Clinical Trial Shows Switching to Oral GLP-1 After Injectable Therapy Can Help Maintain Weight Loss | Research | Advances in Diabetes & Endocrinology | NewYork-Presbyterian

Clinical Trial Shows Switching to Oral GLP-1 After Injectable Therapy Can Help Maintain Weight Loss | Research | Advances in Diabetes & Endocrinology | NewYork-Presbyterian

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u/requiredelements — 1 day ago
▲ 4.0k r/PMOSonGLP+2 crossposts

I’ve never been under 200 lbs as an adult. I’m still in disbelief.

Started January 2025 at 325 lbs. Diagnosed with PCOS and pre diabetes. Currently I weigh 177 lb and I am 30 lbs from my goal. It seems surreal. I feel like I have my life back and then some.

u/requiredelements — 9 days ago
🔥 Hot ▲ 9.0k r/PMOSonGLP+3 crossposts

AOC took to social media to reveal that she is currently going through the process of freezing her eggs, pulling back the curtain on the physical and emotional realities of family planning while navigating a high-profile political career.

u/Electronic-Bus-3494 — 11 days ago

Girl or boy? 12 weeks

12 weeks exactly according to LMP but I think I ovulated late in my cycle and baby is measuring a couple days behind.

Take a guess. I can’t even tell which structure is the nub!

u/requiredelements — 13 days ago
▲ 159 r/PMOSonGLP+1 crossposts

Stalled on Zepbound? Eli Lilly to allow more patients to apply for compassionate use of retatrutide

“For a limited number of patients who meet specific medical criteria and cannot enroll in a clinical trial, we believe it is medically appropriate to make authentic retatrutide available before FDA approval, consistent with FDA’s guidance,” a Lilly spokesperson told STAT.

https://www.statnews.com/2026/08/03/eli-lilly-retatrutide-mystery-patient-doctors-seek-same-access-their-patients/

Also somewhat encouraging to read the article and to learn that friend of the sub, Dr. Spencer Nadolsky, was able to have a patient preliminarily qualify.

u/Schwettes — 17 days ago
▲ 92 r/PMOSonGLP+1 crossposts

Mounjaro saved my life

I’ve been on this medication for a couple of weeks. I have nothing to say except my A1C went from 5.7 pretty much pre diabetes down to 5.4 (I’ve been prediabetic priori a few years ago when I was put on metformin), went from 160+ days between periods to 35-40 days, I tested positive for ovulation today, I lost 7 kg in bit over a month (20 more kg to lose), my relationship with food completely changed, and I have a libido again, I used to suffer of dryness and recurring infections, intercourse with painful all the time. My skin went completely clear after a very aggressive acne and a cyst I needed surgery due it getting infected (I spent 2 weeks with an open wound in my face having the infection drained and taking antibiotics). It was near my ear and the infection was spreading towards the ear, so I had an emergency procedure.

I’ve never felt healthier and happier since I got diagnosed at 17, that was 10 years ago.

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u/Legitimate_Boat_1085 — 18 days ago
▲ 213 r/PMOSonGLP+1 crossposts

91kg -> 64kg in 10 months

10 months into my weight loss journey, have not seen a number this low since i was a kid. Mounjaro + metformin with a strict calorie deficit + regular exercise. I genuinely never thought i would see the day where my BMI was within “normal” range.

u/Afraid_Arugula_671 — 19 days ago
▲ 133 r/PMOSonGLP+1 crossposts

Finally my turn. 85kg -> 55kg

Lost this weight naturally a few times as you can see. Couldn't get it to stick until I started GLP1 in September 2024. Paired it with weight lifting and a good diet to preserve muscle. Also finally pre diabetes free !

u/Educational_Fail_408 — 19 days ago
▲ 2.3k r/PMOSonGLP+3 crossposts

-80 pounds on Zepbound

Along with taking Zepbound, I started lifting, doing cardio about four times a week. I ate a high protein, low-carb, low sugar, diet while tracking . This medication has been a game changer for PCOS/PMOS.

u/Adept_End_7852 — 24 days ago
▲ 33 r/PMOSonGLP+1 crossposts

im in SHOCK at how painless this period has been (on tirzepetide)

4 months post surgery, 7 weeks on tirzepatide (2.5mg) i am SHOOK and how painless and easy this menstrual cycle has been. this is crazy because im so used to being completely flat out and in agony every period, unable to move, i am genuinely so surprised but SO HAPPY.

(also, my acne has improved significantly on tirzepatide + from using azealic acid, and i've already gone back to my 'normal' looking self in terms of inflammation etc. its also a lot easier for me to bounce back from flares these days)

i have cramps today on my period but they are SO MINOR i imagine this is what it feels like for someone without endo?!

i just wanted to share the good news because it can be so consuming focusing on the negatives and things you want to improve, but i genuinely cant believe it.

if you've been thinking about GLP1 usage for similar issues, i'd really suggest doing your research and looking into it. i felt the inflammatory benefits instantly (for context i also have an undiagnosed insulin problem / possible PMOS so this affects my overall picture too, but this has worked miracles for me)

big love to everyone x

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u/lilbbtee — 1 month ago

Does anyone manage their PCOS /PMOS primarily via a telehealth service?

Services like Allara, PCOS Sisters.

If so, which are you using? What has been your experience? Are they prescribing your GLP-1? How much do they charge for refill scripts?

reddit.com
u/requiredelements — 2 months ago