EBRT 4 years ago: Why would my PSA jump from .7 to 3.52? Thoughts?
First off, yes I have a follow up appointment and will be discussing with my urologist.
64YO, diagnosed in 2021 with PSA of 6.5 and Gleason 3+4. Went through EBRT in 2022, no hormones or any other treatment. Just had my first PSA in over a year. Back in 2024 my PSA was below one, I think it was .7. At that point my urologist told me I didn't have to get another check for a year.
Missed my 2025 appointment due to scheduling but finally got around to getting a new doctor (previous one is no longer with the practice, which also took some time since we live in a small city that doesn't have a lot of providers.)
Just got the results in and it says PSA of 3.52.
That seems like a crazy high jump for an 18 month period, especially after EBRT.
My first thought is that the test isn't good and I did something to artificially inflate it. I had just undergone a surgical procedure to my nose (septoplasty) and was in a lot of pain. I noticed on my CBC that my white cell count was really high and I figured that might be a reaction to the surgery.
(Side note: Nasal surgery sucks. You have no idea how many nerve endings you have in your nose until you get cut on there.)
Anyway, as I said above I do have a follow up consult with the urologist and I'm hoping he says he doesn't believe the results and schedules another PSA test.
But since I'm a worrier and I have time, I thought I'd throw this out to the group: How can PSA jump that quickly in 18 months for someone who has (presumably) a dead prostate from radiation?