What do you suggest for the true treatment resistant depression?

For people with severe depression who have tried and failed dozens of meds, most therapy modalities, TMS, ketamine, ECT, diets, exercise, etc, what do you suggest they do?

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u/Syruponmypizza — 3 days ago

What do you suggest for the true treatment resistant depression?

For people with severe depression who have tried and failed dozens of meds, most therapy modalities, TMS, ketamine, ECT, etc, what do you suggest they do?

reddit.com
u/Syruponmypizza — 3 days ago

It's wild how dysthymia is categorized as "mild"

I've been diagnosed with MDD and dysthymia, but I feel like I have some super depression. I know most people would just call what I have double depression, but it's not scientific. I guess then again neither is the DSM.

Been severely, not mildly, depressed for years.

Sorry just a little vent I wanted to put out into the world

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u/Syruponmypizza — 3 days ago

CMV: a psychiatrist and a monkey have an equal chance of prescribing an effective medication for someone with depression

If 5 different antidepressants were put on a table, let's say Lexapro, Prozac, Zoloft, Celexa and Paxil, a monkey would have the same chance as a psychiatrist in prescribing one that would help a depressed person.

Several assumptions:

Let's assume instructions for taking, titrating, etc are all included with each med.

Of course each medication comes with a different side effect profile. But nobody has any idea of knowing what side effects an individual may or may not experience.

Let's assume the patient is medication compliant and doesn't forget to take it.

Also let's assume the patient is not taking any other medications for any other conditions (beta blockers, pain meds, etc)

My thesis refers to the therapeutic benefits specifically.

Reasoning:

Prescribing psychiatric medication is entirely trial and error. There have been copious studies with percentages across large populations, but when it comes down to the individual, because there are no biomarkers for depression, and diagnosis relies entirely on an arbitrary set of observable or experiential criteria, those percentages can be thrown out the window.

There is not a person on the planet who can accurately predict for the individual what antidepressant (if any at all) will help reduce or eliminate presenting symptoms.

Edit: most of the replies go beyond my initial statement. Of course in the future once there is more information available (eg were there side effects) the psychiatrist will be able to make better decisions than a monkey. Hell a middle schooler probably could compared to the monkey.

My point is that for that very first medication trial, given 5 options, that for the sake of argument we'll see 100 psychiatrists narrowed down the initial treatment to one of those 5, the likelihood of a psychiatrist choosing the correct one of those 5 for the patient is the same as if a monkey chose it

Edit 2: I think I'm all done with this one. Thanks to everyone for contributing. A lot of people seemed to be hung up on what happens after this initial trial, or how we got to the initial trial. That wasn't what I was asking to have my view changed about because I was in agreement with most if not all of those folks.

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u/Syruponmypizza — 6 days ago

Transition suggestions?

The billionth time this has probably been asked, but any suggestions are welcome!

u/Syruponmypizza — 8 days ago

Are Varroa Check containers supposed to leak when shaking?

I've used a brand new one once and now no matter how I screw the lid on it just leaks out the top whenever I shake

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u/Syruponmypizza — 15 days ago

Do people here not believe mental illness is real?

As someone that absolutely is mentally ill, I get confused when I see people here put mental illness in quotes.

From personal experience it is absolutely 100% real. Where it comes from also differs from person to person (biological, social, environment, etc)

I believe that psychiatry as it exists is the least successful and most harmful discipline in the medical world. This stems from a lot of things but primarily lack of understanding

Edit: thanks everyone for contributing. It seems I'm on the same (or similar) page as most people. Except the stars guy. IDK about that one

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u/Syruponmypizza — 21 days ago
▲ 51 r/Vent

5 years ago I had a routine surgery, a med I was given ruined my life

I was almost 30. Had essentially the exact same surgery a year prior with no complications.

No history of mental illness. Since the surgery I've had crippling MDD PDD OCD and PTSD.

I have no intent to harm myself or others, but I literally think about it everyday, constantly.

Medically disabled since then.

Folks, PSA, metoclopramide/reglan may help some people, but the harm it can cause FAR outweighs any benefits it can bring. Please stay far away from it and any other dopamine antagonist antiemetics.

(I went back and reviewed all the meds I'd ever been given before, and this was the only class of drug I'd never received in my life)

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u/Syruponmypizza — 25 days ago

If a doctor prescribes a med, does a nurse have to use that one?

I have a general question. It probably depends on facility policy, but I would imagine it's mostly the same everywhere.

If, for example, a doctor prescribes one antiemetic for a patient after a surgery, can a nurse give a different one at their discretion? Or is the nurse required to first use the one the doctor ordered?

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u/Syruponmypizza — 29 days ago

Is the polestar discontinuation in NA really a big deal for any maintenance and repairs?

I was just about to buy a polestar 2 today, but I've been reading so much about this on here and it seems largely uncertain.

Can't Volvo dealerships just do any repairs and maintenance?

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u/Syruponmypizza — 1 month ago

How do you lift boxes up when the frames of the top and bottom box are stuck together from ladder comb?

Running a 3 deep system. My top deep is almost entirely honey so heavy AF.

It's got a ton of ladder comb connected from the bottom of the frames to the top of the frames on the middle box. So when I try to take the top deep off it's stuck..

I thought about twisting but wouldn't that kill a ton of bees?

Any help is much appreciated! 1st year noob here

Edit: thanks everyone for the comments and information!

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u/Syruponmypizza — 1 month ago

Hive swarmed yesterday I think :/

Was wondering why one of my hives was bearding so much and the other wasn't. There seemed to be quite a few girls buzzing aimlessly overhead that didn't appear to be orientation flights.

Opened up my hive and found a bunch of swarm and supersedure cells. A few charged.

Couldn't find the queen, but there were eggs in there.

Close it up and leave it for a few weeks?

u/Syruponmypizza — 1 month ago

New AC unit took 3.5 hours to cool 2 degrees?

Recently had a new AC unit installed in my 900 sq ft house.

At 1015a it was 71° in the house, set the thermostat to 69°. It didn't get to 69 and shut off until 145p.

The outside temperature during this time frame was 72-78°. Low humidity.

Unit is a 1.5 ton 14.3 SEER2 Carrier.

Is something wrong? It feels like it should have taken an hour to bring the house down to 69°.

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u/Syruponmypizza — 2 months ago

Just bees doing bee things?

IDK if one was trying to rob or what..

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There were 3 doing this before I started filming

u/Syruponmypizza — 2 months ago

Had swarm cells, didn't do anything with them, now the cells are gone and they didn't swarm?

I'm assuming this is a classic case of "the bees know better than us".

​

I recently posted with pics of a few swarm cells. I decided not to do anything with them. Just inspected the hive... it's thriving, they didn't swarm, and all of the Queen cells are gone.

​

I did add a super, but they didn't even start drawing comb on it.

​

Did they just say we're actually ok here no need to leave?

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u/Syruponmypizza — 2 months ago