I will never touch Mounjaro again after horrific abdominal pain and diarrhoea
I have been on Mounjaro since March 2025 with a starting BMI of 30.1. My current BMI is 25.1. I am short and don’t carry the excess weight well and I was having some other health issues and my doctor recommended losing some weight. Initially I had lost more than 15kg but had noticed the weight starting to creep back on so on Sunday 9th August I decided to give myself a 2.5mg dose. I had the usual feeling of fullness/indigestion type feeling for the first two days post. On the morning of the 10th I had an episode of diarrhoea. I wasn’t too concerned until later in the morning I had to turn around from a lunch date with friends and become friends with my toilet. I also had significant abdominal cramping pain. I continued to have profuse diarrhoea and severe abdominal pain for the next two days. Eating even crackers was rewarded with intense diarrhoea and pain. I wasn’t keeping up with fluid intake. On the 15th I presented to hospital and was admitted post CT with proctocolitis. Intravenous fluids and pain relief were most welcome.
I continued on clear fluids for the next two days and then was allowed to try a light diet. I again had severe abdominal pain and diarrhoea which only stopped when all the ‘offensive’ food had been evacuated. The pain was again intense and I was forced to resort to strong pain medication. I had one of the most miserable nights of my life.
My bloods remained normal - no raised inflammatory markers. My stool specimens have come back normal. My temperature was normal. No signs of infection.
Today the 19th of August I still have a slight constant stomach ache. However I have managed to eat a light diet at lunch and dinner with no return of symptoms. All being well I will be discharged tomorrow morning after 5 nights in hospital. I will still need to be on a light diet until the niggly pain in my stomach goes away.
Was it Mounjaro that caused this week of misery? I know my doctor was very puzzled with how I was presenting and was surprised my first trial of a light diet was such an abysmal failure. I just know I’m never going to have another dose of Mounjaro to test it out. I will say perhaps I don’t have the full picture yet as I still need to have an endoscopy/colonoscopy in a couple of weeks to rule out other causes.