asymmetry and only make it worse.

Thanks

Really need input here

First post here. Let me know if I should be posting somewhere else.

Was going to post this in the physical therapy subreddit but I guess you're not allowed to solicit advice.

Been trying to fix a systemic asymmetry in my body for 10 years, learning about anatomy in the process.

It seems like every time I notice an asymmetry and work on it, it pops up elsewhere if that makes sense.

I'm aware there's patterns in the body that can become exacerbated from poor posture over time. I've seen many physical therapists to try and fix this. They don't do much for me I can't figure out on my own and seem to mostly just give me exercises that aren't super specific or targeted to what i'm dealing with.

Recently I've been working on fixing an anterior pelvic tilt and flat footedness. The left side is much more anteriorlly tilted, the left iliac crest being more flared out and down, and the outside of the left leg tighter, particularly in the medial glute and the muscles on the left side of the pelvis. The left side of my lumbar erectors are understandably tight. Additionally, of course, my left foot is much more flat and wants to flare out. I'm more knock-kneed on the left side, and it seems like i have a much more prminent valgus ankle deformity on that side. I can't lift my pinky toe on the left side without collapsing the arch. I'm working on that with stretching and strength training.

As I've been working to stretch the Rectus Femorus, the Tensor Fasciae Latae and Sartorius. Addiionally the lumbar erectors. This is helping but, perhaps unsurprisingly, exacerbating the assymetry, with an increase in tightness/increase in strength/compensation on the right side abdominals that extends down into the groin area. This would be a great sign if I was experiencing that on the left side too, but I really can't seem to find a way to target the left side of my abdominals unilaterally. Any exercise I do, my right side abdominals just wants to bear oll the weight, and I can't seem to focus to get them to stop. Right now, writing this, doing my best to relax them, the muscles around the lingual ligament on the right side are burning right now from being contracted, and yet those same muscles on the left side are flacid and uncontracted. The muscles on the inernal oblique/rectus abdominis on the right side are so much more pronounced, bulging out right above the pubis where the other side has no definition (don't care about the differency visually, but it demonstrates how much stronger something on this side is)

I think I need to somehow target that left side inner abdominals. I was hoping they'd "come online" along with the Gracilis, abductor magnus, abductor longus, abductor brevis, pectineus, and the other muscles in that area on the left side. In addition to the other asymetries described, i recently noticed while I'm walking, those muscles on the left side are just kind of loose and not firing. Or at least thats what it feels like.

How can I unilaterally fix this problem and influence that left side of my pelvis to rotate posteriorally? Any bilateral exercise or stretch i do seems to fail to correct this asymmetry and only make it worse.

Thanks

Hi there, I'm currently taking .25 mg promipexole in the morning alongside 60 mg Nardil (Phenelezine) a pretty potent MAOI antidepressant. I asked my doctor to prescribe the pramipexole to hopefully help ameliorate the Nardil side effects (pretty famous for sexual side effects) as well as to hopefully improve this incessant anhedonia I've had most my life.

Been taking the pramipexole about 3 weeks, the nardil about 6 weeks.

While I do seem to have some good effects from the pramipexole, it also seems to sap my energy and make me more anxious in the morning after taking it. I would take it at night but it seems to keep me up. I tried going up to .375 mg last week and felt kind of sick--out of it and heart rate at like 100bpm, although that could have been from something else.

I hear people talk about taking up to 4 mg pramipexole for anhedonia/depression, with some people claiming long term relief from anhedonia (and this kind of makes sense based on how the med supposedly works.)

I'm curious if anyone has dealt with this and potentially overcame it by increasing their dose to .5mg or more? I've heard up till a certain dosage point, pramipexole actually has the opposite of the positive dopaminergic effect people take it for, so it seems like something I might just have to power through if I want to get the positive effects.

I've been in a pretty low condition the past few years from this depression/anhedonia and the related avolition, and really let my life fall apart. Now I'm trying to rebuild it and just lacking the drive like I did as a kid.

Any input is welcome,

Thanks

Made a lot of posts on here recently cause I got a lot of questions so I appreciate everyone’s who’s given feedback/advice.

Feeling pretty woozy and out of it today. Haven’t slept well the past couple nights.

Taken my bp a couple times recently and it’s been like 140-150. Heart rate is like 100. Worked out kinda hard earlier today. Keep feeling on the edge of passing out.

Recently bumped the nardil dosage up to 60mg, been on it for a little over a month. Also taking .25mg pramipexole.

29 y/o male, theoretically healthy otherwise.

Anyone know what’s up. I feel off and I’m anxious about it.

Thanks