Those of you on Seroquel monotherapy - what dose are you on?

I've recently started Seroquel monotherapy and am curious as to the dose most people are on. I'm still working out where I'll sit at, but at this stage it looks like somewhere between 150-300mg. 300mg has me very calm, but is where some sides are starting to show, so trialing slightly lower doses.

I know everyone is different, but just curious as to what the ranges are.

My doc said the standard dose is 300-600mg, but it varies quite a bit.

I am taking the IR dose.

I had drug induced hypomania and no psychosis hence my dosage may be a little lower. (Was on Lexapro, Wellbutrin and Vyvanse, now only taking Vyvanse 2-3 days a week and no Lexapro or Wellbutrin)

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u/InsideMuch4907 — 1 day ago

When does the appetite rebound go away and I stop eating like a starved animal?

So I stopped my stimulants around a week ago, feeling so much better mentally. Decided to take them 2 times a week for now.

The problem I have is, I am eating like a starved animal. I didn't realise how much stims were reducing my appetite. Now I am having an insatiable hunger, also drinking coca-cola, and I've never even been a fan of soft drink!

Is this just what my new baseline is like or does it normalise after time?

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u/InsideMuch4907 — 2 days ago

Please tell me that Seroquel will keep working like this?

I had a prolonged hypomanic episode triggered by starting three medications:

- Wellbutrin

- Vyvanse

- Lexapro

I slowly came off everything about 6 months ago, finally coming off the Vyvanse around 1 week ago. I've also started Seroquel 150mg at night.

I feel a sense of calm I haven't had, ever. My mood is also good, but not hyper like it was before. The first days of the Seroquel I did nothing but sleep, but not that I'm used to it I'm looking forward to this medication.

Please tell me others have had a positive long term experience.

I take Tirzepatide so I am hoping my weight stays stable.

Those of you on Seroquel monotherapy, what dosage are you on?

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u/InsideMuch4907 — 4 days ago

Has anyone noticed any side effects relating to their sexual function?

I started Seroquel recently and am on 150mg which has helped with my sleep and mood, however I've noticed my libido is lower. I am not sure if it's the medication as my libido flucuates a bit.

I wanted to find out if it was normal for most people to have some libido side effects.

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u/InsideMuch4907 — 4 days ago

How long for Mirtazapine fatigue/sedation to go away?

Hi all, I am considering trialing Mirtazapine, but curious as to how long it took you all to get over the sedation in the morning?

I have tried Quetiapine which is 150mg and found once the sedation goes away works very well as an antidepressant, the receptor profile is quite similar to Mirtazapine so wanting to try that as a safer long term option.

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u/InsideMuch4907 — 5 days ago

Bachelors Degree for study of ancient history/ancient civilisations + religion?

Hi all,

I'm already employed and hold a bachelor's in a STEM field, but I'm keen to go back to university to study something purely for interest's sake. I'm specifically drawn to:

- Ancient history

- Ancient civilisations

- Archaeology

- Religion and theology

Ideally I'd like a degree that marries these together rather than treating them as separate silos. I'm especially interested in "pre-flood" civilisations and in how religion and mythology shape the way we interpret the past.

At the moment I'm reading a lot about a pattern I find fascinating: how many unconnected civilisations share the idea of "giants" who once roamed the earth, often described as the offspring of gods and humans. You see versions of it in the Hebrew Bible (the Nephilim), in Greek mythology, and in other ancient traditions. Whether that reflects cultural diffusion, shared human imagination, or later borrowing is exactly the kind of question I'd love to study properly.

Since I already have a degree and would be doing this part-time around work, I'm open to postgraduate options (a grad cert or master's) as well as undergrad.

If anyone can point me in the right direction: programs, departments, or even good entry-level reading, I'd really appreciate it. Thanks!

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u/InsideMuch4907 — 6 days ago
▲ 55 r/ausadhd

Update - 4 days no ADHD meds

I made a post 4 days ago about taking a break from/stopping my stimulant medication. I pretty much slept 14-16 hours a day everyday, but, today I was just watching youtube videos and I started laughing.

I realised, during the period I used stimulants (Vyvanse or Dexamphetamine) I lost all my sense of humour. I've been laughing, chilling and just generally feeling so much better.

I am demotivated as fuck to do any work, but I feel alive.

Only sharing this incase anyone else felt the same way I did before.

I think after taking a month off I'll go back to only using Vyvanse/Dex 1-2 days a week maximum.

Happy Tuesday!!

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u/InsideMuch4907 — 6 days ago

Just took 300mg Seroquel for the first time, what should I expect?

I am newly possibly diagnosed, trialling Seroquel 300mg. What should I expect tonight, over the next days and weeks?

I need to get these hypomanic and depressive episodes under control or I am afraid of what will happen/become of me.

Any anecdotes and experiences are appreciated.

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u/InsideMuch4907 — 8 days ago

30's | Self Employed | 6 years in business

YTD earnings, bonus is director fee. Normally retained as company profit, however need cash to fund personal investments.

u/InsideMuch4907 — 8 days ago
▲ 69 r/ausadhd

Life after ADHD meds

To those of you who were on meds but decided to stop, what's life like now?

I've made the decision to stop my ADHD meds, because upon reflection, though I am more productive and able to work more I feel like every other aspect my life is materially worse. My chaotic and funny personality is gone. I am no longer spontaneous and impulsive, rather preferring to be productive. I feel like I don't socialise as much. I don't go to the gym as much as I used to, because my brain is sufficiently dopaminified.

I realised that the coping mechanisms I developed over the years such as gym, movies, gaming were also a part of my personality which the stimulants have removed the need for. I got such a huge dopamine rush lifting heavy things and going on the treadmill after, 5-6 days a week. Now I just go 1-2 times.

I don't feel as creative as I used to either, it's just a weird sensation. I miss the chaos in my head, life just feels so dull and boring now. The only thing I am very glad for is that I stopped drinking alcohol (will be a year in 20 days), thanks to stimulants, I worry that may return.

Anyone else had similar feelings?

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u/InsideMuch4907 — 10 days ago

Can Intuniv make you depressed and demotivated?

I'm on Intuniv which at first I loved, but I've noticed I'm getting really depressed, like more depressed than I have ever been in my life. I also am lacking any motivation.

I started Intuniv like 6 weeks ago when things started to go downhill but wondering if it's just a coincidence?

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u/InsideMuch4907 — 11 days ago

How do I come off this shit? I can't get dialed in.

I'm 6 months in and no closer to being "dialled in". I've spent the last 2 days just crying thinking about all my failings in life. I'm feeling to melancholic and emotional.

TRT is just too hard.

I've pinned every day, taken IM and subcut, taken AI's, shaved my balls, you name it and I've done it.

The problem is, I feel like I can't enjoy sex unless I take HCG, but I take HCG and I become an emotional wreck. Damned if I do, damned if I don't.

Anyone have any unorthodox advice before I just quit this and what is the best way for PCT to come off the TRT? Just stop cold turkey or stop and use a bit of HCG to keep the balls ticking along?

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u/InsideMuch4907 — 12 days ago

Just needing support and encouragement as I try to come out of a hypomanic state

I am not asking for medical advice so please don't delete this thread.

I just want human to human interaction, support and stories from others experiences.

I am certain I am in a hypomanic state. I won't get in to specifics, but I've done some risky things over the last few months and am on the verge of fracturing some of my interpersonal relationships.

It all started last year when I was put on Lexapro, Wellbutrin and Vyvanse at the same time. I felt amazing. I was so productive, didn't need sleep and felt ontop of the world. The irritability started to creep in and earlier this year I weaned myself off the Lexapro and Wellbutrin. Things started to improve, I reduced my Vyvanse dose and I was on the come down.

I engaged a Psychiatrist and he's still not 100% certain, but thinks if I ever need an antidepressant I should be on high dose Seroquel, for now he tells me to take 50mg to just sleep. I had already self weaned myself off the Lexapro and Wellbutrin before I saw him.

My Psychiatrist also wants me to stop the Vyvanse, which I a have decided I will do and not take another pill.

I spent this evening writing a letter to end a 10+ year relationship so that I could go live in a fancy apartment alone. I just don't feel right. It's like something is wrong but I can't quite put my finger on it.

Anyways, I am going to take 100mg of Seroquel, try sleep it out the next few days and see how I go.

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u/InsideMuch4907 — 13 days ago

What to expect with Vyvanse withdrawal/timeline?

I have decided to stop Vyvanse temporarily, for at least 1 month. There have been some issues with my relationships which I attribute to Vyvanse. I am far less social and instead want to be focused, productive and working. I spend less time speaking to family and friends.

I currently take 60mg vyvanse once a day, I am also prescribed Dex Boosters 5mg each, two a day, but I rarely if ever take them.

I am considering two options:

  1. Just go cold Turkey and take a few days of sick leave, try get some exercise in and see how I go.

  2. Reduce to say 30mg for a week, then 15mg then stopping.

I am at a point where I am literally drafting a letter to my spouse of 10+ years for a seperation, and it's not quite clear if it's actually me or the medication.

Anyone want to share theiir experiences?

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u/InsideMuch4907 — 13 days ago

M/30/6'1" [131kg > 100kg = 31kg] 14 months or so, more pics in comments.

Aiming to lose another 5-10kg we'll see how I go.

200g protein a day, 4 days lifting (Upper, Lower, Upper, Full)

u/InsideMuch4907 — 14 days ago

Thought this sub needed some melanated progress pics 30kg+ down

Don't get me wrong, I appreciate all the delegates from the creamy community, but to my melanated friends out there we need to start posting more!

14 month progress.

6ft1"

131kg to 100kg

Stopped drinking alcohol July 27th 2025.

Goal weight, unclear, I think I will be happy with another 5-10kg.

u/InsideMuch4907 — 14 days ago

Where to from here and advice on SMSF?

Situation:

Early 30's, SO and I have a combined SMSF as of earlier this year. The contents of the SMSF are:

SMSF Position

1. Investment Property (Call it IP5)

- 1.3M value
- 900k debt
- Renting $1,100 per week

2. Cash

- $50,000

3. Income from concessional contributions

- Approx $65,000 pa.

SMSF Net position:

$450,000 nw

Cashflow:

$115,000 p.a inflow

$75,000 p.a outflow (mortgage + expenses of SMSF/accountant)

Net cashflow of $40,000 pa.

We are in two minds on how to proceed. We were considering linking our CMA account with a brokerage and just buying 40k parcels of shares on an annual basis set automatically for a 25/75 split of VAS/VGS.

The other option was to pump the 40k cash in to the mortgage and, make some non concessional contributions. We have a reasonable out of super cashflow with around $30,000 per month excess cash after our living expenses and tax.

We were considering doing maybe $15,000 per month as a non concessional contribution to super and save $15,000 per month as cash. We have an offset for our other IP's but given it's all tax deductible not the biggest concern for us.

If we do the $15,000 non concessional contributions we estimate that the SMSF would be paid off in around 4 years and be producing ongoing cash with minimal expenses which is very tempting. But then again the idea of the debt being eroded away by inflation is equally appealing. I think financially paying it off slowly makes more sense but there's a mental satisfaction of paying it off....

Outside of super investments:

IP1 (Principle and Interest - as our old PPOR, before moving out)
- 2.25m value
- 1.8M debt
- 1.6k per week rent

IP2 (Interest only)
- 1.3M value
- 1.18M debt
- 1.3k per week rent

IP3 (Interest only)
- 900k value
- 700k debt
- 725 per week rent

IP4 (Interest only)
- 850k value
- 700k debt
- 650 per week rent

Cash
- 150k

We had ETF's and BTC previously but sold out of all of them to fund our property purchases.

After all expenses we have leftover approx 30k per month to save/invest. Self employed under pty ltd nil PSI (private ruling) so flexibility in how we pay ourselves.

Goals:

- We would like to purchase a house which will be PPOR in 3 years time, so want to save enough cash for that.

- Would like to acquire 1 more IP which would be more of a holiday home, but this is distant goal in 5-10 years.

- At some stage would like to slow down hours maybe in 5-6 years.

- Possibly considering given all IP's are grandfathered for NG, refinancing in 5-6 years, taking all the equity out and purchasing shares.

So, with the main focus on the SMSF, what would you do in that situation? Also what would you do generally with regards to investments outside of super? Any interesting thoughts and ideas would be appreciated.

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u/InsideMuch4907 — 14 days ago

Stimulants changing personality and how to come off them?

Hey all,

I've been on Vyvanse for around 12 months now. My anxiety is a lot lower, my focus is good and I'm more productive but I feel that they've significantly changed my personality.

A lot of my quirks and traits have gone and I feel like I'm quite emotionally numb or blunted. I'm not as affectionate and am very much wanting to just "be productive".

It's causing issues and I am wanting to come off so some advice about stopping stimulants to those that have.

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u/InsideMuch4907 — 16 days ago