r/Ureaplasma

Hi, I am positive UP while pregnant and symptomatic - burning urination, incr discharge that is ammonia smelling, urgency. SO nervous for this to affect the pregnancy. I am only 10 weeks. I have tried initially 1000 mg of azithromycin prescribed by an urgent care, then another dr said 1000 for 1 day followed by 500 a day for 4 days, still didn’t work. My OBGYN now has me on erythromycin 4x/day for a week.

Has anyone successfully treated UP without doxy or mino ???? With PREGNANCY SAFE meds? I’ve read through the Bible post and can’t seem to find my answer there. SOS. Thank you!

Just wanted to give some hope! After 14 days doxy and 1g azithromycin, I have testing negative and lingering symptoms have subsided! It took about 4 weeks to feel normal again (no urgency or frequency to pee) post treatment. I focused on stress management and went to pelvic floor physio which both really helped.

Got ureaplasma last November, got antibiotics for it and thought it was gone. Went to gyno last Thursday for a different issue and she tested for it again and it was positive. But im confused on how I keep getting it. I got married last October, so me and my partner have been active since then as we are trying to get pregnant. But I asked him if he's got any symptoms of it himself and he said he doesn't. Hes been my only partner since ive met him 3 years ago. How do I keep getting it but not him? Previous partners ive never had any symptoms for it. I also tend to get utis more often than a normal person.

I got a call from my gyno that I tested positive for ureaplasma. I'm 23 and went in for my first papsmear and questions about how to get rid of some Molluscum Contageosum on my butt.

I said I thought I might have a yeast infection from the harsh adapalene I was using on the MC, so he took a swab for additional testing.

It turns out I have ureaplasma, not a yeast infection. I've never even heard of ureaplasma before, what is it, how could I have gotten it, was I born with it? Maybe it's Maybelline?!?!

Jokes aside, I've done some quick scanning on this sub, and some medical descriptions/symptoms. I guess I'm on here looking for what other people's experiences are with this, what you're symptoms are like, how you found out you have it, and how you got it. I don't know much about this and I'm a little scared.

I've only ever had 4 sexual partners. For partners One and Two I was both of their first, and I know that as a 100% fact.

Partner Three was a very limited sexual relationship, we only had sex 4 times, used condoms every single time, and no oral. Partner Four is my current boyfriend, I love him very much, but I am nervous to talk with him about this because idk much about it and how it might affect his health or if I might have gotten it from him. He said he was clear of all STD and STI. He had testing with his last partner because they almost had an oops baby when a condom slipped off, but she miscarried 2 or so months in.

I know ureaplasma isn't something that is usually tested for, especially in men, but I'm wondering if I got it from him or if I've had it and been asymptomatic. I swear I've never even had a yeast infection until I started having sex with him, but a few months into our relationship, I started getting super itchy sometimes, uti symptoms, and random yeast infections. I thought they were all unrelated, I thought I was irritated down there from a new laundry soap or toothpaste lingering on his mustache. I thought the UTI was from not drinking enough water.

But I'm guessing all those new issues were ureaplasma.

I've been to the Dr's before for undiagnosed chronic illness, suspected POTS. I've struggled with my immune system flaring up, random feverish symptoms, hives, swelling joints, swollen lymphnodes my whole life but I've never had problems with my lady bits besides painful crazy heavy periods.

I'm really trying to figure out if I've had it all this time or if it's a recent thing, or if that even matters.

I'd like any and all information you have, any advice, especially how to talk about it to my partner. Thank you for listening to my freaked out talkings!

Exactly as the title says!

I am on my last day of doxycycline and am about to start taking azithromycin tomorrow. I’ve been using Life Space’s Women’s Microflora Probiotic as well as the Herbs of Gold + SB probiotics (specifically for saccharomyces boulardii) throughout treatment as recommended by some of you guys on here! Of course, I have been consuming them all the appropriate amount of hours apart.

However, how long should I continue taking these probiotics after treatment? I am very happy to continue them without any end in sight since it seems like they’ve been helping me immensely. Thanks!

Hi all

I’m in Australia, if that’s relevant.

Tested positive to Ureaplasma Urealyticum about 18 months ago, because of BV symptoms. Was given Metronidazole gel (the first line BV treatment) but it obviously didn’t work because it is likely being caused by the UU.

So I’m going to go to my GP this week - she’s super knowledgeable with women’s health, and will agree to whatever tests I ask for.

Since the last test was 18 months ago I’m going to ask for another PCR swab test, just to see if maybe mycoplasma has joined the party too, but other than ureaplasma and mycoplasma, is there anything else I should get her to add to the test form?

Thanks all :)

I just finished my course of doxycycline (14 days 100mgs 2x daily)
I feel as if some symptoms have exacerbated since finishing the doxycycline. I noticed probiotics make it worse too.

I’m having irritation, slight burning when wearing underwear (I don’t wear any at night), and general discomfort in my urethra. Low back pain and pelvic pain as well.

Is this normal after stopping the antibiotics? Is there anything I can take or do to help manage symptoms? It’s very uncomfortable

I tested positive for UP while I was pregnant and read every horror story on the internet… preterm birth, stillborns, miscarriages. They stuck with me my entire pregnancy and riddled me with fear. The doctors didn’t really seem to worry even though I treated it three times throughout pregnancy… to no avail.

Turns out, all the worrying and stress wasn’t worth any of it. Everything turned out perfect. I got induced at 39+3 and my baby girl is here. I just wanted to share this because I was hoping to see post like this while I was pregnant.

Hi, I've (21FTM) been lurking on this sub for awhile and now looking for experiences from others who have dealt with Ureaplasma parvum and lingering symptoms after treatment.

Starting in late 2024 I dealt with recurrent UTIs (approximately 5-6 over several months), recurrent yeast infections, and BV twice. I had about 5 months of no infections starting last November, until I seemingly got a UTI. I had lingering symptoms after 5 days of Macrobid that eventually calmed down, but I was not back to normal. Maybe two weeks later, I had a huge flare that didn't go away. After a bunch of doctor's appointments with urology and gynecology, I was eventually diagnosed with Ureaplasma parvum via vaginal swab in March 2026. I was previously tested via urine sample which was negative, but I think there's a chance that the urine sample didn't detect it at that time. I completed a 10 day course of doxycycline (100mg twice daily) about a month ago and my partner was treated simultaneously (he was asymptomatic; treated with 7 days of doxy). I also started pelvic floor therapy in March of this year, mainly due to other reasons (PTSD causing pelvic floor tension), but also because of the recurrent infections.

Prior to the Ureaplasma diagnosis I was also treated for vaginal inflammation with a topical steroid, and had multiple antibiotic courses for UTIs (generally Macrobid or Cipro). Unfortunately, my old doctors never really did urine cultures (minus a few times, once showing Klebsiella aerogenes; also have had UTIs in the past for E. coli) and only went off urinalysis. My theory is that I likely had ureaplasma all along (most likely from a previous partner, which is when this all started). I've dealt with UTIs throughout my childhood, but never anything like this. My first yeast infection (and BV) was right after sleeping with my ex for the first time, and everything seemed to spiral from there. I've been with the same partner now for over a year (March 2025), and I think I probably passed the ureaplasma along to him.

Improvements since treatment:

- Urinary symptoms significantly better overall

- Tolerating previous bladder irritants (coffee, alcohol) without much issue

- Discharge improving; shifted from watery back toward more normal cream/yellow texture. It's still much thinner than my normal (with some "chunks" for lack of a better term of thicker, stringier discharge that is probably the closest to normal for me), but it's not the watery discharge that I was dealing with prior to treatment.

Lingering symptoms I'm still dealing with:

- Mild persistent post-void urethral sensation (warm, almost like a drop is there after urinating)

- Most noticeable after first morning void and when dehydrated

- Generally improves throughout the day with hydration

- Discharge still not fully back to my normal baseline (fluctuating and slightly less than normal)

Overall I'd describe it as extremely mild but persistently present.

My questions:

How long after completing doxycycline did your urethral symptoms fully resolve?

Did symptoms fluctuate during recovery (better some days, worse others)?

Did discharge take a long time to fully normalize?

I know that doxy + azithro is commonly recommended in this sub, but I 100% trust my gyno's opinion as she has never led me wrong during all of this. The 10 days of doxy does seem to have worked, and while I still have mild symptoms, it's a night and day difference. Antibiotic use has caused other health problems for me, so I felt like just doing the doxy was the best course of action at that point (my gyno also agreed). As for a test of cure, I will likely be tested in early July at my urogyno consult. My gyno is over 2 hours away from me, so getting retested isn't very straightforward and not currently even an option for me.

Also to add that my partner and I entirely abstained during this time (we didn't even seen each other for awhile due to unrelated life circumstances). We only had sex for the first time again two weeks ago, and I'd been done with doxy for a few weeks (he had finished a week and a half prior). I know many recommend abstaining until a negative test result, but I strictly followed the guidance of my gyno and trust her judgment. We took every possible precaution, and I did not flare at all afterwards (just still the mild symptoms that I was already dealing with).

I'm aware of all the recommendations regarding treatment, TOC, and sex, but right now I'm just looking for people's experiences with the recovery timeline, not any of those things.

Thank you!!

I (19F) just tested positive for ureaplasma after experiencing symptoms for the past ~3 weeks (no pain). I was sent a prescription for doxycycline. What I'm wondering is how the hell I got it!! I've only had one sexual partner in the past 2+ years and I haven't done it unprotected for over a year. I dont think my boyfriend cheated on me or anything (me and my entire family has his location and we live together). How did this happen?? I don't want him to think I cheated on him either (I didn't, obviously.)

Hey everyone, just got my urine PCR back positive for ureaplasma parvum at low microbial load.

My urologist wants to put me on a fluoroquinolone but given everything I’ve read in CPPS I’m hesitant.

Has anyone tested positive for ureaplasma parvum specifically at low load and chosen not to take antibiotics?

Did symptoms resolve naturally through PT, supplements, or lifestyle changes alone?

Would really appreciate hearing from anyone who went the non-antibiotic route and what happened.

i am positive for ureaplasma parvum. what exactly are/were your symptoms? how persistent they are?

mine are basically just constant burning of urethrra opening- sometimes milder, other times bad flare ups. no other. there is often no pain relief for this kind of pain for me.

my story:
i am 20. even before sexual activity, i have been having sometimes burning flares up of unbearable stinging. no cause found. once i hat antibiotics for uti. i was confirmed for ureaplasma this year in march, after having my first sexual encounter this year. i have been dealing with pain daily since the first sex, 5 months now. it is basically just the burning, no other symptoms at all (bad discharge and stomach pain occurred just on antibiotics). i am not fifth antibiotics, doesnt seem to get better. i have been to more specialists, everyone only says antibiotics should work, others said maybe the cause is something else. i am negative for other std. there was one reinfection possibility after the third antibiotics. the pain makes me miserable. i feel ignored by specialists.

Hi I'm not sure if men have this toovor I'm a rare case and all posts I read are from women or maybe men are in different sub reddit I don't know of.
But I do need your help.
I've had this since last November I guess. I had a fling with a girl and I'm sure she gave it to me. I always use protection and she said she doesn't like condom so we did it raw Everytime it felt good but now I'm regretting since then.

Fast forward December end it was just itchy and that's it. Around end of January puss was coming out of my penis and it was burning like hell.
I went to doctor and without doing any tests he just gave me azithromycin 1mg and doxycycline for 1 week saying maybe it's Chlamydia or gonorrhea. everything got normal and after 15 days I started go get that itchy and burning feeling again in my penis. So I went again and this time we did PCR test and it came positive for ureaplasma. So now he prescribed doxycycline for 1 month but from this group I read about azithromycin and I took 2g before I started doxycycline and 2g after I finished my doxycycline. And yes I informed about this to my doctor and he said it's fine.
After completing 1 month I had to wait for 4-5 weeks before testing PCR again for ureaplasma. But I got this burning feeling back so I went to him he did normal urine test and he found something in my urine. Maybe urethratis but PCR is very expensive here so he asked me to wait till next time and then we will do it again.
So yeah after my urine test showed something in there he has now prescribed me moxifloxacin 400mg and flavoxate 200mg
I asked him about NAC after reading from here and he said it's okay take it if you want it isnt a big deal. told me to take 1200mg a day. And take it a little longer after I finish my treatment and start moxi a few days after I start NAC.
Stupid me also asked if I can take boric acid and lactic acid and he said it's for women you don't have vagina.

Help me I want to recover from it. I'm scarred big time after that burn I felt for first time in January. And there is no other men I can see who went through this and recovered.

Sorry I wrote too long but I guess we all know what it feels like once you have it and you have to take antibiotics for months and how they fuck with your stomach.
If anyone reading this I'm open to any tips or something which can help me overcome this.
For now I am taking it for 21 days and then get tested again for pcr.
Thanks.

i tested positive for ureaplasma last week and was prescribed doxycycline by the gyno, however i am confused by the treatment plan? she prescribed 2x 100mg on the first day of treatment, followed by 1x 100mg a day for the next 13 days.

i'm seeing most people online followed a treatment of 2x per day, should i be concerned by this? did anyone else follow a similar treatment plan? should i get a second opinion? i realise ideally i should've raised these concerns with her during the appointment, but i only did research online afterwards

Hi! Usually a lurker but just got some upsetting news. I got urea in 2024 for the first time and it took forever to find out what it was and a million antibiotics and co infections get rid of. Got it again I’m assuming around January of this year, might have been fall 2025 though not sure. Really never thought I’d deal with this again, it’s been hell and I hate how it puts a complete pause on love and dating. Constant pain, confections, and health paranoia ugh. I know you guys get it. Anyways did two courses of antibiotics this time around and neither cured it. Just got my test of cure back from 7 days doxi and then azi and it’s stilllll positive. I kind of had hope this time because I was like SURELLLY it’s gone NOW. Of course not! :D Anyways, we are going to do 14 days doxy now and then the normal azi after (it’s like 4 or 5 days of it I don’t remember but ya). Odds that will work? :( I have taken moxi before for this and couldn’t finish my course bc of scary side effects so I hope this does the trick.

PART NOBODY HAS TO READ JUST RANTING:
Can we talk about how hard it is to know if it’s just weird ureaplasma irritation or if you literally have an infection (uti yeast bv) you have to address??? At this point I’m gonna leave it alone because I’m going back on antibiotics and everything’s gonna get messed up again but I’m always just worried I have another uti and i don’t wanna like die lmao. Lmk if you resonate. I’d be in the doctor every week if I actually addressed it and I’ve already spent one billion dollars on this whole ordeal. SECONDLY: I literally leave in ONEEE day for seasonal work which I want to be excited for soooo bad I’m going across the country and won’t have access to medical care or testing like this and I’ll be on antibiotics for more than two weeks and i’m gonna like get a yeast infection or some shit and I also have a bit of gastritis so this is gonna fuck my stomach up more and i won’t be able to test again to see if it’s gone. I just want to be normal and do a normal fun thing i’m 22. Obviously going to try to not let it ruin my season because it’s such a cool experience but yk. It’s my health. Absolutely devastated, thanks for listening ! <3

Hey guys! I drive for work and I’m always usually working all day from 9am-5pm from my car. Will taking Doxy cause sunburning really bad? I know it says to avoid sun exposure but I can’t with my job. Thanks for any advice!

A little back story: I tested positive for ureaplasma urealyticum in October 2025. My OBGYN prescribed me Doxy twice a day for seven days, and once completed Moxi for 7 days.

My original symptoms:

-yellow discharge
-itching right at vaginal opening
-burning when peeing
-urine smell
-pain with sex
-and pretty severe pelvic floor pain

I took the antibiotics (which worsened the symptoms so bad!) and abstained from sex and went to pelvic floor therapy. i finally gradually started getting better.
I retested in January 2026, and was negative!! everything was great most of my symptoms were completely gone, and i thought i kicked it. (one thing that might be good to mention, the yellow discharge never went away, but i’ve read that’s pretty common)

I actually ended my long term relationship in January and hadn’t been sexually active in a few months, but about two months ago the vaginal itching reappeared. It is right at the entrance/base area (perineum?). The itching is pretty severe and drives me crazy. I wonder if my PH balance was off so i took some probiotics and boric acid suppositories, and the itch went away. So i didn’t really give it much thought.

Well current day, i recently met someone new and did have sex. (He’s been tested for all STDs i made sure before hand) And the itching is back, full blast. I have the awful itch, burning when peeing, weird urine smell, and still yellow discharge.

I’m so sorry for the long post, but I would really appreciate some advice! Should i be retested? Could this just be residual symptoms/flairs of residual symptoms? If so how should I treat? Any advice is greatly appreciated, thank you so much in advance!!