u/Due_Chapter3027

Hey all. I’ve been on antidepressants since I was 12 and currently on 15mg of Lexapro. Have horrible panic attacks and anxiety recently since my mcas has been rough. I’m not sure if I’m allowed to take thc while on SSRI’s or if I’m likely to react to the gummies? Just wanting to add something more natural to dampen my panic rather than benzos or something. I’m also on 1mg guanfacine and 1 mg Low a dose Naltrexone. Anyone on SSRI’s with mcas and tried this? Big no no? Thanks!

Hey all 2+ years of misery with horrible flu like flares from medications, LDN, mast cell stabilizers, just in general extremely bad. Exercise intolerance, all flared and this mess started 2 years ago when my dog passed away and ebv reactivated while I was living in musty VISIBLY moldy areas… mymycolab came back high for sensitivity to a bunch and have been a complete wreck. Have been out of mold for 4 months and can’t tolerate binders at all. Anyways here are my Cirs labs…

TGF-b1 (tested 3 times) 8,000, 6,000, and now 3,568
MMP-9- 382
MSH- Less than 8 (<8)
VEGF-32
C4A- 1,605

Does this seem like CIRS since I have 11 of 13 symptom clusters, visible mold I lived in, bad MCAS like flares, etc?

Hello guys just wondering how the hell to even help myself here or if I’m just not giving these things a chance. Usually within the first 3-4 days of taking a mast cell stabilizer I quit because the flare is so bad but end up flaring for a week of immune response and flu like symptoms anyway. Have tried ketotifen .25 mg, cromolyn DROPS at a time, LDN, now Mirica (luteolin and P.E.A). I know I’m super sensitive but how do I ever calm my mast cells? Push through? I’m also dealing with CIRS/ Mold illness so my immune system is super dysregulated and my nervous system is in fight or flight and super hypervigilant. I can only tolerate Allegra and hydroxyzine + Pepcid but don’t seem to cut it. Any suggestions welcome thank you.

Hey all have been dealing with 1-2 attacks a month for 2 years now and have an ejection fraction of 80%. When I get the episodes is it typical to have pinching under right rib/diffuse pain to shoulder, extreme nausea, burping, burning stool, waves of dread/panic, bowel cramping, sometimes sweating, coughing randomly, lump in throat? I get so close to throwing up and I get nervous because my lower bowel rumbles and sounds like WW2 when it happens. Is that the bile that quickly was ejected causing cramping and burning stool? I also have bad Silent Reflux but what are you guys with overactive gallbladders experiencing or have?

Hey guys just curious if it’s something that should be done at a certain mileage to prevent oil leaks over time or blow by issues. I know Subaru doesn’t recommend anything but noticed some blow by in my post maf hose which I heard is normal? Is it only something you replace when you have fuel consumption issues etc or do preemptively? Thanks 💪

Was just wondering for men with mast cell issues if it is common for hot flashes to occur or if it’s my CIRS… I also have dysautonomia to a point and maybe it’s that as well. But with my hot flashes I get face flushing and joint pain with muscle twitches during flares so was leaning more histamine/mediators. I get so warm and start to sweat I feel like I’m in menopause or something 😅 I flare pretty frequently whether it’s my mold illness or mcas I’m not ALWAYS sure but this time seems to be mcas from diet. Thank you.

This may be something other than my CIRS like MCAS/histamine/mast cell issues or leaky gut but noticed any time I react to a meal I get body/joint pain WITH random muscles twitching… wonder if that’s the histamine/mediators or more of a “leaky gut” thing. It goes away within an hour or so. But the act of eating sometimes will give me face flushing, bowel rumbling, chest tightness, muscles twitching, headache, then systemic flu like symptoms if I’m already in a moderate flare or already primed to react. Seems like everything is revolved around my gut and other than diet would stuff like zinc carnosine, seeking health histaminX probiotic, glutamine, etc help? Thank you.

This may be something other than my mcas like my CIRS or leaky gut but noticed any time I react to a meal I get body/joint pain WITH random muscles twitching… wonder if that’s the histamine/mediators or more of a “leaky gut” thing. It goes away within an hour or so. But the act of eating sometimes will give me face flushing, bowel rumbling, chest tightness, muscles twitching, headache, then systemic flu like symptoms if I’m already in a moderate flare or already primed to react. Seems like everything is revolved around my gut and other than diet would stuff like zinc carnosine, seeking health histaminX probiotic, glutamine, etc help? Thank you.

Hey all! New to peptides and not sure the best/ most reliable source for KPV capsules would be? Looking for more gentle gut focused rather than subcutaneous injections as I’m pretty sensitive with mast cell issues. Thanks!

Hey guys looking into a peptide or something for my bad gut issues and mast cell problems… heard KPV is great for inflammation and gut permeability issues. My gut is wrecked daily and bowel pain/rumbling gives me flu like symptoms. Whenever my bowel/gut is upset it triggers my whole body flares. Any brand you guys recommend? I’m very sensitive lol.