u/ReasonableFig8954

Had MS for 16 years

Been on ocrevus just over a year

The last 6 months I thought I was dealing with anxiety and depression, but iv been in and out of hospital multiple times in last few weeks

3 new lesions

I just feel like death and this has compounded my depression and anxiety massively or was the cause of my depression which no antidepressants are touching

I think im getting another relapse too as my stress is so high.. I have tremors and vibrating in my hand and stomach feel maybe have Parkinson's too as I read the symptoms im only 40 yr old. I have appointment with neurologist tommorow

The fatigue has increased to another level I cant function

Im so low I cant see any hope or a future only thoughts in my head is my life is not livable like im on verge of something bad happening, I know probably anxiety talking

Nothing seems real anymore my cognitive functions are so low

Im in so much pain everyday, mentally, physically and im crushed by fatigue and brain fog. I dont feel in control of my body or mind anymore.

Iv so far not seen any benefits I feel worse and have dpdr from this so bad

Last 3 days im stuck in bed literally zero energy and feels like my brain is full up.. very dark thoughts too

And I havenet just started its been 4 weeks

15mg 10 days

10mg one week

The other lower doses

I take it this is not going to work for me as I feel awful? Really dark hole

Its been 6 months and im at rock bottom

Its been daily depression and anxiety eating me alive.. iv tried so many antidepressants

Now trintellix 4 weeks and im just getting worse and worse.. no positive signs at all.. have crazy dpdr aswell and zero energy

I really think i just need to stop them all and see where I am at it surely cant be worse then this

Have been on 15mg for 10 days now

10mg for a week

5mg for the rest

This depression has hit me harder than ever. I can barely move out my bed I have no energy at all its like all my dopamine has tanked massively

I got given lamotrigine last week took 4 doses and stopped as felt totally out of it.. maybe its also that?

I feel like vortioexitine should be doing something positive by now. Im completely low

Like literally feels like hell

Nothing seems real yet still get crazy anxiety

Then feel totally depressed like nothing is real whats the point

Antidepressants not helping

What else to get out this hell

So I have been having really bad anxiety for months which caused severe depression crying all the time, hopeless, extreme agitation etc

I started trintellix after other meds havent done much

But I feel like depression is changing form

Now

- Absolutely zero energy like my brain and talking is such an effort and slowed.

- Not crying but, not anything much. Have no energy at all

- Feels like I cant even think to ruminate to tap into anxious thoughts etc

- Head full of pressure where before it felt empty

Does this mean getting worse, improving or nothing?

So I have been having really bad anxiety for months which caused severe depression crying all the time, hopeless, extreme agitation etc

I started trintellix after other meds havent done much

But I feel like depression is changing form

Now

- Absolutely zero energy like my brain and talking is such an effort and slowed.

- Not crying but, not anything much. Have no energy at all

- Feels like I cant even think to ruminate to tap into anxious thoughts etc

- Head full of pressure where before it felt empty

Does this mean getting worse, improving or nothing?

So I have been having really bad anxiety for months which caused severe depression crying all the time, hopeless, extreme agitation etc

I started trintellix after other meds havent done much

But I feel like depression is changing form

Now

- Absolutely zero energy like my brain and talking is such an effort and slowed.

- Not crying but, not anything much. Have no energy at all

- Feels like I cant even think to ruminate to tap into anxious thoughts etc

- Head full of pressure where before it felt empty

Does this mean getting worse, improving or nothing?

My MS has floored me

My anxiety and depression at all time highs I cant relax all day

My fatigue and brain fog is debilitating causing dpdr

Iv been dealing with this months now tried multiple meds

I cant stop feeling whats point of all this, whats point in struggling daily feeling rubbish and not achieving anything

Im letting my partner down, my family even my pets as im too exhausted or anxious to do anything

How did you push through this?

Started ocrevus last march, was pretty stable on copaxone for several years.

This last 6 months has been the worst in my life being diagnosed with extreme anxiety and depression

But its more then that, had MRI few weeks ago and they said there is a couple new lesions in left part of brain but not active.

So probably ties in with when I started feeling bad

Thought ocrevus stops lesions?

Does left part of brain affect my speech, thoughts anxiety etc as this has all gone downhill

I have fatigue like nothing iv ever experienced like im about to pass out.

I have Debilitating anxiety which has caused severe depression

So on 25mg at night for 3 days and I woke up with no physical anxiety coursing through body

Is this normal?

On a bad note I have extreme fatigue and brain fog from it. When will it pass

Iv been getting worse and worse my fatigue and brain fog is unbearable I can barely do anything..

Even if i do im just surrounded by the fog in unreality like nothing is real

The fatigue hits so hard sometimes that I feel like I am about to go unconscious or something

This then makes me panic with zero energy

Iv tried so many antidepressants but the problem is the fatigue is doing it

Im experiencing all of the above, fatigue and brain fog was always my worst symptom of MS

Now its like 100x from the meds side effects, I recently started trintellix + lamotrigine.. to the exhaustion from depression and anxiety I feel like im in another world im so tired

Literally I pushed myself to try put some furniture together today and couldnt even get half way through I felt like collapsing from exhaustion

Anyone else had all these combined? How did you fet through it.. its been months living in this hell on earth

I already have extremely bad fatigue and brain fog and lots of depression and anxiety

I started 25mg 3 days ago and the fatigue is crazy

Does it get better?

I felt small difference in physical anxiety already so really want to stick to this but I have MS too so am very sensitive to anything sedating

I have so many thoughts popup

E.g replay the worst panic attack how you felt

How is derealization are things real etc

I tend to get pulled in and engage

Does anyone do eye movements when thoughts come instead of engaging with the thoughts.. does it help

I guess il be doing it every 10 minutes lool

Its like my brain is running at 100mph im getting zero peace and all day overwhelmed with anxiety and depression and thoughts

I’m struggling badly with anxiety, depression, derealization and constant looping thoughts. My brain keeps replaying panic episodes, hospital memories, and fears that I’m losing my mind.

I’m currently on 15mg vortioxetine (worked up from 5mg/10mg over about 4 weeks, with only about a week on the higher doses). Since increasing, I’ve had intense anxiety, overstimulation, racing thoughts, derealization and panic feelings, but also occasional moments where my brain feels slightly less “offline.”

Trying to work out whether this sounds like activation/startup effects, severe anxiety/depression, or whether the medication may not be right for me. Has anyone experienced similar and improved?

My DPDR is so bad at the moment

I am suffering extreme anxiety and depression for months

But the depersonalisation is especially relentless and getting stronger

Its like I look at my family and barely recognise them, I dont even think I am real

Struggling everyday with it plus the brain fog and depression ontop is kicking my ass

No meds have worked yet. Any help?

I went to neurologist moaning about extreme Debilitating fatigue and brain fog.

He done the usual checks and said youve had MS for 15 years and are doing well you wont be disabled

Im like I come here for cognitive issues not physical my MS has always smashed me cognitively and they dont take any notice

So iv been going through a tough time recently with really high anxiety and brain fog

Every med thats meant to work or can work just incapacitates me

Literally things like propanolol or beta blockers, some meds like mirtazipine or abilify. Put my fatigue and brain fog into another dimension like im not even here.

Why am I so sensitive to meds that trigger cognitive issues.. anyone else?

Just want to get a feel if this actually works for anxiety

How extreme was you with 10 being the highest e.g constant physical anxiety, couldnt go anywhere etc

What mg helped or did not help and how long.. did it get worse before better