Venlafaxine significantly improved my autistic symptoms, confidence, and social anxiety, but I experienced severe withdrawal after stopping it. Should I consider taking it long-term?

Hi everyone. I'm 21 years old and have Asperger's syndrome (autism).

About a year ago, I took venlafaxine (37.5 mg) for five months. During that time, I experienced the biggest improvement in my confidence, social skills, mental sharpness, energy, and overall ability to function that I had ever experienced in my life.

I felt more confident, could express myself without losing my train of thought, and was much more socially comfortable. Almost all of my autism-related difficulties seemed to become significantly less noticeable.

Unfortunately, after five months, I stopped taking the medication abruptly, which led to severe withdrawal symptoms. I've now been off venlafaxine for about a year, and unfortunately, all the positive effects I experienced have disappeared.

Currently, I struggle with severe social anxiety. When I make eye contact with people on the street, my heart starts racing, I sweat, and I become extremely anxious. If someone suddenly calls my name or approaches me unexpectedly, I lose my composure and struggle to respond naturally. I've also lost the mental sharpness, confidence, and social flexibility I used to have. I often become indecisive and lose my train of thought while speaking.

I experienced something similar when I was 14. My doctor prescribed fluoxetine (60 mg), which I took for three years. I eventually stopped taking it because I had reached a weight of 95 kg. After discontinuing it, I developed even more severe symptoms than I currently have, including intense heart palpitations and such extreme anxiety that I could barely look outside my window at home.

Although my current condition isn't as severe as it was back then, I'm considering restarting venlafaxine under my doctor's guidance.

However, I'm concerned that if I start taking it again, I might need to remain on it for many years or possibly for the rest of my life. I don't know whether long-term antidepressant use is the right approach for me.

I'd really appreciate hearing from people who have had similar experiences, particularly those with autism and social anxiety.

- Have antidepressants like venlafaxine genuinely helped you with autistic-related social difficulties, confidence, and mental sharpness?

- If medication is effective, is long-term or even lifelong use sometimes necessary?

- Are there alternative treatments for autistic people with severe social anxiety that can be as effective as antidepressants?

- How much can a psychologist or autism-informed therapist help with these difficulties? Can therapy significantly improve social confidence, anxiety, and the ability to think clearly in social situations without medication?

- Has anyone experienced a similar loss of confidence, mental sharpness, and social functioning after discontinuing venlafaxine or fluoxetine?

I'm particularly interested in hearing about real-life experiences, including both medication and non-medication approaches.

Thank you for taking the time to read my post.

reddit.com
u/Normal-Surprise-533 — 12 days ago

How can I join my friend's TikTok LIVE as a guest from my PC and play MP3 audio?

Hello, I want to join music TikTok LIVE streams as a guest from my PC (not host my own LIVE). Is there any way to do that?

In the past, I joined as a guest using Android emulators, but TikTok has now restricted Android emulators. Is there any other way to join music LIVE streams as a guest from a PC?

reddit.com
u/Normal-Surprise-533 — 2 months ago
▲ 1 r/TikTok

How can I join my friend's TikTok LIVE as a guest from my PC and play MP3 audio?

Hello, I want to join music TikTok LIVE streams as a guest from my PC (not host my own LIVE). Is there any way to do that?

In the past, I joined as a guest using Android emulators, but TikTok has now restricted Android emulators. Is there any other way to join music LIVE streams as a guest from a PC?

reddit.com
u/Normal-Surprise-533 — 2 months ago

How can I join my friend's TikTok LIVE as a guest from my PC and play MP3 audio?

Hello, I want to join music TikTok LIVE streams as a guest from my PC (not host my own LIVE). Is there any way to do that?

In the past, I joined as a guest using Android emulators, but TikTok has now restricted Android emulators. Is there any other way to join music LIVE streams as a guest from a PC?

reddit.com
u/Normal-Surprise-533 — 2 months ago

Have any autistic adults significantly reduced anxiety with Vitamin D or Omega-3?

Hi everyone,

I'm 21 years old and I have mild Asperger syndrome (autism spectrum disorder). Since childhood, I've been treated for anxiety, OCD, and behavioral problems. Over the years I've taken several psychiatric medications, including risperidone, propranolol, venlafaxine, and fluoxetine. Currently, I'm only taking 5 mg of Abilify (aripiprazole).

I experience sudden anxiety attacks that usually begin with a heavy feeling around my eyes and a sense of distress. This is followed by irritability, emotional numbness, and an urge to imagine worst-case scenarios.

Unfortunately, I'm very sensitive to psychiatric medications. I've been taking psychotropic medications since I was very young, and I honestly feel exhausted by them. Because of both financial reasons and previous negative experiences, I don't feel comfortable starting psychotherapy right now.

Breathing exercises and grounding techniques help as temporary "first aid," but I have to use them 4–5 times every day. If I don't, my anxiety becomes so intense that I can barely think logically, and it's mentally exhausting.

My question is mainly for autistic adults:

Has anyone significantly reduced their anxiety with Vitamin D or Omega-3 supplements?

My current vitamin D level is 20 ng/mL. If you've had a similar experience, I'd really appreciate hearing whether Vitamin D, Omega-3, or any other nutritional supplement made a noticeable difference for your anxiety.

Thank you.

reddit.com
u/Normal-Surprise-533 — 2 months ago

Have any autistic adults significantly reduced anxiety with Vitamin D or Omega-3?

Hi everyone,

I'm 21 years old and I have mild Asperger syndrome (autism spectrum disorder). Since childhood, I've been treated for anxiety, OCD, and behavioral problems. Over the years I've taken several psychiatric medications, including risperidone, propranolol, venlafaxine, and fluoxetine. Currently, I'm only taking 5 mg of Abilify (aripiprazole).

I experience sudden anxiety attacks that usually begin with a heavy feeling around my eyes and a sense of distress. This is followed by irritability, emotional numbness, and an urge to imagine worst-case scenarios.

Unfortunately, I'm very sensitive to psychiatric medications. I've been taking psychotropic medications since I was very young, and I honestly feel exhausted by them. Because of both financial reasons and previous negative experiences, I don't feel comfortable starting psychotherapy right now.

Breathing exercises and grounding techniques help as temporary "first aid," but I have to use them 4–5 times every day. If I don't, my anxiety becomes so intense that I can barely think logically, and it's mentally exhausting.

My question is mainly for autistic adults:

Has anyone significantly reduced their anxiety with Vitamin D or Omega-3 supplements?

My current vitamin D level is 20 ng/mL. If you've had a similar experience, I'd really appreciate hearing whether Vitamin D, Omega-3, or any other nutritional supplement made a noticeable difference for your anxiety.

Thank you.

reddit.com
u/Normal-Surprise-533 — 2 months ago

Strange eye sensation that disappears with anxiety techniques – anyone else experienced this?

Hello,

I have mild Asperger syndrome, and I've been experiencing a strange symptom.

About a year ago, I stopped taking venlafaxine (37.5 mg) cold turkey. I had severe withdrawal symptoms, including brain zaps, OCD, and other issues. Most of those symptoms gradually improved, but one has never gone away.

Every day, I get a strange feeling in my eyes, almost like there's something inside them. When it happens, I can't think clearly or logically. I start feeling depressed and begin imagining negative scenarios in my head. It makes me feel really bad.

At first, I thought it was caused by lack of sleep because my eyelids feel heavy and want to close when this happens. However, I usually sleep 7–8 hours a night.

I also discovered that anti-anxiety techniques, such as face tapping, make the feeling disappear almost instantly. It works surprisingly well, but I have to do it regularly. If I don't, I can't think clearly again. The problem is that I can't always do these techniques in public.

Has anyone experienced something similar? Could this be related to autism, anxiety, or venlafaxine withdrawal?

reddit.com
u/Normal-Surprise-533 — 2 months ago

Strange eye sensation that disappears with anxiety techniques – anyone else experienced this?

Hello,

I have mild Asperger syndrome, and I've been experiencing a strange symptom.

About a year ago, I stopped taking venlafaxine (37.5 mg) cold turkey. I had severe withdrawal symptoms, including brain zaps, OCD, and other issues. Most of those symptoms gradually improved, but one has never gone away.

Every day, I get a strange feeling in my eyes, almost like there's something inside them. When it happens, I can't think clearly or logically. I start feeling depressed and begin imagining negative scenarios in my head. It makes me feel really bad.

At first, I thought it was caused by lack of sleep because my eyelids feel heavy and want to close when this happens. However, I usually sleep 7–8 hours a night.

I also discovered that anti-anxiety techniques, such as face tapping, make the feeling disappear almost instantly. It works surprisingly well, but I have to do it regularly. If I don't, I can't think clearly again. The problem is that I can't always do these techniques in public.

Has anyone experienced something similar? Could this be related to autism, anxiety, or venlafaxine withdrawal?

reddit.com
u/Normal-Surprise-533 — 2 months ago

Venlafaxine completely changed my autistic symptoms and confidence. Is it worth trying again?

Hi everyone,

I'm 21 years old and I have Asperger's syndrome (autism spectrum disorder).

I've struggled with low self-confidence and anxiety since childhood. When I was 18, my psychiatrist prescribed venlafaxine 37.5 mg. I took it for about 5 months, and it was honestly the best I had ever felt in my life. My anxiety was dramatically reduced, I became much more confident, and I could express myself much more naturally in conversations.

Unfortunately, I had to stop venlafaxine abruptly because it caused severe throat problems. After stopping it, I experienced intense withdrawal symptoms, including insomnia, severe anxiety, brain zaps, and other withdrawal effects.

At the moment, I'm only taking aripiprazole 5 mg, which I've been on since I was 8 years old.

I've learned to manage my anxiety reasonably well through mindfulness and breathing exercises. However, one problem that existed before I started venlafaxine has returned. When someone gives me instructions or tells me something, I often misunderstand what they mean. My mind starts considering many different possible interpretations, and I struggle to decide which one is actually correct. It feels like my brain gets "stuck" analyzing possibilities instead of reaching a clear conclusion.

As far as I understand, this type of thinking is related to autism itself, so I wouldn't expect an antidepressant to eliminate autistic traits. That's what confuses me—while I was taking venlafaxine, almost all of these problems seemed to disappear.

I'm seriously considering trying venlafaxine again, but I've also heard that antidepressants can become less effective after years or after restarting them.

Has anyone experienced something similar? If you've restarted venlafaxine after stopping it, was it as effective the second time? Do you think it's reasonable to discuss restarting it with my psychiatrist, or are there other options I should ask about?

I'd really appreciate hearing about both personal experiences and any evidence-based information.

reddit.com
u/Normal-Surprise-533 — 3 months ago

Venlafaxine completely changed my autistic symptoms and confidence. Is it worth trying again?

Hi everyone,

I'm 21 years old and I have Asperger's syndrome (autism spectrum disorder).

I've struggled with low self-confidence and anxiety since childhood. When I was 18, my psychiatrist prescribed venlafaxine 37.5 mg. I took it for about 5 months, and it was honestly the best I had ever felt in my life. My anxiety was dramatically reduced, I became much more confident, and I could express myself much more naturally in conversations.

Unfortunately, I had to stop venlafaxine abruptly because it caused severe throat problems. After stopping it, I experienced intense withdrawal symptoms, including insomnia, severe anxiety, brain zaps, and other withdrawal effects.

At the moment, I'm only taking aripiprazole 5 mg, which I've been on since I was 8 years old.

I've learned to manage my anxiety reasonably well through mindfulness and breathing exercises. However, one problem that existed before I started venlafaxine has returned. When someone gives me instructions or tells me something, I often misunderstand what they mean. My mind starts considering many different possible interpretations, and I struggle to decide which one is actually correct. It feels like my brain gets "stuck" analyzing possibilities instead of reaching a clear conclusion.

As far as I understand, this type of thinking is related to autism itself, so I wouldn't expect an antidepressant to eliminate autistic traits. That's what confuses me—while I was taking venlafaxine, almost all of these problems seemed to disappear.

I'm seriously considering trying venlafaxine again, but I've also heard that antidepressants can become less effective after years or after restarting them.

Has anyone experienced something similar? If you've restarted venlafaxine after stopping it, was it as effective the second time? Do you think it's reasonable to discuss restarting it with my psychiatrist, or are there other options I should ask about?

I'd really appreciate hearing about both personal experiences and any evidence-based information.Venlafaxine completely changed my autistic symptoms and confidence. Is it worth trying again?

reddit.com
u/Normal-Surprise-533 — 3 months ago
▲ 3 r/autism

Venlafaxine completely changed my autistic symptoms and confidence. Is it worth trying again?

Hi everyone,

I'm 21 years old and I have Asperger's syndrome (autism spectrum disorder).

I've struggled with low self-confidence and anxiety since childhood. When I was 18, my psychiatrist prescribed venlafaxine 37.5 mg. I took it for about 5 months, and it was honestly the best I had ever felt in my life. My anxiety was dramatically reduced, I became much more confident, and I could express myself much more naturally in conversations.

Unfortunately, I had to stop venlafaxine abruptly because it caused severe throat problems. After stopping it, I experienced intense withdrawal symptoms, including insomnia, severe anxiety, brain zaps, and other withdrawal effects.

At the moment, I'm only taking aripiprazole 5 mg, which I've been on since I was 8 years old.

I've learned to manage my anxiety reasonably well through mindfulness and breathing exercises. However, one problem that existed before I started venlafaxine has returned. When someone gives me instructions or tells me something, I often misunderstand what they mean. My mind starts considering many different possible interpretations, and I struggle to decide which one is actually correct. It feels like my brain gets "stuck" analyzing possibilities instead of reaching a clear conclusion.

As far as I understand, this type of thinking is related to autism itself, so I wouldn't expect an antidepressant to eliminate autistic traits. That's what confuses me—while I was taking venlafaxine, almost all of these problems seemed to disappear.

I'm seriously considering trying venlafaxine again, but I've also heard that antidepressants can become less effective after years or after restarting them.

Has anyone experienced something similar? If you've restarted venlafaxine after stopping it, was it as effective the second time? Do you think it's reasonable to discuss restarting it with my psychiatrist, or are there other options I should ask about?

I'd really appreciate hearing about both personal experiences and any evidence-based information.

reddit.com
u/Normal-Surprise-533 — 3 months ago

Venlafaxine completely changed my autistic symptoms and confidence. Is it worth trying again?

Hi everyone,

I'm 21 years old and I have Asperger's syndrome (autism spectrum disorder).

I've struggled with low self-confidence and anxiety since childhood. When I was 18, my psychiatrist prescribed venlafaxine 37.5 mg. I took it for about 5 months, and it was honestly the best I had ever felt in my life. My anxiety was dramatically reduced, I became much more confident, and I could express myself much more naturally in conversations.

Unfortunately, I had to stop venlafaxine abruptly because it caused severe throat problems. After stopping it, I experienced intense withdrawal symptoms, including insomnia, severe anxiety, brain zaps, and other withdrawal effects.

At the moment, I'm only taking aripiprazole 5 mg, which I've been on since I was 8 years old.

I've learned to manage my anxiety reasonably well through mindfulness and breathing exercises. However, one problem that existed before I started venlafaxine has returned. When someone gives me instructions or tells me something, I often misunderstand what they mean. My mind starts considering many different possible interpretations, and I struggle to decide which one is actually correct. It feels like my brain gets "stuck" analyzing possibilities instead of reaching a clear conclusion.

As far as I understand, this type of thinking is related to autism itself, so I wouldn't expect an antidepressant to eliminate autistic traits. That's what confuses me—while I was taking venlafaxine, almost all of these problems seemed to disappear.

I'm seriously considering trying venlafaxine again, but I've also heard that antidepressants can become less effective after years or after restarting them.

Has anyone experienced something similar? If you've restarted venlafaxine after stopping it, was it as effective the second time? Do you think it's reasonable to discuss restarting it with my psychiatrist, or are there other options I should ask about?

I'd really appreciate hearing about both personal experiences and any evidence-based information.

reddit.com
u/Normal-Surprise-533 — 3 months ago
▲ 2 r/NoFap

Is porn triggering my insomnia and mood issues?

Hello, I'm on the autism spectrum (Asperger's). I jerk off maybe 4-5 times a week, sometimes daily. I don't think I'm addicted to porn or anything, but I watch it sometimes. The thing is—after I watch it, I get really insomnia and irritable for like 2-3 days afterward. Could the porn be what's triggering this?

reddit.com
u/Normal-Surprise-533 — 3 months ago

Has anyone become much more emotional after stopping venlafaxine? I feel stuck in an endless cycle

Hi everyone,

I'm 21 years old and I have Asperger syndrome. About a year ago, I stopped taking venlafaxine (Effexor/Velaxin). Ever since then, I've become much more emotional, indecisive, and easily irritated, even over small things.

When I'm physically or mentally exhausted, my mind starts creating terrible scenarios. I become afraid of losing my parents, afraid of "going crazy" or ending up in a psychiatric hospital. Even though I have no desire to act on them, I get intrusive suicidal thoughts and my mind creates suicide scenarios that I don't want. During those moments, I often listen to sad music, which only makes me feel even worse.

Sometimes I can keep these feelings inside, but other times I become very emotional at home. I start pacing around the house and complaining or venting to my mom because I feel overwhelmed.

I feel like I'm trapped in an endless cycle, and I don't know how to break out of it.

Has anyone else experienced something similar after stopping venlafaxine or dealt with intrusive thoughts like these? What helped you recover or cope with it?

Please, if you've been through something similar, I'd really appreciate your advice or experiences. Thank you.

reddit.com
u/Normal-Surprise-533 — 4 months ago

Has anyone become much more emotional after stopping venlafaxine? I feel stuck in an endless cycle

Hi everyone,

I'm 21 years old and I have Asperger syndrome. About a year ago, I stopped taking venlafaxine (Effexor/Velaxin). Ever since then, I've become much more emotional, indecisive, and easily irritated, even over small things.

When I'm physically or mentally exhausted, my mind starts creating terrible scenarios. I become afraid of losing my parents, afraid of "going crazy" or ending up in a psychiatric hospital. Even though I have no desire to act on them, I get intrusive suicidal thoughts and my mind creates suicide scenarios that I don't want. During those moments, I often listen to sad music, which only makes me feel even worse.

Sometimes I can keep these feelings inside, but other times I become very emotional at home. I start pacing around the house and complaining or venting to my mom because I feel overwhelmed.

I feel like I'm trapped in an endless cycle, and I don't know how to break out of it.

Has anyone else experienced something similar after stopping venlafaxine or dealt with intrusive thoughts like these? What helped you recover or cope with it?

Please, if you've been through something similar, I'd really appreciate your advice or experiences. Thank you.

reddit.com
u/Normal-Surprise-533 — 4 months ago

Has anyone become much more emotional after stopping venlafaxine? I feel stuck in an endless cycle

Hi everyone,

I'm 21 years old and I have Asperger syndrome. About a year ago, I stopped taking venlafaxine (Effexor/Velaxin). Ever since then, I've become much more emotional, indecisive, and easily irritated, even over small things.

When I'm physically or mentally exhausted, my mind starts creating terrible scenarios. I become afraid of losing my parents, afraid of "going crazy" or ending up in a psychiatric hospital. Even though I have no desire to act on them, I get intrusive suicidal thoughts and my mind creates suicide scenarios that I don't want. During those moments, I often listen to sad music, which only makes me feel even worse.

Sometimes I can keep these feelings inside, but other times I become very emotional at home. I start pacing around the house and complaining or venting to my mom because I feel overwhelmed.

I feel like I'm trapped in an endless cycle, and I don't know how to break out of it.

Has anyone else experienced something similar after stopping venlafaxine or dealt with intrusive thoughts like these? What helped you recover or cope with it?

Please, if you've been through something similar, I'd really appreciate your advice or experiences. Thank you.

reddit.com
u/Normal-Surprise-533 — 4 months ago

Abizol 5 mg istifadə edən var?

Salam mənim 21 yaşım var yüngül Asperger sendromuyam 8 yaşımda video oyunu travması nəticəsində çox pis qorxular yaşamışam və o vaxtdan indiyə qədər Abizol qəbul edirəm.Əvvələr məndə əlavə olaraq okp,ağır davranış pozuntusu,bahalı şeylər aldırma istəyi olurdu.Hal hazırda əvvəlkinə nisbətən çox yaxşıyam özgüvənsizlik, anksiyeteni çıxsaq(: mən keçmişdə çox dərmanlar qəbul etmişəm antidepressantlar,beta bloker və.s amma ən uzun qəbul etdiyim dərman bu olub.Sualım odurki bu dərmanı qəbul edən Autistik şəxslərdə halsizliq, yorğunluq, enerjisizlik,hipersekuallığa oxşar simptomlar olub?

reddit.com
u/Normal-Surprise-533 — 4 months ago

Hansı psixoloqa müraciət edəcəyimi bilmirəm

Salam mənim 21 yaşım var yüngül Asperger sendromuyam uzaqdan normal biri kimi görünürəm amma içdə problemlərim var.Özgüvən problemi,diqqət dağınıqlığı ,Anksiyete,qərarsızlıq,Tez tez bir şey səhf başa düşmə(Autistik xüsusiyyət) və.s 8 yaşımdan qorxularıma görə antipsixotik qəbul edirəm əlavə dərman istəmədiyim üçün psxiatra getmək istəmirəm.Bu problemlərimi həll etmək üçün güvənilir psixoloq lazımdır.

reddit.com
u/Normal-Surprise-533 — 4 months ago

Long-term aripiprazole use, autism, anxiety, and severe fatigue – has anyone experienced something similar?

Hi everyone,

​

I'm a 20-year-old male diagnosed with Asperger's syndrome (autism spectrum disorder). Since childhood, I've struggled with OCD, severe fears, anxiety, insomnia, and behavioral problems.

​

I've been under psychiatric treatment since I was 8 years old and have taken different medications over the years, including antidepressants, beta blockers, and antipsychotics.

​

I started taking aripiprazole (Abilify) at age 8 after developing intense fears following a traumatic experience related to a video game. I'm still taking it today.

​

At age 12, my father was concerned about weight gain and asked my psychiatrist if I could stop aripiprazole. I was taking 5 mg at the time. My doctor suggested reducing it to 2.5 mg for one week and then stopping completely.

​

After discontinuing it, my condition became much worse. I completely lost control of my behavior, became extremely distressed, and my family had to take me urgently to my psychiatrist. I restarted aripiprazole immediately, and later my dose was increased to 7.5 mg.

​

During childhood and adolescence, I had severe behavioral problems. I often demanded expensive things, threatened my parents, isolated myself from others, and struggled so much that my education was significantly affected. I hurt my parents emotionally many times, even though I didn't feel fully in control of my behavior.

​

These problems gradually improved and became much less severe around age 17.

​

At 17, I stopped taking fluoxetine after using it for about three years. After that, I developed severe anxiety. Even looking outside my house made my heart race. My doctor prescribed propranolol (40 mg), which I took for about a year.

​

During that time, I slowly started improving my social skills and interacting more with people.

​

Later, because my psychiatrist felt I had improved significantly compared to childhood, they again suggested stopping aripiprazole. My mother was uncomfortable with this idea, so instead my dose was reduced from 7.5 mg to 5 mg, and propranolol was discontinued.

​

After that, I developed insomnia, especially sudden awakenings just as I was falling asleep.

​

Another psychiatrist prescribed venlafaxine (37.5 mg) and Mebicar (300 mg). Mebicar was stopped after 1–2 weeks, but I continued venlafaxine for five months.

​

During those five months, I felt better than I had in years. My anxiety decreased, my confidence improved, and I was finally comfortable talking to people.

​

Unfortunately, I had to stop venlafaxine because it caused throat problems. After stopping it, I experienced severe withdrawal symptoms for 4–5 months.

​

Since then, I've been dealing with:

​

- Difficulty falling asleep

- Sudden awakenings while falling asleep

- Heavy, tired eyes

- Extreme fatigue and low energy

- Inability to nap during the day even when exhausted

- Increased irritability and anxiety

​

Magnesium glycinate helped somewhat, but after a severe flu, my sleep problems returned.

​

Earlier this year, my psychiatrist prescribed quetiapine (12.5 mg) at night. I took it for 22 days alongside aripiprazole.

​

At first, my sleep improved, but then I developed intense compulsive urges to masturbate and still couldn't sleep during the day despite feeling exhausted.

​

I stopped quetiapine and later discovered I had a vitamin D deficiency. Taking vitamin D improved my energy and concentration somewhat, but my symptoms returned after finishing the course.

​

Recently, I tried quetiapine again: aripiprazole 5 mg in the morning and quetiapine 12.5 mg at night.

​

For about 20 days, I felt much better. But now I've developed new problems:

​

- Feeling extremely groggy in the mornings

- Severe fatigue that improves later in the day

- Emotional numbness and emptiness

- Crying spells

- Feeling hopeless and overwhelmed

​

At this point, I feel exhausted and lost.

​

Has anyone with autism, OCD, anxiety, or long-term aripiprazole use experienced something similar?

​

Could these symptoms be related to aripiprazole, quetiapine, withdrawal from previous medications, or something else?

​

What helped you recover?

​

Thank you for reading.

reddit.com
u/Normal-Surprise-533 — 4 months ago

Long-term aripiprazole use, autism, anxiety, and severe fatigue – has anyone experienced something similar?

Hi everyone,

​

I'm a 20-year-old male diagnosed with Asperger's syndrome (autism spectrum disorder). Since childhood, I've struggled with OCD, severe fears, anxiety, insomnia, and behavioral problems.

​

I've been under psychiatric treatment since I was 8 years old and have taken different medications over the years, including antidepressants, beta blockers, and antipsychotics.

​

I started taking aripiprazole (Abilify) at age 8 after developing intense fears following a traumatic experience related to a video game. I'm still taking it today.

​

At age 12, my father was concerned about weight gain and asked my psychiatrist if I could stop aripiprazole. I was taking 5 mg at the time. My doctor suggested reducing it to 2.5 mg for one week and then stopping completely.

​

After discontinuing it, my condition became much worse. I completely lost control of my behavior, became extremely distressed, and my family had to take me urgently to my psychiatrist. I restarted aripiprazole immediately, and later my dose was increased to 7.5 mg.

​

During childhood and adolescence, I had severe behavioral problems. I often demanded expensive things, threatened my parents, isolated myself from others, and struggled so much that my education was significantly affected. I hurt my parents emotionally many times, even though I didn't feel fully in control of my behavior.

​

These problems gradually improved and became much less severe around age 17.

​

At 17, I stopped taking fluoxetine after using it for about three years. After that, I developed severe anxiety. Even looking outside my house made my heart race. My doctor prescribed propranolol (40 mg), which I took for about a year.

​

During that time, I slowly started improving my social skills and interacting more with people.

​

Later, because my psychiatrist felt I had improved significantly compared to childhood, they again suggested stopping aripiprazole. My mother was uncomfortable with this idea, so instead my dose was reduced from 7.5 mg to 5 mg, and propranolol was discontinued.

​

After that, I developed insomnia, especially sudden awakenings just as I was falling asleep.

​

Another psychiatrist prescribed venlafaxine (37.5 mg) and Mebicar (300 mg). Mebicar was stopped after 1–2 weeks, but I continued venlafaxine for five months.

​

During those five months, I felt better than I had in years. My anxiety decreased, my confidence improved, and I was finally comfortable talking to people.

​

Unfortunately, I had to stop venlafaxine because it caused throat problems. After stopping it, I experienced severe withdrawal symptoms for 4–5 months.

​

Since then, I've been dealing with:

​

- Difficulty falling asleep

- Sudden awakenings while falling asleep

- Heavy, tired eyes

- Extreme fatigue and low energy

- Inability to nap during the day even when exhausted

- Increased irritability and anxiety

​

Magnesium glycinate helped somewhat, but after a severe flu, my sleep problems returned.

​

Earlier this year, my psychiatrist prescribed quetiapine (12.5 mg) at night. I took it for 22 days alongside aripiprazole.

​

At first, my sleep improved, but then I developed intense compulsive urges to masturbate and still couldn't sleep during the day despite feeling exhausted.

​

I stopped quetiapine and later discovered I had a vitamin D deficiency. Taking vitamin D improved my energy and concentration somewhat, but my symptoms returned after finishing the course.

​

Recently, I tried quetiapine again: aripiprazole 5 mg in the morning and quetiapine 12.5 mg at night.

​

For about 20 days, I felt much better. But now I've developed new problems:

​

- Feeling extremely groggy in the mornings

- Severe fatigue that improves later in the day

- Emotional numbness and emptiness

- Crying spells

- Feeling hopeless and overwhelmed

​

At this point, I feel exhausted and lost.

​

Has anyone with autism, OCD, anxiety, or long-term aripiprazole use experienced something similar?

​

Could these symptoms be related to aripiprazole, quetiapine, withdrawal from previous medications, or something else?

​

What helped you recover?

​

Thank you for reading.

reddit.com
u/Normal-Surprise-533 — 4 months ago