r/PMS

▲ 1 r/PMS+1 crossposts

IR (HOMA 6.63) 🔴 without diabetes - 500mg Metformin NOT working after 7 days, safe to increase? 🧐

Dear community,

I'm 32 years old.

A week ago I was diagnosed with insulin resistance (no diabetes/pre-diabetes). My lab results:

  • Glucose: 5.2
  • HbA1c: 5.32
  • Fasting Insulin: 28.70 ⬆️
  • HOMA-IR: 6.63 ⬆️

Despite being in a calorie deficit, 🍟 ⛔ drinking 1.5–2L water daily, 🌊 and exercising regularly for years, I keep gaining weight continuously (need to lose ~30kg). 😡

My endocrinologist prescribed Metformin (Glucophage) 500mg and advised staying on it for 3 MONTHS. ❓

I've been taking it for 7 days alongside daily moderate exercise and controlled intake, but I see no changes on the scale. 😔

P.S. Strict Keto is not an option for me due to intense carbohydrate cravings (especially during PMS), so please refrain from recommending full Keto. 🥦

Questions:

  1. Is 500mg METFORMIN ER 💊 just a starter dose, or should I give it more time than 7 days to start seeing weight loss?
  2. Is it safe to gradually increase to 1,000mg or 1,500mg XR on my own, or should I definitely seek a second opinion first? 😕
  3. I experience severe PMS symptoms 🩸 (facial/thigh swelling, palpitations, blood pressure surges but, WITHOUT high pressure or cholesterol). Could these be directly linked to high insulin? ❓
  4. I DON'T HAVE PCOS!

Would really appreciate any advice or personal experiences! 💗

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u/AlternativeMuscle582 — 8 days ago
▲ 4 r/PMS+1 crossposts

Do you remember your first period?

This week I finished Sterling Point, and got totally obsessed about Maple's first period scene and how it was for Annie without having a sister and mother to be there for her. 😭

If you could go back and talk to yourself on the day you got your first period, what would you say?

No medical advice. Just something you wish someone had told you.

u/figaro2402 — 7 days ago
▲ 4 r/PMS+1 crossposts

How do you deal with an aversion to food/nausea when you’re 3-5 days away from your period?

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u/kathnap — 8 days ago