u/alexmillne

For People Who Drank Heavily Before GLP-1 Medications: What Exactly Changed for You?

For those of you who used to drink a lot before starting a GLP-1 medication like Mounjaro, Zepbound, Ozempic, Wegovy, etc. — and now either stopped drinking or reduced it heavily — what exactly changed inside you?

Was it that alcohol no longer gave you the same buzz or euphoric feeling, so you simply lost interest in it?
Did the craving disappear?
Did drinking start feeling flat, pointless, or even unpleasant?
Or was it more that the obsessive “pull” toward alcohol quieted down mentally?

I’m really curious about the actual switch that happened for you psychologically and physically.

What is now stopping you from drinking the way you used to while on these medications?

reddit.com
u/alexmillne — 4 days ago

For People Who Drank Heavily Before GLP-1 Medications: What Exactly Changed for You?

For those of you who used to drink a lot before starting a GLP-1 medication like Mounjaro, Zepbound, Ozempic, Wegovy, etc. — and now either stopped drinking or reduced it heavily — what exactly changed inside you?

Was it that alcohol no longer gave you the same buzz or euphoric feeling, so you simply lost interest in it?
Did the craving disappear?
Did drinking start feeling flat, pointless, or even unpleasant?
Or was it more that the obsessive “pull” toward alcohol quieted down mentally?

I’m really curious about the actual switch that happened for you psychologically and physically.

What is now stopping you from drinking the way you used to while on these medications?

reddit.com
u/alexmillne — 4 days ago

For people who used to drink heavily before starting a GLP-1 medication and have now stopped or massively reduced drinking: what exactly changed for you?

I’m really curious about the mechanism behind it.

Was it that alcohol simply stopped giving you that euphoric buzz, so your brain no longer found it rewarding? Did the craving disappear? Did you start feeling sick more easily? Did the urge to “keep going” just vanish? Or was it more emotional/mental than physical?

I recently drank while on a GLP-1 and noticed something strange: I could tell I was intoxicated, but the usual rewarding buzz/euphoria just wasn’t really there. It almost felt flat. But because I wasn’t getting the feeling I expected, I found myself chasing it and drinking more than I intended.

So I’m trying to understand: for those of you who now barely drink or stopped completely, what was the actual “switch” for you? What is now stopping you from drinking?

reddit.com
u/alexmillne — 4 days ago

Alcohol Feels “Flat” on Mounjaro… But I Still Kept Drinking

I’m currently on 2.5mg Mounjaro and had my first real night out drinking since starting it.

What surprised me most was that alcohol felt completely different. The usual buzz, euphoria, and rewarding feeling just weren’t really there. At the start of the night I was drinking incredibly slowly, almost like I had a natural resistance or lack of desire to drink more.

Normally after a couple of drinks I start wanting stronger alcohol and chasing that fun, outgoing feeling. But this time I mostly just felt… flat towards it. Like my brain wasn’t getting the same reward from alcohol anymore.

The strange part is that it still didn’t stop me from drinking.

I think because the buzz felt muted, part of me kept trying to “find” it by continuing to drink. And once the alcohol itself lowered my inhibitions later in the night, I eventually lost control anyway and drank far more than I originally intended.

What did feel different though was that the night didn’t spiral into other impulsive behaviours the way it normally can for me. And the next-day shame spiral felt dramatically reduced too, which honestly felt huge.

So now I’m really curious about other people’s experiences:

  • Did moving up from 2.5mg make the alcohol aversion much stronger?
  • Did alcohol eventually stop feeling worth it because the buzz stayed muted?
  • Or is this actually the ideal moment to consciously quit drinking altogether while the compulsive “pull” is quieter?

Would really appreciate hearing from people who’ve experienced something similar.

reddit.com
u/alexmillne — 4 days ago

Mounjaro Took Away the Buzz… But Not the Drinking. Did Increasing the Dose Change That for You?

I’m currently on 2.5mg Mounjaro and had my first real night out drinking on it last weekend.

What shocked me was that alcohol felt… different. The buzz and euphoria felt much more muted, and I was drinking way slower at the beginning of the night. It almost felt like the “reward” from alcohol wasn’t fully there anymore.

But despite that, it didn’t actually stop me from drinking. In a way, I almost kept chasing the feeling I normally get from alcohol because it felt so blunted. I still ended up drinking a lot by the end of the night, especially once the alcohol itself lowered my inhibitions.

What did feel different though was that the night didn’t spiral into other impulsive behaviours the way it normally can for me, and the next-day shame spiral felt much less intense too.

So now I’m wondering:

  • Did anyone notice a much stronger alcohol aversion once increasing from 2.5mg to higher doses?
  • Did the “muted buzz” eventually make alcohol feel not worth it anymore?
  • Or is this actually the perfect window/opportunity to consciously quit altogether while the compulsive drive is quieter?

Would genuinely love to hear experiences from people who used this medication to change their relationship with alcohol too.

reddit.com
u/alexmillne — 4 days ago

Mounjaro Made Alcohol Feel “Flat”... But I Still Drank. Has Anyone Else Experienced This?

I’m currently on 2.5mg Mounjaro and had my first real night out drinking on it last weekend.

What shocked me was that alcohol felt… different. The buzz and euphoria felt much more muted, and I was drinking way slower at the beginning of the night. It almost felt like the “reward” from alcohol wasn’t fully there anymore.

But despite that, it didn’t actually stop me from drinking. In a way, I almost kept chasing the feeling I normally get from alcohol because it felt so blunted. I still ended up drinking a lot by the end of the night, especially once the alcohol itself lowered my inhibitions.

What did feel different though was that the night didn’t spiral into other impulsive behaviours the way it normally can for me, and the next-day shame spiral felt much less intense too.

So now I’m wondering:

  • Did anyone notice a much stronger alcohol aversion once increasing from 2.5mg to higher doses?
  • Did the “muted buzz” eventually make alcohol feel not worth it anymore?
  • Or is this actually the perfect window/opportunity to consciously quit altogether while the compulsive drive is quieter?

Would genuinely love to hear experiences from people who used this medication to change their relationship with alcohol too.

reddit.com
u/alexmillne — 4 days ago

For people who used to drink heavily before starting GLP-1 medication: what exactly changed for you?

I’m really curious about the psychological side of this.

Did alcohol simply stop giving you that euphoric buzz or rewarding feeling, so you naturally lost interest in drinking? Or was it something deeper than that?

What was the actual “switch” for you after starting the medication?

Was it:

  • less craving?
  • less obsession/thoughts about alcohol?
  • feeling full or sick more quickly?
  • alcohol feeling emotionally flat or unrewarding?
  • reduced impulsivity?
  • less desire to escape or “let loose”?
  • stronger self-control around other people drinking?

I’d really love to understand what specifically changed in your mind and body that made you stop drinking or cut down so much.

reddit.com
u/alexmillne — 4 days ago

Meine erste Erfahrung mit Alkohol auf Mounjaro: Als plötzlich der ganze Belohnungs-Loop nicht mehr funktionierte

Meine erste Erfahrung mit Alkohol auf Mounjaro (2.5mg) war psychologisch extrem faszinierend.

  • Das war mein ALLERERSTES Mal trinken auf dem Medikament, deshalb wusste ich überhaupt nicht, was mich erwartet.
  • Ich bin einfach wie immer an den Abend rangegangen: gleiche Denkweise, gleiches Tempo, gleiche automatisierte Verhaltensmuster.
  • Rückblickend glaube ich genau das war das Problem: Mein Körper und Gehirn reagierten komplett anders, aber psychologisch lief immer noch mein alter Loop.
  • Das Seltsamste: selbst nach ungefähr 6 Drinks bekam ich nie wirklich den Buzz, den ich eigentlich gesucht habe.
  • Normalerweise macht Alkohol mich euphorisch, sozial, laut, stimuliert, emotional aufgedreht. Dieses typische: „Die Nacht lebt.“
  • Auf Mounjaro war dieser ganze Reward-Loop plötzlich stark gedämpft.
  • Psychologisch fühlte es sich fast so an, als würde ich alkoholfreie Drinks trinken.
  • Ich wartete die ganze Zeit auf den emotionalen Payoff… aber er kam nie richtig.
  • Genau das kann wahrscheinlich gefährlich werden: man trinkt weiter, weil das Gehirn denkt: „Der Effekt kommt sicher gleich noch.“
  • Und dann passierte etwas seltsames: der Alkohol traf mich körperlich erst Stunden später.
  • Aber selbst dann war es nicht dieser euphorische Dopamin-High, den ich normalerweise chase.
  • Mein Körper war betrunken. Mein Gehirn fühlte sich aber kaum belohnt.
  • Diese Trennung hat mich komplett überrascht: BODY drunk, BRAIN nicht belohnt.
  • Ich glaube genau das könnte ein Teil davon sein, warum GLP-1s manchen Menschen beim Alkohol helfen: sie erzeugen enttäuschende Reward-Erfahrungen.
  • Das Gehirn lernt plötzlich: „Ich trinke viel, bekomme kaum den gewünschten Effekt und habe TROTZDEM die negativen Konsequenzen.“
  • In meinem Fall: schlechter Schlaf, Hangover, Dehydration, körperliche Erschöpfung… aber ohne den emotionalen Reward, der das Verhalten normalerweise verstärkt.
  • Und psychologisch verändert das die Erwartungsschleife für zukünftige Abende.
  • Denn jetzt denkt mein Gehirn: „Will ich das überhaupt noch, wenn ich sowieso kaum einen Buzz bekomme?“
  • Gleichzeitig war das alte psychologische Skript trotzdem noch da: „Mach weiter.“ „Lass die Nacht nicht enden.“ „Vielleicht bringt der nächste Drink endlich das Gefühl.“
  • Genau dort wurde mir klar: GLP-1 reduziert vielleicht den biologischen Reward, aber nicht automatisch jahrelange emotionale Konditionierungen und Gewohnheiten.
  • Ein weiterer riesiger Unterschied: normalerweise spirale ich nach solchen Nächten komplett ab: Hangxiety → Scham → compulsive behavior → Doomscrolling → Porn → Vermeidung → Selbsthass.
  • Dieses Mal war diese Spirale massiv leiser.
  • Es fühlte sich an, als wäre zum ersten Mal SPACE zwischen Impuls und Reaktion entstanden.
  • Und ich glaube genau das könnte die eigentliche Stärke dieser Medikamente sein: nicht Magie, sondern genug Ruhe im Reward-System, um die eigenen Loops endlich klar sehen zu können.
  • Die größte Lektion für mich: wenn Alkohol plötzlich weniger rewarding wird, dann gegen dieses Signal anzukämpfen und einfach weiter zu trinken, verstärkt wahrscheinlich genau den Loop, aus dem man eigentlich raus möchte.
  • Ich bin ehrlich gesagt noch unsicher, wie ich in Zukunft damit umgehen will.
  • Ein Teil von mir denkt: „Wenn der Buzz sowieso weg ist… was ist dann überhaupt noch der Sinn vom Trinken?“
  • Denn selbst nach mehreren Drinks fühlte ich mich später eigentlich nur körperlich betrunken, aber ohne diesen emotionalen Dopamin-Kick.
  • Ein anderer Teil von mir denkt: vielleicht einfach sozial 1-2 Drinks trinken und danach auf alkoholfrei wechseln.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago

How GLP-1s Exposed My Dopamine & Addiction Loops

My first experience drinking on Mounjaro (2.5mg) taught me something psychologically fascinating about addiction loops, reward systems, and learned behavior:

  • This was my VERY FIRST time drinking alcohol on the medication, so I genuinely didn’t know what to expect. I basically approached the night the same way I always used to: same mindset, same pacing, same automatic behavioral script.
  • Looking back now, I think that was the mistake. My brain and body were reacting completely differently, but psychologically I was still following the old loop out of habit.
  • The strangest part: even after around 6 drinks, I never got the feeling I was actually looking for. No buzz that I so badly desired...
  • Normally alcohol gives me a strong dopamine response: I become hyped up, extra social, emotionally excited, loud, stimulated, “the night is alive.”
  • On Mounjaro, that entire reward loop felt muted.
  • It felt like I was drinking non-alcoholic drinks psychologically. I kept waiting for the emotional payoff to arrive, but it never really came.
  • The really dangerous part is that this can trick you into continuing to drink MORE because your brain keeps expecting the old reward to eventually kick in.
  • And then something weird happened: the alcohol only really “hit” me physically hours later.
  • But even then, it wasn’t the classic euphoric buzz I normally chase. It was mostly just my body being physically drunk: slower coordination, physical intoxication
  • Mentally though? The dopamine high still wasn’t there.
  • That distinction completely blew my mind: my BODY was drunk, but my BRAIN never really got rewarded.
  • I think this may actually be part of why GLP-1s can help some people reduce drinking over time: they create disappointing reward experiences.
  • The brain starts learning: “Wait… I drank a lot, didn’t really get the buzz I wanted, and STILL got the negative consequences.”
  • In my case: delayed intoxication, poor sleep, physical hangover, dehydration, exhaustion… without the emotional payoff that normally reinforced the behavior.
  • And psychologically, that changes the anticipation loop for future nights out.
  • Because now my brain is questioning: “Do I even want to drink next time if I already know I may need 5-6 drinks just to feel something physically… and even then the mental reward still isn’t really there?”
  • That feels very different from traditional dieting or “willpower.” It feels more like the reward-learning system itself is being disrupted.
  • Psychologically, the learned script was still there: “keep going” “don’t let the night end” “maybe the next drink will finally create the feeling.”
  • That’s when I understood: GLP-1s may reduce the biological reward, but they don’t automatically erase years of emotional conditioning and behavioral habits.
  • Another huge thing: normally after a night like that, I spiral the next day: hangxiety → shame → compulsive behaviors → doom scrolling → porn → avoidance → self-hatred.
  • This time the shame loop was dramatically quieter.
  • It felt like there was finally SPACE between urge and reaction.
  • And I think that space may be the real therapeutic power of these medications: not magic, not instant self-control, but enough quieting of the reward system to finally SEE the loops clearly while they’re happening.
  • Biggest lesson for me: if alcohol suddenly feels less rewarding, fighting through that signal and continuing to drink harder is probably reinforcing the exact compulsive cycle I’m trying to escape.
  • I’m still unsure how I want to move forward after this experience.
  • Part of me thinks: “If the buzz is basically gone, what’s the point of drinking at all?”
  • Even after multiple drinks, I mostly just felt physically drunk later on, but without the dopamine reward or emotional excitement I normally chase.
  • Another part of me thinks maybe I should just socially have 1-2 drinks, then switch to non-alcoholic ones.
reddit.com
u/alexmillne — 4 days ago
▲ 10 r/UKMounjaro+4 crossposts

My First Weekend on Mounjaro: Hope, Alcohol, Dopamine, and the Reality of Addiction

I took my first shot of Mounjaro, 2.5mg, on Tuesday evening, and I was blown away by how quickly I felt a change in myself. The constant chatter in my head quietened down. The food noise disappeared. The porn spirals, the endless YouTube doom scrolling, all of it suddenly lost its grip on me. I felt clear-headed, calm, focused. It genuinely felt like something had shifted in my dopamine reward system, and that made me incredibly excited, especially because one of my biggest struggles is alcohol and not knowing when to stop once I start drinking.

Saturday was Eurovision night here in Europe, so a big night out. I was nervous about how my body would react to alcohol on Mounjaro, but at the same time I was really hoping this medication would help with my drinking patterns too.

I started the evening at my friend’s house where we had wine. Straight away I noticed something was different. I couldn’t drink quickly. I don’t even fully know how to explain it. It almost felt like an aversion, or at least a lack of desire. I was sipping incredibly slowly, enough that my friend even noticed. I had two glasses of wine, and then we went to the nightclub.

Normally by that point I’d already be quite drunk, but this time I felt strangely sober, definitely not feeling that usual buzz or rush I normally chase. And instead of ordering strong liquor like I usually would, I ordered a beer. That alone was already very unlike me.

Over the course of many hours I had around six drinks in total, and even then I still felt oddly “flat” towards the alcohol. Like the rewarding part of it just wasn’t really there. I longed and missed my outgoing alcoholic behaviour.. something felt “off”.

But then around 3 a.m. things changed. I started letting loose, ordered stronger drinks like gin and tonics, and the night escalated from there. In total I ended up having around 13 drinks all night and stayed out until the early morning hours.

I did have fun. I genuinely had an amazing night. But at the same time, the pattern was still the same: everything after 3 a.m. was not worth it. That’s always the part I regret. The part where the night stops being meaningful and just becomes compulsive excess. And that’s exactly why I was so excited about this medication in the first place.

What I do find interesting though is that Mounjaro still seemed to blunt the escalation. Even after the night spiraled, it only stayed with alcohol. Normally a night like that could spiral into other impulsive or self-destructive behaviours too, but it didn’t. It felt like the medication put some kind of ceiling on things. And honestly, I suspect that without that blunting effect, it could have escalated much further, like consuming other things.

Something else that really stood out to me happened the next morning. When I woke up, I immediately felt dread. That horrible “oh my God, what did I do, how do I feel?” feeling. Usually that immediately throws me into a shame spiral where I numb myself with porn, doom scrolling, and more compulsive behaviour. But this time I didn’t. I really didn’t. And I genuinely think that’s because of the Mounjaro. It felt like it interrupted the usual shame-addiction cycle enough for me to recover emotionally much quicker.

So I feel both encouraged and disappointed at the same time. Encouraged because the medication clearly helped in multiple ways. But disappointed because I had secretly hoped for an even stronger effect on the drinking itself.

I also realise part of this was me exploring and testing the waters. I wanted to see what this medication actually feels like in real life situations. And one thing I noticed is that because the rewarding “buzz” from alcohol felt muted, there’s a danger there too. Does that eventually help me stop because drinking no longer feels worth it? Or does my brain start chasing the missing feeling by drinking more and faster to force it?

That’s the part I’m still unsure about.

I’m also only on 2.5mg, which is a very low starting dose, even though I’m already reacting strongly to it in other areas like eating and compulsive behaviours. So part of me wonders whether the alcohol aversion would become much stronger at a higher dose.

What I found fascinating though was how real the aversion felt at the beginning of the night, the slow drinking, the lack of desire, and then how quickly it faded once my brain became disinhibited from alcohol itself. It was almost like the alcohol overrode the medication once I crossed a certain point.

But even then, something still held. I didn’t take anything else. It stayed just alcohol. And for me, that’s actually very significant.

What this experience really showed me is that Mounjaro is not magic. It helps enormously, but I can already tell I need therapy alongside it. The medication may quieten the compulsive drive, but I still need to work on the emotional patterns, the binge mentality, the “keep going” switch that flips in me after a certain hour of the night.

 

u/alexmillne — 5 days ago

DoktorABC - Schweiz,.. wow so einfach?

Hi Leute

Ich hab gerade meine erste Bestellung über DoktorABC gemacht. Ganz normales Rezept für 5mg Mounjaro. Ehrlich gesagt bin ich etwas schockiert, wie unkompliziert das ging 😅

Jetzt überlege ich, dort auch direkt 7.5mg zu bestellen. Läuft das dann genau gleich einfach ab? Irgendwie fühlt es sich fast zu einfach an und ich frage mich, ob das in Zukunft vielleicht mal strenger wird oder gar nicht mehr erlaubt ist.

Und was mich auch interessiert: Wenn man mit Mounjaro schon länger erfolgreich Gewicht verliert, meint ihr, dass einem dann grundsätzlich auch ein normaler Arzt in der Schweiz das Medikament weiter verschreiben würde?

Danke euch schon mal 🙏

reddit.com
u/alexmillne — 7 days ago

Fragen an Langzeitnutzer von Tirzepatid/Mounjaro: Food Noise, Essanfälle, Alkohol, zwanghaftes Verhalten & Erhaltungstherapie

Hallo zusammen

Ich habe vor Kurzem mit Mounjaro/Tirzepatid 2.5 mg angefangen und würde mich freuen, von Leuten zu hören, die schon länger damit Erfahrung haben.

Ich bin 171 cm gross, wiege 85 kg und habe einen BMI von etwa 29, also knapp unter der üblichen Grenze von BMI 30. Mein Hauptgrund war natürlich Gewichtsverlust, weil ich über Jahre wirklich vieles ausprobiert habe und das Gewicht immer wieder zurückkam.

Was mich aber ehrlich gesagt am meisten interessiert hat, war die Wirkung auf süchtige bzw. zwanghafte Verhaltensmuster. Ich kämpfe mit Food Noise, gelegentlichem Binge Eating, Binge Drinking, nächtlichen YouTube-Spiralen, Pornokonsum, Impulsivität und diesem ständigen „nur noch einmal“-Gefühl. Oft fühlt es sich an, als würde mein Gehirn permanent nach Dopamin und neuen Reizen suchen, obwohl ich weiss, dass es mir langfristig nicht guttut.

Ich bin erst seit einer Woche auf 2.5 mg, aber ich bin ehrlich gesagt ziemlich überrascht. Die Wirkung auf meine Impulsivität ist enorm. Ich spüre deutlich weniger diesen Sog zu stundenlangem Scrollen, Pornos, Alkohol oder anderen Belohnungs-/Dopaminmustern. Es ist fast so, als hätte jemand die Lautstärke in meinem Kopf heruntergedreht. Ich habe plötzlich mehr Raum für normale Dinge im Alltag, wie aufräumen, Freunde treffen oder bewusst entscheiden, was ich tun möchte, statt einfach von Impulsen mitgezogen zu werden.

Ich weiss, das klingt vielleicht dramatisch, aber bisher fühlt es sich nach viel mehr an als nur „weniger Appetit“.

Ich suche keine medizinischen Ratschläge, sondern echte Erfahrungsberichte.

Meine wichtigsten Fragen:

  • Hatte jemand schon auf 2.5 mg so starke Effekte? Haben sie angehalten oder nachgelassen?
  • Wie lange hat 2.5 mg bei euch funktioniert, bevor ihr erhöhen musstet?
  • Ist jemand langfristig auf 2.5 mg geblieben, auch für Maintenance?
  • Falls ihr mit BMI 29–30 gestartet seid: Wie war eure Gewichtsabnahme?
  • Hat es bei euch Food Noise, Binge Eating, Alkoholverlangen oder andere zwanghafte Verhaltensmuster reduziert?
  • Hat jemand Veränderungen bei Dingen wie Scrollen, Pornos, Shopping, Glücksspiel, Alkohol oder anderen Dopamin-/Belohnungsverhalten bemerkt?
  • Hat dieses ruhigere, weniger belohnungsgetriebene Gefühl langfristig angehalten?
  • An Leute, die seit 1–2 Jahren dabei sind: Wurden die Effekte mit der Zeit schwächer?
  • Hat jemand erfolgreich die Strategie „niedrigste wirksame Dosis“ verfolgt?
  • Wie habt ihr die Maintenance gehandhabt? Gleiche Dosis, reduziert, Spritzenabstand verlängert oder komplett gestoppt?
  • Falls ihr pausiert und später wieder angefangen habt: Hat es gleich gut funktioniert?
  • Wie habt ihr Protein, Kalorien, Krafttraining und Muskelerhalt gemanagt, wenn der Appetit sehr niedrig war?
  • Rückblickend: Was würdet ihr in den ersten Monaten anders machen?
  • Hat euch das Medikament geholfen, langfristig Gewohnheiten zu verändern, oder hat es eher nur die Impulse unterdrückt?
  • Bei Themen wie Binge Eating, Alkohol, Pornos, Scrollen oder generell zwanghaftem Belohnungsverhalten: Hat es sich eher wie ein „Heilmittel“, ein Werkzeug oder irgendetwas dazwischen angefühlt?

Ich würde mich besonders über Antworten von Leuten freuen, die:

  • seit mindestens einem Jahr auf einem GLP-1 sind,
  • Gewicht erfolgreich halten,
  • mit BMI 29–30 gestartet sind,
  • oder deutliche Veränderungen bei Food Noise, Alkohol, Binge Eating, Pornos, Scrollen oder anderen zwanghaften Verhaltensmustern bemerkt haben.

Vielen Dank :)

u/alexmillne — 7 days ago

Long-Term Mounjaro/Tirzepatide Users: Has It Helped Your Food Noise, Addictive Behaviours & Weight Long-Term?

Hi everyone

I recently started Mounjaro/tirzepatide 2.5 mg and would love to hear from people who have been on it longer.

I’m 85 kg, 171 cm, BMI around 29, so just under the usual BMI 30 threshold. My main reason for starting was weight loss, because I’ve tried so many things over the years and always regained the weight.

But honestly, what really caught my attention was the addictive/compulsive side. I struggle with food noise, occasional binge eating, binge drinking, late-night YouTube spirals, porn, impulsivity, and that constant “just one more” feeling. It often feels like my brain is chasing dopamine and novelty, even when I know it’s not good for me.

I’ve only been on 2.5 mg for one week, but I’m honestly shocked. The effect on my impulsivity has been massive. I don’t feel that same pull toward all-night binges, scrolling, porn, drinking, or reward-chasing. It’s like the volume has been turned down in my brain. I suddenly have more space to do normal life things, like cleaning, seeing friends, and actually choosing what I want to do instead of being dragged by urges.

I know this sounds dramatic, but so far it feels like it’s helping with much more than appetite.

I’m not looking for medical advice, just real-world experiences.

My main questions:

  1. Did anyone feel strong effects already on 2.5 mg, and did they last or fade?
  2. How long did 2.5 mg work for you before increasing?
  3. Did anyone stay on 2.5 mg long-term for weight loss or maintenance?
  4. If you started around BMI 29–30, what was your weight-loss experience?
  5. Did it reduce food noise, binge eating, alcohol cravings, or compulsive behaviors beyond food?
  6. Did anyone notice reduced urges around scrolling, porn, shopping, gambling, drinking, or other dopamine-seeking behaviors?
  7. Did the calmer, less reward-driven feeling continue long-term?
  8. For people on it 1–2 years, did the effects weaken over time?
  9. Has anyone used a “lowest effective dose” strategy successfully?
  10. For maintenance, did you stay on the same dose, lower it, space injections out, or stop?
  11. If you stopped and restarted, did it work the same again?
  12. How did you manage protein, calories, weight training, and muscle preservation when appetite was low?
  13. Looking back, what do you wish you had done differently in the first few months?
  14. Did it help you actually change habits long-term, or mainly suppress urges while on it?
  15. For addictive-type patterns like binge eating, binge drinking, scrolling, porn, or compulsive reward-seeking, did it feel like a cure, a tool, or something in between?

I’d especially appreciate answers from people who have been on a GLP1 (monjaro or whatever) for a year or longer, people maintaining weight loss, people who started around BMI 29–30, or people who noticed changes in food noise, alcohol, binge eating, porn, scrolling, or other compulsive behaviors.

Thanks so much.

u/alexmillne — 7 days ago

Long-Term Tirzepatide/Mounjaro Users: Questions About Food Noise, Addictive Behaviours & Maintenance

Hi everyone

I recently started Mounjaro/tirzepatide 2.5 mg and would love to hear from people who have been on it longer.

I’m 85 kg, 171 cm, BMI around 29, so just under the usual BMI 30 threshold. My main reason for starting was weight loss, because I’ve tried so many things over the years and always regained the weight.

But honestly, what really caught my attention was the addictive/compulsive side. I struggle with food noise, occasional binge eating, binge drinking, late-night YouTube spirals, porn, impulsivity, and that constant “just one more” feeling. It often feels like my brain is chasing dopamine and novelty, even when I know it’s not good for me.

I’ve only been on 2.5 mg for one week, but I’m honestly shocked. The effect on my impulsivity has been massive. I don’t feel that same pull toward all-night binges, scrolling, porn, drinking, or reward-chasing. It’s like the volume has been turned down in my brain. I suddenly have more space to do normal life things, like cleaning, seeing friends, and actually choosing what I want to do instead of being dragged by urges.

I know this sounds dramatic, but so far it feels like it’s helping with much more than appetite.

I’m not looking for medical advice, just real-world experiences.

My main questions:

  1. Did anyone feel strong effects already on 2.5 mg, and did they last or fade?
  2. How long did 2.5 mg work for you before increasing?
  3. Did anyone stay on 2.5 mg long-term for weight loss or maintenance?
  4. If you started around BMI 29–30, what was your weight-loss experience?
  5. Did it reduce food noise, binge eating, alcohol cravings, or compulsive behaviors beyond food?
  6. Did anyone notice reduced urges around scrolling, porn, shopping, gambling, drinking, or other dopamine-seeking behaviors?
  7. Did the calmer, less reward-driven feeling continue long-term?
  8. For people on it 1–2 years, did the effects weaken over time?
  9. Has anyone used a “lowest effective dose” strategy successfully?
  10. For maintenance, did you stay on the same dose, lower it, space injections out, or stop?
  11. If you stopped and restarted, did it work the same again?
  12. How did you manage protein, calories, weight training, and muscle preservation when appetite was low?
  13. Looking back, what do you wish you had done differently in the first few months?
  14. Did it help you actually change habits long-term, or mainly suppress urges while on it?
  15. For addictive-type patterns like binge eating, binge drinking, scrolling, porn, or compulsive reward-seeking, did it feel like a cure, a tool, or something in between?

I’d especially appreciate answers from people who have been on a GLP1 (monjaro or whatever) for a year or longer, people maintaining weight loss, people who started around BMI 29–30, or people who noticed changes in food noise, alcohol, binge eating, porn, scrolling, or other compulsive behaviors.

Thanks so much.

u/alexmillne — 7 days ago

Food noise, binge eating, alcohol, compulsivity, and maintenance

Hi everyone

I recently started Mounjaro/tirzepatide 2.5 mg and would love to hear from people who have been on it longer.

I’m 85 kg, 171 cm, BMI around 29, so just under the usual BMI 30 threshold. My main reason for starting was weight loss, because I’ve tried so many things over the years and always regained the weight.

But honestly, what really caught my attention was the addictive/compulsive side. I struggle with food noise, occasional binge eating, binge drinking, late-night YouTube spirals, porn, impulsivity, and that constant “just one more” feeling. It often feels like my brain is chasing dopamine and novelty, even when I know it’s not good for me.

I’ve only been on 2.5 mg for one week, but I’m honestly shocked. The effect on my impulsivity has been massive. I don’t feel that same pull toward all-night binges, scrolling, porn, drinking, or reward-chasing. It’s like the volume has been turned down in my brain. I suddenly have more space to do normal life things, like cleaning, seeing friends, and actually choosing what I want to do instead of being dragged by urges.

I know this sounds dramatic, but so far it feels like it’s helping with much more than appetite.

I’m not looking for medical advice, just real-world experiences.

My main questions:

  1. Did anyone feel strong effects already on 2.5 mg, and did they last or fade?
  2. How long did 2.5 mg work for you before increasing?
  3. Did anyone stay on 2.5 mg long-term for weight loss or maintenance?
  4. If you started around BMI 29–30, what was your weight-loss experience?
  5. Did it reduce food noise, binge eating, alcohol cravings, or compulsive behaviors beyond food?
  6. Did anyone notice reduced urges around scrolling, porn, shopping, gambling, drinking, or other dopamine-seeking behaviors?
  7. Did the calmer, less reward-driven feeling continue long-term?
  8. For people on it 1–2 years, did the effects weaken over time?
  9. Has anyone used a “lowest effective dose” strategy successfully?
  10. For maintenance, did you stay on the same dose, lower it, space injections out, or stop?
  11. If you stopped and restarted, did it work the same again?
  12. How did you manage protein, calories, weight training, and muscle preservation when appetite was low?
  13. Looking back, what do you wish you had done differently in the first few months?
  14. Did it help you actually change habits long-term, or mainly suppress urges while on it?
  15. For addictive-type patterns like binge eating, binge drinking, scrolling, porn, or compulsive reward-seeking, did it feel like a cure, a tool, or something in between?

I’d especially appreciate answers from people who have been on a GLP1 (monjaro or whatever) for a year or longer, people maintaining weight loss, people who started around BMI 29–30, or people who noticed changes in food noise, alcohol, binge eating, porn, scrolling, or other compulsive behaviors.

Thanks so much.

u/alexmillne — 7 days ago