r/haematology

For reference of not on any medications that should cause this, I also have a history of autoimmune disease and epilepsy. The ER doctor said not to be concerned about this however, I didn’t quite understand it cause my levels were quite abnormal if anyone has any insight that would be awesome. I’m not on prednisolone or prednisone, either - off of my hydro chloroquine as well.

what do you make of it?

no biotin supplements.

can caloric restriction explain it?

Hello! I need some advice about my blood tests.
What do you think could be improved and how? Do you see anything immediately concerning?(besides the iron and vit D). Should I get any additional tests?
Disclaimer: I already talked to my doctor and I am on vitamin D and Iron supplementation. Starting magnesium today as well! For the phosphorus, I’ve been told only to eat salty nuts. Calcium to be tested tomorrow!

I’m a 30 y/o female. So at the end of March I had an episode where I felt faint and went to the hospital. They took my blood, and my white blood cell count was mildly high (15). From there, I followed up with my primary care who said eh prob a virus and reran my blood. Still high. CRP is also mildly elevated in case anyone knows what that is. They both go up and down but never normal. He then sent me off on my way to specialists. I’ve seen gastro, cardiology, hematology (3x), neurology, rheumatology and probably some other ology I can’t think of right now. I don’t feel good ever. Like not even an hour in the day. If I had a moment of feeling ok this would all be so much easier to handle. I have extreme fatigue, headaches, leg pain and sometimes low grade fevers upon waking. I also lost weight during this period, like a good amount - to which my primary care dr said “eat a burger”. He thought it was anxiety for the first 3 months. It wasn’t til recently that he changed his tune.

Ive had scans , bloodwork and anything you can name done by all these specialists. I have been through so much and it has been so stressful. My bf and I were SO close to getting engaged before this it hurts so bad. We also bought a new house during the time I was sick (i wanted to wait til I had my health figured out, but he convinced me it would be a good decision). So now I have a beautiful house that I still have boxes everywhere and cannot enjoy because I always am worrying and always feel like shit. I used to be a fun and energetic person and now I can’t do like anything. I can’t play pickleball or go to the gym like I used to.

On my bf, I also feel like my illness is ruining our relationship. We used to do sooo much fun stuff. Like weekend trips to wherever the hell we want. Travel, being active. We did sooo much. And now I’m too sick to do anything. I can go out to dinner or something like that but I’m not even having fun bc I feel awful. He is under so much stress with work and now he has a sick gf. Not even just a sick gf, one that has not been diagnosed and is going from specialist to specialist. It would probably be easier to support me if I had a diagnosis. There’s a special sense of hell of knowing something is wrong but not knowing what. Every specialist just says “not my area”. Someone is fucking wrong.

I worry about having cancer every day. I was tested for blood cancers but only the common ones I believe. I’ve had scans and no masses but what if they’re missing it. I worry about death. I worry that I’ll never feel good again. I do not want to die, in fact I want to live more than anything. I want my life back. I was so happy. But sometimes I think it would be easier to die instead of going through being a medical mystery. I miss myself so much. It’s been a bit over 6 months since I have felt normal. So long that I am grieving my life before this hell.

Another stressor is work. I really didn’t want to tell my boss, but I had to. I cried. I’m on intermittent fmla that only covers 1 day per week, and I only have 18 paid sick days left. My mom was hit by a car in April and I went on fmla for 2 weeks for her. That was at the beginning of this illness, and I didn’t feel good the whole time I was taking care of her. Thank God she is better now. But I am not. And now I have barely any fmla time. I am at work right now and I feel awful. I work in education and I was praying I would figure this out and feel better by fall because it is so busy and demanding. I do work a desk job bc though. If I had a physical job there’s no way I could show up. But every day is so fucking hard. I gag in the morning from anxiety. I wake up hot and feel sick but have to fucking go to work. I need the insurance. I have a mortgage now.

Anyway, this fucking sucks. If I make it out of this I will never take anything for granted again. When you are healthy you don’t realize the small things you take for granted. I really want to be healthy again. I want to be me again. I want to cook, clean, do activities.

Meal is depressing lean cuisine that I’m eating at work while feeling like shit. Thank you for reading. If you pray, any prayers would be appreciated. If you don’t, just good positive vibes would be appreciated.

Edit: I did not expect this to reach so many people. For those asking my wbc has been from 11-17 bouncing up and down. My crp the lowest was 5 highest 13.9 most recent 8. My platelets also are on the higher end going up and down from 300s-485.

I have had my vitamins checked. Ferretin was 14 but I brought it up to 70 with supplements. The hematoligst still prescribed iron infusions so I will get them done. She doesn’t think my symptoms match just low iron tho. And I don’t know why I’m iron deficient I have light periods and had a colonoscopy upper endoscopy so it’s not a stomach thing. Vitamin d was low but not too low 25 and I started to take supplements it went up to 47.

I’ve had an mri of abdomen and pelvis a brain mri and an mra of abdomen and all were ok the only findings were nonspecific.

I was tested for all tickborne diseases and had an extensive infectious workup.

I have no idea what is going to happen to me and I feel so hopeless and like giving up. but I just want to thank every single one of you that offered any type of suggestion or any reply at all. You have all made me feel less alone.!

I am feeling really defeated and pessimistic. I’m a 45yo F, I have been dealing w/extreme fatigue, heart palpitations, anxiety, hair loss, brittle nails & headaches/head pressure. I have had tons of labs done & had a couple head CT scans done, all found nothing. most labs look within normal range. I also have had my heart checked, EKG’s, worn a heart monitor. Also, in May of 2026 I had Gallbladder surgery (I had gallstones). I can barely function at work (I’m an elementary school teacher), I spend every weekday in my bed after work and weekends I hardly leave the house. I keep telling my Dr I don’t feel like myself, but then she says my labs look fine so I feel like to her I sound crazy. I’m taking Thorne Iron & Dr Ruth’s liquid Iron, but my ferritin hasn’t moved in 5 months. Her advice is just to stay the course and keep taking supplements. I started changing my diet and drinking apple cider vinegar before meals as well as food enzymes to help with absorption issues. I’m not anemic, but my Transferring Saturation is only at 21%. Seeking any advice that helped you raise your Ferritin levels.

I want to preface this with saying I am currently seeing a hematologist, so I'm just more curious if anyone has ideas, rather than this being a substitute for going to the doctor.

I started having consistently high platelets (between 5-600 k/ul) several years ago.  My PCP finally sent me to a hematologist about a year ago,  who assured me they would "figure it out". Which they obviously haven't,  so now I'm just going on every 3 months for tests to see if they go back down on their own. They have run many tests,  including a bone marrow biopsy, and found nothing. Anyone have any thoughts?

I've had scattered but not crazy out of range abnormal results (like, 1 or 2 tests out of 4) for the following: c- reactive protein,  manual and auto neutrophil, monocytes, sedimentation rate, auto immature granulocyte, MCHC, and reticulocyte. Some but not all of the tests have found abnormal platelet morphology and giant platelets.

My iron has consistently been weird (see pics).

I have high cholesterol and am in perimenopause. The only medication I'm taking that I think would affect my results is oral birth control? Happy to share any other test results.

Normal results:

B12

Uric acid

Beta2 microglobin serum

Calcium ionized

Potassium plasma

Protime-INR

APTT

Folate

Lactate dehydronase

Haptoglobin

TSH

Vitamin d 25 hydroxy

Hemoglobin a1c

Lipoprotein A

Erythropoietin

Negative for:

Ana

Rheumatoid factor

Jak2 exon12 gene mutation

Calreticulin gene

Mpl mutation

Brc/abl qualatative

Flow-lymphoma/leukemia

Chromosome analysis: oncology

Point heme ngs panel

For context: 34F with chronic fatigue that has been especially bad lately. I've had a myriad of symptoms for 10+ years which I just attributed to my body being messed up from my history of Lyme and long Covid, like dizziness, brain fog, easy bruising, hair loss, body aches, skin conditions, joint pain with loud cracking/popping sounds, food sensitivities, my stomach and gut being pretty much wrecked with chronic gastrtis and IBS type symptoms. Negative tests for chrons and celiac disease, normal colonoscopy, endoscopy just showed gastrtis.

I had dysautonomia for two years when I was going through long covid but that has gotten a lot better. I was diagnosed with mild hEDS two years ago. Also for the past few months I've been having hormonal issues that feel like estrogen dominence, getting tested for that soon. I've also been experiencing memory loss lately which is a new one for me, I've been on Wellbutrin for a year so I've been assuming it might just be from that since I've read a lot of others have experienced that with it.

I'm guessing a lot of these symptoms might not be related to these test results but figured I should include my full health background.

I became a vegetarian a few weeks ago, that's why I asked for my iron levels to get checked thinking my worsening fatigue considering my only sources of iron are non-heme iron and I don't take iron supplements. I was fasting for 18 hours when I took the test. I was suprised to see my iron work up, thought it it would be the opposite. I have another appointment with my doctor next week to go over results and likely get nore testing done but I'd like to get opinions on here while I'm trying to wrap my head around this is in the meantime.

My doctor ordered the Von Willenbrand test earlier this year for the easy bruising, she sent the results over to specialists who said since it's not that low it might just be from hEDS and it would only maybe be a concern if I ever had surgery done. They also said it might be from being on an SSRI, but I'm not on one lol not sure where they thought they saw that in my chart.

Oh and my Ferrirtin is the low end of normal at 32. My MPV and platelet count are always a little low, same with my white blood cell count, doctors always say it's just my normal baseline but I'm curious if all these results together might point to anything.