u/AdvertisingWinter102

What do you think about the medication Amenamevir ?

Recently, Alfasigma contacted me to participate in a clinical trial for their new treatment, IM-250. Unfortunately, my current situation does not allow me to participate.

If you’ve read my other posts, you know that I actively fight for herpes awareness and for better recognition of the real impact this virus has on people’s lives.

That is why I am reaching out to everyone. I want to bring people together and show that this virus truly affects millions of lives.

If anyone would like to take my place or receive more information, I would be happy to connect you with the company.

Please share and help make our voices heard.

I’m unable to post the photos here, but I can share them with you. If you have any questions, feel free to write them in the comments.

According to available sources, BDgene currently appears to be the only company to have reported cases of clinical cure for ocular HSV-1 herpes.

I need your help to sign petitions sent to several organizations to show that we are present and united. Please also read my other posts

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BDgene's answers

I hope this message finds you well.

Thank you very much for your continued interest in our BD111 therapy and for your support in advancing medical innovation. We truly appreciate the enthusiasm you have shown toward our research.

We are pleased to share that BD111 has now advanced to Phase II clinical trials. This is an important milestone in its development, and the current phase will focus on further evaluating the therapy’s efficacy and safety in a larger group of patients, as well as optimizing dosing regimens.

That said, we regret to inform you that, at this time, participation in the clinical trial remains limited to patients with Chinese nationality. This restriction is due to regulatory requirements and operational considerations specific to the current stage of the study.

We understand this may be disappointing, and we truly appreciate your understanding. We remain hopeful that, as the trial progresses and expands, there will be more opportunities for broader participation in the future.

If you have any further questions or would like to stay updated on future developments, please feel free to reach out. We value your interest and look forward to sharing more progress with you as it becomes available.

Wishing you all the best.

Sincerely,

Hello,

I would like to know if there are any ways to purchase medication without a prescription and have it delivered to Canada, please ??

Herpes affects billions of people around the world, many of whom suffer in silence, paralyzed by the fear of judgment and forced to endure their distress in isolation. Yet, very few dare to stand up and demand real change, support petitions, or put pressure on institutions to accelerate scientific research.

It is striking how rarely people speak about herpes… until the day it affects them personally. Where are these nearly 3 billion people living with the virus? In my opinion, if everyone affected united their voices, signed petitions, and raised greater public awareness, things could take a very different direction ??

https://www.sciencedirect.com/science/article/pii/S0166354225001974?utm\_source=chatgpt.com

https://www.sciencedirect.com/science/article/pii/S0166354223002115?utm\_source=chatgpt.com

According to my research, IM-250 (Ibervir) may be able to effectively penetrate nerve ganglia, where HSV remains in a latent state, which is a potentially encouraging observation. Furthermore, some data suggest that this molecule may act on the latent virus present within these ganglia. However, to date, no study has demonstrated that it is capable of completely eliminating the virus.

It has nevertheless been observed that after treatment, the amount of viral DNA detected in nerve ganglia may be reduced, and further studies are currently underway to better characterize these effects.

In this context, do you think this could significantly reduce the overall viral reservoir present in the nervous system?.

Why are promising HSV treatments being abandoned?

Several companies have discontinued their research programs targeting HSV-1-2, and keratitis, even when some projects had reached advanced stages of clinical trials (Phase II and III).

The most commonly cited reason is a lack of funding and commercial viability, despite encouraging results in certain cases.

Examples of discontinued programs:

• Moderna — mRNA-1608

• Genocea Biosciences — GEN-003

• Anteris Technologies (Admedus) — HSV-2 DNA vaccine

• Amgen (via BioVex) — ImmunoVEX HSV2

• Mymetics — HSV vaccine

In several cases, the clinical data appeared promising, yet the programs were not continued or taken up by other companies.

This raises an important question:

Is the barrier scientific, or primarily economic?

Why are so few initiatives stepping in to continue or revive these projects, despite the medical need?

Excision BioTherapeutics

BD Gene Therapeutics

Fred Hutch Cancer Center

Here are three organizations working on developing a curative treatment aimed at a complete cure. We must encourage them to launch campaigns, create petitions, and engage with your regional representatives. Make your voice heard.

Hello,

For those who suffer from keratitis, what methods do you use to relieve the pain, please?

Hello,

For those who suffer from keratitis, what methods do you use to relieve the pain, please?

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Do you know how to buy medication without a prescription, please?