Familial hypercholesterolemia? LDL 202 / Cholesterol 273 despite weight loss and normal A1c
Just got my fasting lipid panel back (12-hour fast). I’m a 40-year-old male, 5’11”, 181 lbs (down from 240 lbs over the past year on Mounjaro 15 mg).
Results:
Total Cholesterol: 273 mg/dL
LDL: 202 mg/dL
HDL: 43 mg/dL
Triglycerides: 139 mg/dL
Non-HDL: 229 mg/dL
Other relevant labs:
HbA1c: 5.19%
AST: 18.9 U/L
ALT: 16.3 U/L
Creatinine: 0.99 mg/dL
My physician recommended starting rosuvastatin 20 mg which I’ve already done. I haven’t had ApoB or Lp(a) checked yet, but I’m planning to.
Given that my LDL is still over 200 despite major weight loss and otherwise normal labs, I’m wondering if this points toward a genetic cause like familial hypercholesterolemia.
Has anyone had a similar profile, and how much did your LDL drop on rosuvastatin 20 mg?