ROB 2 tool for SR and MA of RCTs
Hi. I’m doing an SR and MA on the safety and efficacy of a certain group of drugs.
It’s a big study with a lot of outcomes. I wanna use Rob 2 since Rob 1 is outdated but I see many other SR and MAs on PubMed attaching only a single risk of bias figure for all the studies included when I thought each major outcome had to have its own risk of bias figure across each study under Rob 2, which assess each outcome on its own, as opposed to Rob 1 where each domain assesses the study itself, not an outcome of it.
Can anyone explain why or how this is done? Do they just choose one outcome in each study to fill the domains for that whole study or do they only do this when all outcomes under one study have the same domain assessment so that a single figure would represent all the risk of bias assessment of the outcomes in that study? (e.g., hba1c and QoL having a yes in D3).
Please help. Thanks in advance :)