r/Mirtazapine_Remeron

i've been on mirtazapine for about 3 years now (started at 7.5mg, at 15mg now and about to increase to 30mg in a week) and it has truly saved my life. it was prescribed to me for appetite and anxiety/depression, and it has worked wonders. the only side effects i had on this med was craaazy drowsiness, like i was sleeping A LOT when i first started on 7.5mg lol, but it was a good thing because my sleep was crap. i don't get drowsy anymore, but it still works well for my appetite and anxiety/depression. thought i would share my positive experience with mirtazapine in case anyone is feeling afraid of taking it for the first time. 😊

Hi! Just for context before I start, im 19f, and i got prescribed 30mg of mirtazipine to take every night for my anxiety and eating disorder. I started it around mid July (probably around the 13th), and it was helping for a while. Now however, my resting anxiety is higher, Im waking up in panic attacks every morning and sick all the time. My IBS has been flaring like crazy. I also have panic disorder, bpd, and agorapbobia along with anxiety. And me and my partner are currently renting a super small room in a place thats super unsafe. So that's also obviously adding.

My question is, should I try and stick it out for a few more weeks, or should I really push to switch medications now. Whenever I miss a dose I will be in a huge panic attack until I can take them, so I also know the withdrawals would be brutal. So im just stuck. Help or advice would be appreciated 👏

Hi all,
So I’m on 60mg elvanse and have started 15mg mirtazapine around 3 weeks ago. I’m waiting for CMHT assessment so for now just have the gp.
The gp suggested increasing the dose of mirtazapine to 30mg as it isn’t doing anything and my self harm suicidal thoughts etc are increasing.
However she seemed to be quite worried about the risk of serotonin syndrome.
Now I am overthinking it and I’m really stressed because obviously it can be life threatening but also if I get it I will have to stop both medications. The 2 meds combined are the only reason I am still here so having to come off them both would actually be the nail in the coffin.
Gp is chasing CMHT to try and bring the appt forwards because it isn’t until 21st sept but does anyone else take this combo of meds?
Has anyone ever had serotonin syndrome what if I have it but I don’t know I do? What happens in terms of medication does it just mean all medication affecting serotonin in the future is off the cards?
Anyone’s experiences are so appreciated because I am spiralling about it all

Basically, I started this drug at 15mg eventually went up to 45mg after doing 30mg for two weeks as well.

I then decided it wasn’t doing anything for me and decided to taper, down to 30mg for two weeks then 2 days at 15mg. I’ve now stopped for around 2 weeks

Since around 6-7 days ago I’ve just had constant palpitations and funny flutters in my chest sending my anxiety wild, anyone else experienced this and how long did it take to subside?

It took me forever to book myself a psych appointment. They prescribed me mirt since I’m underweight and another that I didn’t start yet. I took mirt for a week and it made me constipated which I would have been able to deal with fine if I knew the effect was temporary but apparently it isn’t. According to online it doesn’t really go away on its own but you can mitigate it by drinking lots of water and fiber and then laxatives if that didn’t work. I didn’t wanna live like that. I know you’re supposed to drink 8 cups of water a day anyway but I didn’t wanna live worrying everyday if I’m drinking enough water just to be slightly less constipated then I was. I also was not gonna have laxatives and stool softener be apart of my regular life routine especially because before I started mirt, I never had any issues with this.
I only lasted a week on mirt and then I almost started crying because I was frustrated with not being able to shit and how I hated that this was something occupying my mind all day when I was supposed to be enjoying myself and I decided that I just couldn’t take it anymore. I was literally only on it for a week.
I hate that it took me forever to make an appointment and after only a week im right back to where I started. It’s also frustrating because constipation was the only negative side effect. I liked having a bigger appetite and being tranquilized at night.

I’ve been taking mirtazapine 15 mg for about a week, but I still have no appetite and I’m struggling to eat enough. I’ve also been losing weight.

For those who took mirtazapine for appetite loss: how long did it take before you noticed an increase in appetite? Did anything else help you eat more?

i’ve been on mirt for only two days with a follow up planned with my doctor for a week after being on it but i’m suffering so badly. i’m heavy, dizzy, can’t form sentences, the brain fog is awful and i’m still waking up every hour in my sleep but now with added panic because i can hardly move my limbs, they feel so weak and shaky. i’ve been monitoring my blood pressure and it’s bouncing around between normal and low but never under like 100/62.

unsure if i’m just being too sensitive and need to stick it out or if these are signs this medicine isn’t for me- i’ve spent the last two days in bed because i can barely keep my eyes open but can’t actually fall asleep because im not tired i just feel ill and weak and heavy

oh and i can’t stop thinking about food despite not feeling hungry

(i am NOT asking for medical advice! just other people’s experiences!!!!!!! also this isn’t typed by ai. i just like using em dashes.)

hello!! here’s what’s wrong with me: i have suspected heart issues, undiagnosed—but i do have frequent heart palpitations, more than likely from the severe anxiety and panic disorder that i suffer from.

i have had bad history from almost every other antidepressant. i’m very hesitant to try this cuz i also have a fear of taking medicine in general.

im on clonazepam right now for anxiety, take when needed which is basically every day. should be taken into account that i have extremely debilitating social and general anxiety, AND panic disorder. all of these keep me from going into jobs, etc etc etc. all the works. :—/

TLDR!!! i just want to know if mirtazapine has messed with any of yalls, or if it famously does, heart rate. specifically with your QT.

Hello, I thought I’d post in here to see if anyone has had a similar experience.

I’ve been taking Mirtazapine 15mg for 4 years. It was originally prescribed to me to increase my appetite and help with insomnia. It definitely helped my insomnia, and I suppose helped me prevent losing weight but I never really had any big weight gain from it either.

A bit of background, I got diagnosed with OCD a few years back, more specifically relationship OCD. Had a couple long term relationships fall apart as a result, and went deep into therapy etc and have gotten a lot better. These past couple of years, I now have a wonderful relationship with someone I am planning to marry, and really don’t struggle with my OCD like I used to. I still go to therapy monthly, I live a healthy lifestyle, and don’t have any pressing stressors in my life as of late. I also don’t take any other medications.

Back to the mirtazapine, I got sick about a month ago (cold, maybe Covid) and neglected to take my mirtazapine during the cold. I’ve been wanting to stop taking it due to the grogginess and difficulty waking up when on it, and because my appetite has improved. I also am the type of person where I’d rather not be on any medications if I don’t absolutely need it. I concluded that my issues with appetite/insomnia were more related to my OCD and the constant anxiety that it brought me in the past, and since I have gotten so much better, I thought I could handle my appetite and sleep without the mirtazapine. I had been sick for like 4-7 days and didn’t take the mirtazapine, and was eating and sleeping fine, so I decided to just continue not taking it.

I have been off the mirtazapine for about a month now. The first two weeks of not taking it, I literally felt no change in anything and no withdrawal. I am eating fine, falling asleep and staying asleep fine, and felt good in terms of my mental health. However week three, I started to get some light to moderate anxiety, and some light depression (lower motivation, feeling flat, seeming to care less about pretty much everything, minor depersonalization, etc). However, even up to today I’m still eating and sleeping normally. With the anxiety and depression, it also comes in waves. I feel pretty lousy in the morning, then might feel pretty good in the afternoon, then back to lousy in the evening, etc.

I’m just concerned and confused. I’ve put in so much work on my mental and physical health, and my original reasons for taking mirtazapine (eating, sleeping) are resolved as of now. But this newfound anxiety, depression, etc. is really bothering me and making me worried. I just don’t feel like myself. And it’s weird too, because you’d think the withdrawal from stopping a medication like this would be more acute, and get better overtime. In my case, it was fine for a couple weeks, and then I have started having these dips in my mental health during weeks 3 and 4. Although I did have anxiety as a result of my OCD in the past, that wasn’t even the reason I got prescribed mirtazapine in the first place. Even with my history of relationship OCD, my newfound mental health struggles after stopping mirtazapine aren’t directly affecting or attaching to my relationship. My girlfriend is wonderful, she is aware of what I’m going through, and has been a healthy and constant support system for me.

To wrap this up, has anyone experienced delayed mental health effects after stopping mirtazapine? The only two things I can think of that are causing these new mental health struggles are:

1. Stopping mirtazapine. Even though these symptoms didn’t manifest for at least two weeks after stopping.

2. (This might be a stretch), but I also have been made aware of mental health issues after COVID, and wonder if when I was sick that’s what I had, and now have some neurological long-covid type symptoms.

Any help or perspective is much appreciated. I’m hopeful I will make it through this, but am also scared that something isn’t quite right.

I’ve been on 100mg sertraline and 15-30mg of mirtazpine for a long time.

It’s a good combo for me it works except in sick of the mirtazapine weight gain

Has anyone successfully swapped out mirtazapine for bupropion?

Thanks for reading I appreciate replies

When I am desperate for sleep I use a mirtazapine

I read about how smaller doses are better for sleep

So I split my 30mg tablet in two

Would it still be effective split into three??

Any advice appreciated as I only have one left

Hi fellow Zoloft users. I’ve been on 150mg for a while now and been on sertraline for over 4-5 years in general. For months and months I’ve been consulting back and forth with my GP whom recently contacted a psychiatrist for advise regarding my medication.

I have next to no libido, very numb to pretty much most things including sexual feelings too/orgasms ect. We’ve tried adjusting the dose and it was mentioned about potentially adding Wellbutrin (buproprion) however psychiatry advised against this and have now suggested I tried wean down to 100mg sertraline and then add 15mg Mirtazapine.

I’m just wondering if anyone has done this and what your experiences have been? I’m worried about serotonin syndrome increased risk, but I’m also curious as to whether this reduced anyone’s negative side effects relating to numbness or lack of libido/emotional numbness.

Thanks for taking the time to read this.

I've been struggling with insomnia that seems strongly connected to hyperarousal. My sleep problems tend to become much worse when I'm emotionally stimulated – and not necessarily because of negative stress or anxiety. Positive excitement, anticipation, changes in routine, important events, and especially romantic feelings can put my nervous system into an extremely alert state.

When that happens, I can feel physically tired and desperately want to sleep, but my brain/body just doesn't seem to switch into sleep mode. I may fall asleep very late and wake up relatively early, often getting around 5 hours of sleep or less. The next day I feel exhausted and unrefreshed.

My psychiatrist prescribed mirtazapine mainly to help with this combination of hyperarousal and insomnia.

I started mirtazapine on July 29.

Initially I took ¼ of a 30 mg tablet (7.5 mg). It definitely had an effect on me: I felt calmer and more relaxed, and it reduced that feeling of being "wired." It also increased my appetite.

However, the actual improvement in sleep has been disappointing. Since starting on July 29, I can probably count only about two nights when I felt I slept really well. Most nights I still fall asleep very late and sleep around 5 hours, sometimes less.

I also experienced dizziness/heaviness during the day.

On August 16 I increased the dose to 15 mg (½ tablet) according to my psychiatrist's instructions.

The 15 mg dose definitely relaxes me. I can actually feel the calming effect. But so far, it still doesn't make me fall asleep easily. I can lie there for hours despite feeling physically relaxed. For example, one night I didn't fall asleep until around 2:30 a.m. and woke up at 7:30 a.m.

What concerns me most now is the daytime heaviness and cognitive fog. Before mirtazapine, poor sleep already made me tired during the day. Now it sometimes feels like I have both the exhaustion from insufficient sleep and the sedation/heaviness from the medication.

I'm noticing reduced concentration and mental sharpness, and I feel like my life is somewhat "on hold" because there are so many things I want and need to do, but I'm too tired and unfocused to do them properly.

My psychiatrist wants me to stay on 15 mg for three weeks before reporting back. I've only recently increased to 15 mg, so I know it's early. I'm planning to give this dose a few more nights and see whether anything starts changing.

I'm curious about other people's experiences, especially those who took mirtazapine primarily for insomnia/hyperarousal rather than depression:

• Did the sleep benefit improve after being on 15 mg for a while?
• Did the daytime heaviness/brain fog eventually disappear?
• Did it calm you without actually helping you fall asleep at first?
• If mirtazapine relaxed you but didn't improve your sleep enough, what did your doctor eventually do – change the dose, switch medications, or add something else?

I'd especially love to hear from people whose insomnia is triggered by emotional arousal, anticipation or excitement, rather than only negative anxiety.

I’ve reduced to 7.5 for a month from 15mg. I’ve now been at 3.75 for a week. Can I just stop or must I half that again?

how long does the withdrawals last?

Hey people, I'm on day 8 of taking Mirtazapine. Doc prescribed 15mg for stomach problems and it works great for that. Anxiety and depression are pretty much the same, but I guess it'll take a bit more time to get that fixed.

Anyways, my head feels numb. I can fully understand that Mirtazapine blunts emotions a bit, but... I need some motivation and advice, or at least regular info- is it normal? Did anyone feel the same like I do rn?
I'm pretty much unmotivated to do anything and literally dont know what to do with myself so I spend 90% of the day on PC or phone, feels awful.

Thanks.

Hi all. I was on 15 mg mirtazapine for a few months for sleep maintenance insomnia (not depression). I chose it because I had had it for depression before and knew I tolerated it okay. Anyway I didn't like some of the side effects this time and tapered off over a period of about 40 days. I took my last dose which was something like 1-2 mg about five days ago.

Long story short, the past couple of nights I've been waking up at 3 am every morning and it's a coin flip whether I'll get any more sleep after that. I know I've probably just had the final washout and my histamine receptors are still upregulated and that's at least part of what's going on (with the other part being whatever stuff was giving me these early wakes in the first place).

I'm just wondering if anyone has been through a similar situation and can give a rough indication for how long this worse patch might last? And how long until my sleep is reflecting my actual baseline?

Did anyone else have chest tightness/feeling like you can’t breath as a withdrawal symptom?

I’ve been on 100mg sertraline and 15-30mg of mirtazpine for a long time.

It’s a good combo for me it works except in sick of the mirtazapine weight gain

Has anyone successfully swapped out mirtazapine for bupropion?

Thanks for reading I appreciate replies