r/seroquelmedication

From IR to XR wanting to go back to IR

You guys I was prescribed 300mg immediate release for 2years then it went out of stock feom my pharmacy they switched me to XR without asking or anything, not even a day goes by I can tell the difference … my brain is feeling not like on the same drug . My question since the med is out of stock feom the country as whole . How can I get the same effect as I used to do on IR?

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u/Shot_Brush_9668 — 8 hours ago

Munchies.

I’ve been taking Quetiapine most of my adult life. I currently take 300mg IR.

When them munchies hit, (especially at night). They hit hard. After a bit of trial and error, I’ve found out one thing that works for me and that’s anything with protein in it. Rice pudding with protein especially. It’s sweet, it’s heavy and it fills me up. I buy it from the Supermarket.

Discovering this has helped me stop munching through the night-especially if I wake up in the early hours. Sometimes I have 1 tub, sometimes I have 2.

I wish the Doctors would have told me about this years ago! It would have saved a lot of frustration.

Now, some brands of protein products taste horrible to me but like I said, with some trial and error, I’ve found the ones I like.

I thought I’d share what works for me because it might help someone else who thinks they’ve tried everything.

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u/natnat301 — 12 hours ago

Seroquel and alcohol

Not sure if this is a stupid question but does anyone know how to feel less "sick" when drinking on quetiapine?

When I was on 75mg I had no issues drinking while taking my dose on time. Now I'm on 325mg and every time I have even a couple drinks I start to feel very nauseous, dizzy and unwell. If I take my usual dose after drinking in the past few hours the dizziness and nausea gets way worse.

Does anyone know how to help that feeling? I know I'm not supposed to be drinking but I always end up drinking anyway I'm just wondering if anyone has any suggestions to feel less shit.

I've tried eating more before drinking, not eating, drinking lots of water, I've tried taking metoclopramide or domperidone. Didn't help.

Or can I just build a tolerance to this feeling over time?

I usually drink soju. Sometimes vodka.

I know I'm going to drink anyway, I'm just trying to reduce harm and discomfort to myself as much as possible when I do.

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u/Emergency-Gap-995 — 13 hours ago
▲ 8 r/seroquelmedication+1 crossposts

Scared to go back on seroquel

I took seroquel (100mg) for maybe over a year until I realized how much less drowsy I was without it. I would take it as early as 7pm and still barely be able to get out of bed until after 11am. Now that its been a good several months without it, I see it may be worth going back on it simply to improve my worsening mood. I just really really REALLY dont want to. I cant deal with the drowsiness and it did not go away after a few weeks like they said it would. Im scared of how much more I'm gonna be sleeping and how tired Im gonna be when Im awake. Has this happened to anyone else? If it did how did you manage? I'm even considering staying off it and finding some other non med related way of improving my mood.

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u/09141983 — 24 hours ago

Does the fatigue get better

I’ve been on 100mg for a week after a manic episode and moved from 25mg. I’ve been sleeping over 10 hours a day and genuinely just can’t move. I sometimes can get the energy to go for a walk or do something easy then I just end up collapsing on the couch or floor even and just feel so ungodly sedated all the time. I can’t think or do much

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u/spycat500 — 1 day ago

Tapering off Seroquel, after 6 weeks..

I been on Seroquel for 6 weeks and decided to taper my daytime dose to 12.5 and leave my nighttime dose at 25mg for now.

I am on my 3rd day on these changes and I believe I just experienced my first insomnia rebound..?

I couldn't sleep at all, I am tired but I just couldn't sleep, no racing thoughts, nothing.

I was originally prescribed this medication because of my panic anxiety attacks I had after an abortion, I didn't know much about the changes of hormones and how impactful they could be.

I been doing pretty good managing ever since then but Seroquel even though it helped me thru the nights which I appreciate it for, daytime wise has been so bad, it brought me more anxiety in the first 2 weeks and severe depression and anhedonia, now after 3 weeks it has only been sedative and annoying brain fog and numbness.

I heard this medication has horrible side effects and withdrawal symptoms and I decided to start tapering and if possible try a different option at least if I have more anxiety later, but even at 6 weeks you still get withdrawal symptoms!

Do you guys who take or know anyone that takes Seroquel how long this might last? and how did you combat the sleeping difficulties? I rather have anxiety all day than no sleep for months...

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u/moonpie_addict — 1 day ago

Quetiapine ‘super-responder’

Hi,

I take 100mg of Seroquel for mild depression and it works really well, I’ve been depression free for almost one year. The depression actually lifted at 25mg however I had the dose slowly increased to address anxiety which it hasn’t helped with so much.
Is any one else a quetiapine super-responder?

Conventional antidepressants didn’t work for me at all ie SSRIs and mirtazapine. I think I might have Cyclothymia or even hyperthymia + depression , although I am not a 100% sure of myself, that is a total self diagnoses, my good mood isn’t episodic, it’s seems consistent. Medical professionals give me the feedback that my speech seems pressured. my perceptions are altered so that music and colour seem very beautiful. I have energy.

The sad thing is I forgot this part of myself. I hated how I felt but didn’t explicitly realise I was depressed

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u/biggobcantstop — 1 day ago

Ho dormito 16 ore dopo aver preso quetiapina è normale?

Non tutte di fila mi sono svegliata qualche volta dopo 10 ore, poi dopo 3 e dopo altre tre però volevo sapere se è normale così ?

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u/jupical2 — 1 day ago

Is it okay to both take seroquel for sleep and ADHD medication in the day time?

Since I have insomnia and I have heard about seroquel in low doses and it’s help on insomnia I would like to know if it would be fine to use even tho I also use adhd medication in the day time.

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u/Square-Meal-9238 — 2 days ago

Is my tolerance too high?

Prescribed for bpd mood swings about 2/3 months ago. Currently on 100mg İR twice a day. I genuinely haven’t noticed anything. Not even side effects I was warned about. My sleep is still terrible (can never sleep till 5am then oversleep in the day), and my appetite has noticeably DECREASED. Not to mention I have engaged in risk taking behaviours still and been very impulsive at times. Feel like Im swallowing a tic tac every morning, I just can’t spot any effect

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u/sheeniebeanie1 — 2 days ago
▲ 4 r/seroquelmedication+1 crossposts

prescribed seroquel for anxiety/ruminating thoughts but had weird auditory side effects, should i try it again?

i’m 18 and i was prescribed seroquel/quetiapine early on for anxiety and obsessive/ruminating thoughts, but i’ve only tried it twice because both times kinda scared me.

first time i took 25mg i got bad tinnitus/ringing. second time i took it, it was more like this weird tv static type sound that wasnt normally there, and it didnt feel like normal tinnitus either. it freaked me out enough that i havent taken it again.

she also recommended that I could even take 2 but the thought of hearing something again makes me more anxious.

i’m also on zoloft/sertraline 100mg and i’ve been on this dose a little over 6 weeks now. i’m still dealing with a lot of anxiety and obsessive thoughts/rumination, and my next doctor appointment isnt until the 22nd, so i feel kinda stuck.

i’m not asking anyone to tell me what to do medically, but has anyone else had weird auditory stuff from seroquel, especially at a low dose? I’m not and have never been schizophrenic. did you try it again or stop and ask for something else?
i’m gonna bring it up with my doctor either way, but i’m honestly not sure if i should even try taking it again after that happened.

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u/Competitive-Road3005 — 2 days ago

awful side effects while taking seroquel, is this normal?

i’ve been on 300mg for half a month and i’m still not used to it. i take it before i go to sleep and get all twitchy and paranoid when it kicks in. the other night i believe i experienced auditory hallucinations. when i do fall asleep, i sleep for 10-12 hours and it’s impossible to wake up. i feel sluggish and exhausted throughout the whole day. i feel like i can’t remember anything. i’m easily irritable the next day as well and i just want to be left alone and lie in bed. i have barely any motivation and i don’t really feel like it’s helping me mentally, it’s just suppressing my emotions. ive skipped doses a few times because i forgot to take it and skipping a dose makes me extremely depressed and nauseated. i feel like this medication is making my life worse. what do i do? does anyone else feel this way when on this medication?

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u/Previous-Rock1806 — 3 days ago
▲ 2 r/seroquelmedication+1 crossposts

Rapid cycling depression, I have rapid cycling depression post partum

I have been having 2 weeks of horrible depression followed by 2 weeks of feeling ok, on a cycle, ever since the birth of my child, I’m curious if anyone else has this or experienced this.

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u/LumpyRun3566 — 3 days ago

Has anyone noticed any side effects relating to their sexual function?

I started Seroquel recently and am on 150mg which has helped with my sleep and mood, however I've noticed my libido is lower. I am not sure if it's the medication as my libido flucuates a bit.

I wanted to find out if it was normal for most people to have some libido side effects.

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u/InsideMuch4907 — 4 days ago

Has anyone else had a positive experience with Seroquel?

Whenever I read about Seroquel (quetiapine) online, especially here on Reddit, it seems like almost every story is overwhelmingly negative. People often describe severe weight gain, feeling like a zombie, or having all kinds of terrible side effects.

My experience has been very different. I’ve been taking 100 mg at bedtime and honestly it’s helped me a lot. I sleep much better, I feel more stable overall, I haven’t gained any weight—in fact, I’ve actually lost weight—and I haven’t experienced most of the side effects that people often talk about.
I’m not saying those experiences aren’t real, but I’m wondering if there’s a bit of a selection bias, where people with negative experiences are naturally more likely to post.

Is anyone else here doing well on Seroquel? I’d be interested in hearing from people who’ve had a positive or neutral experience too.

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u/SomewhereBusiness368 — 5 days ago

Psychiatrist on high horses and not listening

Ive had three Psychiatrist's in my lifetime. Each one is so fast to put me on a pill without making sure my diagnosis is correct. So I end up being a guinea pig for a few months. Me having my mental issues trust them until they do something and I lose that trust. They talk to to for most of my sessions about their own life problems. Give me a new pill and send me on my way. I am Autistic with ADHD. But was given a diagnosis of Manic Depressive Disorder. I’ve seen a few doctors who didn’t even take the time to make sure that was the right diagnosis. Anyone else have this issue with Psychiatrists?

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u/Mooinmytribe555 — 3 days ago

24M - Stopped Seroquel 10 days ago and now I feel extremely sensitive to stimulants/dopamine. Is this normal?

Hi everyone,

I’m a 24-year-old male with a psychiatric history of anxiety. My only other diagnosed medical condition is fibromyalgia, for which I take Cymbalta (duloxetine) 60 mg daily.

I’m honestly starting to feel like I’m losing my mind, and I’m hoping someone has been through something similar.

I was taking Seroquel (quetiapine) 50 mg every night for sleep since December 2025. It was prescribed by a different doctor than my psychiatrist, who had originally prescribed trazodone (50-100 mg) for sleep. About 10 days ago, I stopped taking the Seroquel because I really didn’t like how it made me feel before falling asleep. Instead of drifting off naturally, I always felt like I was about to pass out or die right before I fell asleep. It wasn’t a smooth transition into sleep. Trazodone wasn’t a great option for me either because it significantly increased my appetite.

Since stopping Seroquel, I feel like my brain has become extremely sensitive to anything stimulating.

For example:

My ADHD medication now causes episodes of very high blood pressure.
Even caffeine causes my blood pressure to spike.
I have clonidine prescribed for high blood pressure, but it dries my eyes out so badly that I hate taking it.
Hydroxyzine helps me sleep, but it also causes severe dry eyes and even makes me notice specks in my vision.

What worries me most is that it feels like my brain has become overly sensitive to dopamine. I’m wondering if stopping Seroquel has temporarily changed my dopamine receptor sensitivity, and whether it’s also making me more sensitive to my Cymbalta.

My worst symptoms are:

Blood pressure spikes (I’ve measured readings as high as 149/105)
Feeling my pulse pounding in my head and even my eyes
Muscle tension
Confusion
Difficulty speaking during these episodes

These symptoms are especially noticeable if I consume more than about 200 mg of caffeine (which is still below the FDA’s general limit of 400 mg/day for healthy adults) or if I take my ADHD medication.

I know the obvious answer is to follow up with the doctor who prescribed the Seroquel, and I do plan to. I’m just hoping to hear from anyone who has experienced something similar.

My main questions are:

Has anyone experienced becoming much more sensitive to stimulants or dopamine-related medications after stopping Seroquel?
If this is withdrawal or receptor readjustment, how long did it take before things returned to normal? Are we talking weeks or months?
Did anyone end up restarting Seroquel, and if so, did it help?
Is there any legitimate concern about developing Stevens-Johnson syndrome simply from restarting quetiapine after being off it for about two weeks, or am I worrying unnecessarily?

I really appreciate any experiences or advice. This has been incredibly distressing, and I’m trying to figure out whether this is something that will improve with time or whether I need to consider restarting the medication.

Thank you.

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u/ReplyGlobal — 4 days ago